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Find Breast Cancer Clinical Trials That Are Right For You

The clinical trials listed below are open in the U.S. for people with DCIS (stage 0), stage 1, stage 2, stage 3, or stage 4 (metastatic)
breast cancer. Clinical trials are available for people who are newly diagnosed with breast cancer, currently in treatment, experiencing
breast cancer recurrence, living with metastatic disease, as well as breast cancer survivors who have completed treatment.

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(Last updated: May 02, 2024)

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Early stage

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Phase I II III

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AKT

ALK

BARD1

BRCA1/2 (tumor)

BRIP1

CD205

CD70

CHEK2 or CHEK1

dMMR/MSI-H

ESR1

FGFR

HER2/ERBB2

HLA

MET or C-Met

NTRK

PALB2

PIK3CA or PI3K

PTEN

RAD51

RAF (including BRAF)

RAS (KRAS or NRAS)

ROS1

TP53

Click here to view online studies and trials that do not require site visits

NEAREST SITE: 3 miles
University of California, San Francisco
San Francisco,CA

VISITS: Coincides with surgery

PHASE: II

NCT ID: NCT05020574

Impact of Antibiotics on Infection and the Microbiome in People Receiving a Mastectomy

Microbiome and Association With Implant Infections: Investigating the Impact of Antibiotics on the Gut and Breast Microbiomes Post-mastectomy With Implant-based Breast Reconstruction Scientific Title

Purpose

To study the effects (good and bad) of antibiotics after mastectomy with immediate reconstruction on infection and the microbiome.

Who is this for?

Women with stage 0 (DCIS), stage I, stage II, or some stage III breast cancer or people at risk of breast cancer who are planning to receive a mastectomy with immediate reconstruction. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cephalexin (Keflex®) antibiotic, before and during surgery</li> <li class="seamTextUnorderedListItem">Cephalexin (Keflex®) antibiotic, daily for at least 7 days after surgery</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cephalexin (Keflex®) antibiotic, before and during surgery</li> <li class="seamTextUnorderedListItem">No antibiotics after surgery (unless infection occurs)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A mastectomy is surgery to remove a breast.</li> <li class="seamTextUnorderedListItem">Women with a strong family history of breast cancer or a BRCA mutation may choose to undergo a mastectomy to reduce their risk of developing breast cancer.</li> <li class="seamTextUnorderedListItem">Cephalexin (Keflex®) is an antibiotic used to prevent infection after surgery.</li> <li class="seamTextUnorderedListItem">The microbiome consists of the many bacteria, viruses, and fungi found on your body.</li> <li class="seamTextUnorderedListItem">The harmful bacteria cause disease such as infection, and the beneficial bacteria help keep you healthy.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05020574' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/surgery/mastectomy' target='_blank'>Breastcancer.org: Mastectomy</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a682733.html' target='_blank'>MedlinePlus: Cephalexin (Keflex®)</a> </li></ul>

NEAREST SITE: 3 miles
University of California San Francisco
San Francisco,CA

VISITS: Online surveys

PHASE: NA

NCT ID: NCT02620852

WISDOM Study: Women Informed to Screen Depending on Measures of Risk

Enabling a Paradigm Shift: A Preference-Tolerant RCT of Personalized vs. Annual Screening for Breast Cancer Scientific Title

Purpose

To learn if risk-based breast screening is as safe and effective as annual mammogram screening for reducing risk and detecting breast cancer.

Who is this for?

Women between the ages of 40 and 70 who have never been diagnosed with breast cancer or ductal carcinoma in situ (DCIS). Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups, or you can choose your study group. Group 1: Personalized, Risk-Based Screening <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening recommendations based on comprehensive, personal risk assessment</li> <li class="seamTextUnorderedListItem">Saliva sample genetic test</li> <li class="seamTextUnorderedListItem">Online, annual health questionnaires</li> </ul> Group 2: Standard Annual Screening <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening recommendation for annual mammograms</li> <li class="seamTextUnorderedListItem">Online, annual health questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized risk-based screening will take multiple risk factors into consideration, including genetic markers, to determine how often you should have a mammogram.</li> <li class="seamTextUnorderedListItem">This study will help researchers learn if risk-based screening, which helps women learn more about their personal breast cancer risk, is less stressful and as successful at detecting breast cancer as annual screening. </li> <li class="seamTextUnorderedListItem">This study is available in English and Spanish.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02620852' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.thewisdomstudy.org/' target='_blank'>WISDOM: Study Information Page</a> </li></ul>

