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Find Breast Cancer Clinical Trials That Are Right For You

The clinical trials listed below are open in the U.S. for people with DCIS (stage 0), stage 1, stage 2, stage 3, or stage 4 (metastatic)
breast cancer. Clinical trials are available for people who are newly diagnosed with breast cancer, currently in treatment, experiencing
breast cancer recurrence, living with metastatic disease, as well as breast cancer survivors who have completed treatment.

Use the search box and filters to find a trial that’s right for you.


Currently viewing trials
(Last updated: August 15, 2026)

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Radius (miles): All U.S.

20 All U.S.
Early stage    Advanced 
Treatment    Non-treatment 
Phase    I     II     III 
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Treatment

Brain Mets

BRCA1/2 (inherited)

Chemotherapy

Hormone Therapy

Leptomeningeal Disease

Radiation Oncology

Surgery

Surgery: Reconstruction

Targeted Therapy: All

Targeted Therapy: ADC

Targeted Therapy: Anti-HER2 Therapy

Targeted Therapy: CDK Inhibitors

Targeted Therapy: PARP Inhibitors

Targeted Therapy: Tumor Mutations

Targeted Therapy: Other Targeted Therapy

Vaccines and Immunotherapy

Other Treatment

Non-Treatment

Activities

Complementary and Integrative Medicine

Decision Support

Diagnosing Breast Cancer

Genetics/Family History

Having Children

Healthy/High Risk

Imaging

Lymphedema

Managing Side Effects

No Travel Required

Predicting Response to Treatment

Preventing Breast Cancer

Preventing Recurrence

Support/Education

Surveys/Interviews/Registries

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AKT

ALK

AR

BARD1

BRCA1/2 (tumor)

BRIP1

CD205

CD70

CHEK2 or CHEK1

dMMR/MSI-H

ESR1

FGFR

HER2/ERBB2

HLA

MET or C-Met

NTRK

PALB2

PIK3CA or PI3K

PTEN

RAD51

RAF (including BRAF)

RAS (KRAS or NRAS)

RB

ROS1

TP53

Click here to view online studies and trials that do not require site visits

1

NEAREST SITE: 656 miles
Vincere Cancer Center
Phoenix,AZ

VISITS: 1 visit, coincides with routine care

PHASE: NA

NCT ID: NCT07219277

Blood Test for Early Detection of Breast Cancer in Women

Clinical Validation of Early Detection Blood Test for Universal Large-scale Breast Cancer Screening to Improve Early Diagnosis for Women of All Social and Ethnic Backgrounds Scientific Title

Purpose
To study how well a blood test (the Syantra blood test) can detect breast cancer at an early stage.
Who is this for?
Women ages 30–75 who are undergoing routine breast cancer screening (mammogram, ultrasound, or MRI). You must not have a current or prior cancer diagnosis (except non-melanoma skin cancer), and must not have had breast surgery or a biopsy in the past 12 months.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be asked to do the following at your regular visit: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaire</li> <li class="seamTextUnorderedListItem">blood test</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The test analyzes a blood sample using a software program to look for signs of breast cancer. </li> <li class="seamTextUnorderedListItem">This study will also look at whether factors such as ethnicity, geography, and personal characteristics, including breast density and elevated risk, affect how well the test performs.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07219277' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.syantra.com/' target='_blank'>Syantra: Transforming Cancer Detection and Treatment</a> </li></ul>
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2

NEAREST SITE: 2539 miles
Memorial Sloan Kettering Cancer Center Basking Ridge (Limited Protocol Activities)
Basking Ridge,NJ

VISITS: 4 visits over 5 years

PHASE: NA

NCT ID: NCT07294703

Understanding Genetic and Lifestyle Factors That Affect Breast Cancer Risk

Genomic and Non-Genomic Factors Associated With Breast Cancer Risk Factors and Outcomes Scientific Title

Purpose
To understand how genetic and non‑genetic factors are associated with breast cancer risk and recurrence.
Who is this for?
Women with an abnormal finding on a breast exam or imaging test; or newly diagnosed with stage 0 (DCIS), stage I, stage II, stage III breast cancer who are planning to have surgery. Must be receiving care at Memorial Sloan Kettering (MSK).    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood and tissue samples</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The goal of this study is to understand why breast cancer risk and outcomes, including recurrence, may be different for people with different backgrounds by looking at genetic information, blood and tissue samples, and survey responses.</li> <li class="seamTextUnorderedListItem">Collecting samples of blood and tissue from patients with and without breast cancer can help determine which factors may be linked to breast cancer risk and outcomes.</li> <li class="seamTextUnorderedListItem">This is a research only study and does not provide cancer treatment.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07294703' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/types/breast-cancer/risk-and-prevention/genetic-testing.html' target='_blank'>American Cancer Society: Genetic Counseling and Testing for Breast Cancer Risk</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing for Breast Cancer</a> </li></ul>
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3

NEAREST SITE: 2693 miles
Dana Farber Cancer Institute
Boston,MA

VISITS: At least 2 visits within 4 months

PHASE: NA

NCT ID: NCT06322888

Exercise to Reduce the Risk of Breast Cancer for Women With Dense Breasts

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D) Scientific Title

Purpose
To study how exercise might lower the risk of developing breast cancer by studying changes that occur in breast tissue and blood.
Who is this for?
Women 18-59 years old with dense breasts on a mammogram within the past year and exercise less than 1 hour every week. You must not have a history of breast cancer, be pregnant or breastfeeding, or be receiving hormonal birth control or hormone replacement therapy.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, in person or virtual, 3 times every week for 3 months</li> <li class="seamTextUnorderedListItem">Exercise journal</li> <li class="seamTextUnorderedListItem">Fitbit</li> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2 : Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> followed 3 months later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, 3 months (optional)</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Greater physical activity is associated with a lower risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Exercise may change markers in blood and breast tissue that play a role in breast cancer development.</li> <li class="seamTextUnorderedListItem">If you are in group 1, the exercise program includes aerobic and resistance training exercise with a certified exercise trainer.</li> <li class="seamTextUnorderedListItem">If you are in group 1, a FitBit activity tracker, resistance bands, hand weights, and stationary bike will be provided to you. Hand weights will be returned at end of study.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06322888' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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4

No Travel Required

VISITS: No Visits Required, up to 5 months

PHASE: NA

NCT ID: NCT07320664

Alcohol Awareness Messaging to Reduce Breast Cancer Risk in Young Women

Alcohol Counter Marketing as a Breast Cancer Prevention Strategy in Young Women Scientific Title

Purpose
To test whether targeted digital messages about the link between alcohol and breast cancer risk can help reduce alcohol use and increase awareness of that risk in young women.
Who is this for?
Women who do not have breast cancer, aged 18–25 who have had at least one alcoholic drink in the past 30 days and currently live in Ohio, Michigan, Illinois, Wisconsin, or New Jersey.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Researchers want to know if digital messages, created with input from young women, can reduce how much alcohol young women drink, increase awareness that drinking alcohol raises breast cancer risk, and improve beliefs about the ability to reduce that risk by drinking less</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07320664' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.bcrf.org/about-breast-cancer/alcohol-breast-cancer-risk/' target='_blank'>Breast Cancer Research Foundation: Alcohol and Breast Cancer Risk</a> </li></ul>
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