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In response to COVID-19, some breast cancer trials have temporarily stopped enrolling new patients. Use the contact information in our trial listings to call or email the research site for information about a trial's status.
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Currently viewing trials
(Last updated: July 24, 2021)
BRCA1/2 (inherited)
Chemotherapy
Hormone Therapy
Radiation Oncology
Surgery
Surgery: Reconstruction
Targeted Therapy: All
Targeted Therapy: Anti-HER2 Therapy
Targeted Therapy: CDK Inhibitors
Targeted Therapy: PARP Inhibitors
Targeted Therapy: Tumor Mutations
Targeted Therapy: Other Targeted Therapy
Vaccines and Immunotherapy
Other Treatment
Activities
Complementary and Alternative Medicine
Decision Support
Diagnosing Breast Cancer
Genetics/Family History
Having Children
Lymphedema
Managing Side Effects
No Travel Required
Predicting Response to Treatment
Preventing Breast Cancer
Preventing Recurrence
Screening
Support/Education
Surveys/Interviews/Registries
AKT
ALK
AR
BARD1
BRCA1/2 (tumor)
BRIP1
CD205
CD70
CHEK2 or CHEK1
ESR1
FGFR
HER2/ERBB2
HLA
MET or C-Met
NTRK
PALB2
PIK3CA or PI3K
PTEN
RAD51
RAF (including BRAF)
RAS (KRAS or NRAS)
RB
ROS1
TP53
NEAREST SITE: 2108 miles
Ohio State University Comprehensive Cancer Center
Columbus,OH
VISITS: 1 visit that coincides with surgery
PHASE: NA
NCT ID: NCT04537312
Using A Robot to Help with Nipple Sparing Mastectomy for Stage I-II Breast Cancer & DCIS
Prospective Pilot Study of Robot-Assisted Nipple Sparing Mastectomy (RNSM) Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will recieve the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Robot-assisted Nipple Sparing Mastectomy</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A nipple-sparing mastectomy leaves your nipple, areola and the surrounding skin--but removes the breast tissue underneath. </li> <li class="seamTextUnorderedListItem">Nipple-sparing mastectomies can be difficult to perform because they use small incisions (openings). </li> <li class="seamTextUnorderedListItem">Researchers believe that using a robot will make it easier to use small incisions during surgery. </li> <li class="seamTextUnorderedListItem">The robot used in this trial is called the da Vinci surgical system. It is approved for use in other surgeries, but its use in this study is considered experimental.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04537312' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/research-news/consider-cx-characteristics-for-nipple-sparing-mx' target='_blank'>Breastcancer.org: In Appropriate Women, Nipple-Sparing Mastectomy Doesn’t Lead to Higher Breast Cancer Recurrence Rates</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.davincisurgery.com/procedures/general-surgery##' target='_blank'>Intuitive Surgical Device Information Page: Da Vinci Surgical System</a> </li><li class='seamTextUnorderedListItem'><a href='https://wjso.biomedcentral.com/articles/10.1186/s12957-019-1567-y' target='_blank'>Journal Article: Breast Cancer Robotic Nipple Sparing Mastectomy: Evaluation of Several Surgical Procedures and Learning Curve</a> </li></ul>
NEAREST SITE: 2549 miles
Rutgers Cancer Institute of New Jersey
New Brunswick,NJ
VISITS: 4 visits before surgery; 5 visits per week, for 6 weeks after surgery, over 4 months
PHASE: NA
NCT ID: NCT04871516
Radiation Therapy Before and After Surgery for Stage I-III, Node-Negative Breast Cancer
A Single Center Phase II Prospective Clinical Trial to Assess the Feasibility of Preoperative Radiation Boost in Breast Cancer Patients Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Radiation therapy, 4 times before surgery</li> <li class="seamTextUnorderedListItem">followed by breast surgery</li> <li class="seamTextUnorderedListItem">followed by whole breast radiation therapy, 5 days a week, for 4 to 6 weeks</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Radiation therapy uses high-energy x-rays to kill tumor cells.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04871516' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/treatment/type/radiation-therapy/' target='_blank'>Susan G. Komen: Radiation Therapy</a> </li><li class='seamTextUnorderedListItem'><a href='https://moffitt.org/newsroom/press-release-archive/radiation-therapy-prior-to-surgery-reduces-the-risk-of-secondary-tumors-in-early-stage-breast-cancer-patients/' target='_blank'>Moffit Cancer Center: Radiation Therapy Prior to Surgery</a> </li></ul>
NEAREST SITE: 2695 miles
Tufts Medical Center
Boston,MA
VISITS: Coincides with surgery
PHASE: II
NCT ID: NCT04603911
Comparing Two Different Pain Therapies for Use With a Nerve Block During Mastectomy with Immediate Reconstruction
An Investigator-Initiated, Double-Blind, Patient-Controlled, Randomized Control Trial Comparing the Effectiveness of Liposomal Bupivacaine to a Solution of Bupivacaine, Epinephrine Clonidine and Dexamethasone in Bilateral, Single Shot, Erector Spinae Plane Blocks During Oncoplastic Breast Surgery Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups and receive the following during surgery: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Standard of care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Nerve block (ESPB Block), using bupivacaine, epinephrine, dexamethasone and clonidine</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Nerve block (ESPB Block), using liposomal bupivacaine</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A nerve block is a procedure used during surgery. For this trial, the type of nerve block used is the ESPB Block. </li> <li class="seamTextUnorderedListItem">During your surgery, a local anesthesia will be injected into the muscles of your chest and arm pit. This injection will numb the nerves in the area where the surgery will be performed, and this may decrease the pain you feel after your surgery is over.</li> <li class="seamTextUnorderedListItem">Bupivacaine hydrochloride (Marcaine) is the standard of care pain therapy for this procedure.</li> <li class="seamTextUnorderedListItem">Liposomal bupivacaine is a form of Bupivacaine that may provide longer or better pain relief.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04603911' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.clinicaloncology.com/Breast-Cancer/Article/12-19/Benefits-Seen-With-Use-of-Regional-Blocks-For-Bilateral-Mastectomy-With-Reconstruction/56690' target='_blank'>Clinical Oncology News: Benefits Seen With Use of Regional Blocks For Bilateral Mastectomy With Reconstruction</a> </li><li class='seamTextUnorderedListItem'><a href='https://en.wikipedia.org/wiki/Bupivacaine' target='_blank'>Wikipedia: Bupivacaine</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.asra.com/asra-news/article/182/con-liposomal-bupivacaine-a-mission-inco' target='_blank'>American Society of Regional Anesthesia and Pain Medicine: Liposomal Bupivacaine, A Mission Incomplete</a> </li></ul>
