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Find Breast Cancer Clinical Trials That Are Right For You

The clinical trials listed below are open in the U.S. for people with DCIS (stage 0), stage 1, stage 2, stage 3, or stage 4 (metastatic)
breast cancer. Clinical trials are available for people who are newly diagnosed with breast cancer, currently in treatment, experiencing
breast cancer recurrence, living with metastatic disease, as well as breast cancer survivors who have completed treatment.

Use the search box and filters to find a trial that’s right for you.


Currently viewing trials
(Last updated: December 03, 2024)

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Radius (miles): All U.S.

20 All U.S.
Early stage    Advanced 
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Phase    I     II     III 
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Treatment

Brain Mets

BRCA1/2 (inherited)

Chemotherapy

Hormone Therapy

Leptomeningeal Disease

Radiation Oncology

Surgery

Surgery: Reconstruction

Targeted Therapy: All

Targeted Therapy: ADC

Targeted Therapy: Anti-HER2 Therapy

Targeted Therapy: CDK Inhibitors

Targeted Therapy: PARP Inhibitors

Targeted Therapy: Tumor Mutations

Targeted Therapy: Other Targeted Therapy

Vaccines and Immunotherapy

Other Treatment

Non-Treatment

Activities

Complementary and Integrative Medicine

Decision Support

Diagnosing Breast Cancer

Genetics/Family History

Having Children

Healthy/High Risk

Imaging

Lymphedema

Managing Side Effects

No Travel Required

Predicting Response to Treatment

Preventing Breast Cancer

Preventing Recurrence

Support/Education

Surveys/Interviews/Registries

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AKT

ALK

AR

BARD1

BRCA1/2 (tumor)

BRIP1

CD205

CD70

CHEK2 or CHEK1

dMMR/MSI-H

ESR1

FGFR

HER2/ERBB2

HLA

MET or C-Met

NTRK

PALB2

PIK3CA or PI3K

PTEN

RAD51

RAF (including BRAF)

RAS (KRAS or NRAS)

RB

ROS1

TP53

Click here to view online studies and trials that do not require site visits

1

NEAREST SITE: 660 miles
Mayo Clinic in Arizona
Scottsdale,AZ

VISITS: 1 visit

PHASE: NA

NCT ID: NCT06036875

Survey to Understand How Black and Hispanic Women Perceive Their Risk for Breast Cancer

CARE: Cancer Risk Perception and Women of Color Scientific Title

Purpose
To study how Black and Hispanic women understand their current and lifetime risk for breast cancer.
Who is this for?
Women, age 25-50 years, who are Black and/or Hispanic and who live in Arizona or Florida with no history of breast cancer.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Survey, 1 time</li> <li class="seamTextUnorderedListItem">Interview (optional)</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is examining the relationship between risk factors for breast cancer and a person's perceptions of those risk factors and if these relationships are different according to race and ethnicity.</li> <li class="seamTextUnorderedListItem">This study is also exploring how people reduce their risk for breast cancer.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06036875' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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2

NEAREST SITE: 2693 miles
Dana Farber Cancer Institute
Boston,MA

VISITS: At least 2 visits within 4 months

PHASE: NA

NCT ID: NCT06322888

Exercise to Reduce the Risk of Breast Cancer for Women With Dense Breasts

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D) Scientific Title

Purpose
To study how exercise might lower the risk of developing breast cancer by studying changes that occur in breast tissue and blood.
Who is this for?
Women 18-59 years old with dense breasts on a mammogram within the past year and exercise less than 1 hour every week. You must not have a history of breast cancer, be pregnant or breastfeeding, or be receiving hormonal birth control or hormone replacement therapy.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, in person or virtual, 3 times every week for 3 months</li> <li class="seamTextUnorderedListItem">Exercise journal</li> <li class="seamTextUnorderedListItem">Fitbit</li> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2 : Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> followed 3 months later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, 3 months (optional)</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Greater physical activity is associated with a lower risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Exercise may change markers in blood and breast tissue that play a role in breast cancer development.</li> <li class="seamTextUnorderedListItem">If you are in group 1, the exercise program includes aerobic and resistance training exercise with a certified exercise trainer.</li> <li class="seamTextUnorderedListItem">If you are in group 1, a FitBit activity tracker, resistance bands, hand weights, and stationary bike will be provided to you. Hand weights will be returned at end of study.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06322888' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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3

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT04496739

Tools to Help Women Make Decisions About Medication to Prevent Breast Cancer

Cluster Randomized Controlled Trial of Patient and Provider Decision Support to Increase Chemoprevention Informed Choice Among Women With Atypical Hyperplasia or Lobular Carcinoma In Situ - Making Informed Choices on Incorporating Chemoprevention Into Care (MiChoice) Scientific Title

Purpose
To compare the ability of a web-based decision support tool and standard educational materials to help women make decisions about medication to prevent breast cancer.
Who is this for?
Women 35-74 years old with atypical hyperplasia (AH) or lobular carcinoma in situ (LCIS) who do not have a history of breast cancer and have not taken medication to prevent breast cancer.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Educational materials about breast cancer risk and prevention, virtual</li> <li class="seamTextUnorderedListItem">Decision support tool with action plan and breast cancer risk navigation, virtual</li> <li class="seamTextUnorderedListItem">Interview, virtual, 1 time (optional)</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Educational materials about breast cancer risk and prevention, virtual</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Treatment called chemoprevention can reduce the risk of developing breast cancer in people with high-risk breast conditions such as atypical hyperplasia (AH) or lobular carcinoma in situ (LCIS).</li> <li class="seamTextUnorderedListItem">Selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs) are hormone therapy drugs that can be used for chemoprevention. However, these treatments can have side effects.</li> <li class="seamTextUnorderedListItem">Decision support tools are designed to improve informed choice about breast cancer chemoprevention.</li> <li class="seamTextUnorderedListItem">If you are in group 2, the action plan will summarize your breast cancer risk profile, risks and benefits of SERMs and AIs, and personal preferences for chemoprevention.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04496739' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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4

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT05810025

RealRisks Online Program for Breast Cancer Risk Assessment

Integrating EHR and Patient-generated Health Data for Breast Cancer Risk Assessment and Decision Support in a Diverse Multiethnic Population Scientific Title

Purpose
To study how the RealRisks program promotes understanding of breast cancer risk and prevention and perceptions by users of their risk for breast cancer.
Who is this for?
Women, age 35-74 years old, at high risk for breast cancer but who have not been diagnosed with breast cancer.    Full eligibility criteria
Contact research site
Close

Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Use of the RealRisks program, online</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">RealRisks is a web-based patient-centered program designed to improve: 1) accurate understanding of breast cancer risk; 2) knowledge about drugs that could prevent breast cancer, and 3) making choices based on information. RealRisks includes audio and modules about breast cancer risk (including interactive games on risk communication) and drugs that could prevent breast cancer. </li> <li class="seamTextUnorderedListItem">Through RealRisks, study investigators will collect information on breast cancer risk factors to calculate a person's breast cancer risk score and also factors that influence decision-making about prevention. </li> <li class="seamTextUnorderedListItem">RealRisks generates an action plan for patients summarizing their personalized breast cancer risk and preference for prevention.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05810025' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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