NEAREST SITE: 3 miles
University of California San Francisco
San Francisco,CA

VISITS: 2 visits

PHASE: II

NCT ID: NCT04821141

Bazedoxifene and Estrogen Hormone Therapy to Reduce Risk Factors for Developing Breast Cancer

Randomized IIB Study of the Effect of Bazedoxifene Plus Conjugated Estrogens on Breast Imaging and Tissue Biomarkers in Peri or Post-Menopausal Women at Increased Risk for Development of Breast Cancer Scientific Title

Purpose

To study whether bazedoxifene and estrogen affect risk factors associated with developing breast cancer.

Who is this for?

Perimenopausal and postmenopausal women ages 45 to 60 who experience hot flashes and/or night sweats at least once a week and have a moderate risk of developing breast cancer. Risk factors include a family history of breast cancer, prior breast biopsies, or one of the following gene mutations: ATM, CDH1, CHEK2, NBN, NF1, PALB2, PTEN, STK11, P53, PTEN. You must not have a BRCA1/2 mutation. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Bazedoxifene, by mouth, daily for 6 months</li> <li class="seamTextUnorderedListItem">Estrogen, by mouth, daily for 6 months</li> <li class="seamTextUnorderedListItem">Mammogram, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Fine needle aspiration biopsy, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mammogram, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Fine needle aspiration biopsy, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> </ul> followed 6 months later by (optional): <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Bazedoxifene, by mouth, daily for 6 months</li> <li class="seamTextUnorderedListItem">Estrogen, by mouth, daily for 6 months</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Bazedoxifene is a type of hormone therapy called a selective estrogen receptor modulator (SERM). SERMs work by blocking the activity of estrogen. It may help reduce the risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Estrogen is a hormone used to treat women experiencing hot flashes.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04821141' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2022-03864&r=1#:~:text=Giving%20bazedoxifene%20with%20conjugated%20estrogens,increased%20risk%20for%20breast%20cancer.' target='_blank'>National Cancer Institute: Trial Information Page</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a614004.html' target='_blank'>Medline Plus: Bazedoxifene and Estrogen</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/mammograms.htm' target='_blank'>Centers for Disease Control and Prevention: Mammogram</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/breast-cancer/screening-tests-and-early-detection/breast-biopsy/fine-needle-aspiration-biopsy-of-the-breast.html#:~:text=During%20a%20fine%20needle%20aspiration,needle%20biopsy%20is%20often%20preferred).' target='_blank'>American Cancer Society: Fine Needle Aspiration Biopsy</a> </li></ul>

NEAREST SITE: 3 miles
UCSF Medical Center-Mount Zion
San Francisco,CA

VISITS: 1 visit every 6 months for 5 years

PHASE: III

NCT ID: NCT04711109

Denosumab to Prevent Breast Cancer in Women With an Inherited BRCA1 Mutation

BRCA-P: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, International Phase 3 Study to Determine the Preventive Effect of Denosumab on Breast Cancer in Women Carrying a BRCA1 Germline Mutation Scientific Title

Purpose

To study the safety, effects (good and bad), and ability of denosumab to prevent breast cancer.

Who is this for?

Women aged 25 to 55 who do not have breast cancer and who have an inherited BRCA1 mutation. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Denosumab, by injection, every 6 months for up to 5 years</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for denosumab, by injection, every 6 months for up to 5 years</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Denosumab is a targeted therapy called a RANK ligand inhibitor. It is used to reduce the risk of bone fractures in people without cancer and to reduce new bone growth in people whose cancer has spread to their bones.</li> <li class="seamTextUnorderedListItem">Denosumab may also reduce the risk of developing breast cancer in women with an inherited (germline) BRCA1 mutation.</li> <li class="seamTextUnorderedListItem">Targets or mutations: BRCA1, BRCA 1</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04711109' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancerpreventioninitiative.org/projects/prevention-of-breast-cancer-by-denosumab-in-women-carrying-a-brca1-or-brca2-mutation-brca-p-trial/' target='_blank'>Cancer Prevention Initiative: Trial Information Page</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a610023.html' target='_blank'>MedlinePlus: Denosumab</a> </li></ul>

NEAREST SITE: 8 miles
Bay Area Breast Surgeons Inc
Emeryville,CA

VISITS: 2 visits in 1 year

PHASE: NA

NCT ID: NCT05334069

Collecting Blood Samples From People With and Without Breast Cancer to Evaluate Tests for Early Cancer Detection

Blinded Reference Set for Multicancer Early Detection Blood Tests Scientific Title

Purpose

To collect blood and tissue samples from people with breast cancer and people without breast cancer to evaluate tests for early cancer detection.

Who is this for?

People 40-75 years old with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have not yet received treatment, or who do not have breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide blood samples, 2 times</li> <li class="seamTextUnorderedListItem">Provide tissue samples (for people with cancer), 2 times</li> <li class="seamTextUnorderedListItem">Complete questionnaires, 2 times</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Collecting and storing samples of blood and tissue from patients with and without breast cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05334069' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis' target='_blank'>National Cancer Institute: How Cancer Is Diagnosed</a> </li></ul>

NEAREST SITE: 27 miles
Stanford University School of Medicine
Stanford,CA

VISITS: 1 visit

PHASE: NA

NCT ID: NCT01034033

A Study of How Cancer Develops in Women With BRCA1/2 or Other Genetic Mutations

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples Scientific Title

Purpose

To analyze blood samples from women at high risk of developing breast cancer in order to learn more about how cells change over time from normal to cancerous.

Who is this for?

Women at high-risk for developing breast cancer. Full eligibility criteria

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All participants will provide blood samples.
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">BRCA1 and BRCA2 are tumor suppressor genes.</li> <li class="seamTextUnorderedListItem">Inheriting a mutation in the BRCA1 or BRCA2 gene increases cancer risk. </li> <li class="seamTextUnorderedListItem">For the cancer to develop, though, the cells will need to first acquire other mutations.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT01034033' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://stanfordhealthcare.org/medical-conditions/cancer/hboc/brca-1-and-2.html' target='_blank'>Stanford: About Hereditary Breast Ovarian Cancer Syndrome</a> </li><li class='seamTextUnorderedListItem'><a href='https://clinicaltrials.gov/ct2/show/NCT01034033?term=NCT01034033&rank=1' target='_blank'>ClinicalTrials.gov trial info</a> </li></ul>

NEAREST SITE: 336 miles
UCLA Kaiser Permanente Center for Health Equity
Los Angeles,CA

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05298605

Faith in Action: Church-Based Education and Navigation to Increase Breast Cancer Screening in Korean Women

Faith in Action! A Cluster-Randomized Trial to Evaluate the Efficacy of a Church-based Navigation Model to Increase Breast Cancer Screening Among Korean Women in Los Angeles Scientific Title

Purpose

To study if the Faith in Action cancer screening education and navigation curriculum increases breast cancer screening among Korean American women.

Who is this for?

Korean women at least 45 years old who do not have breast cancer, have not received a screening mammogram in the last 2 years, and are members of participating Korean churches in Los Angeles, California. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Faith in Action cancer screening education and navigation curriculum</li> <li class="seamTextUnorderedListItem">American Cancer Society Screening Guidelines pamphlet</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> Group 2: Standard of Care <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Presentation on physical activity and nutrition</li> <li class="seamTextUnorderedListItem">American Cancer Society Screening Guidelines pamphlet</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Faith in Action is a curriculum designed to deliver cancer education and increase motivation to participate in breast cancer screening through proven approaches such as one-on-one education, small media, and workshops.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05298605' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ucla.clinicaltrials.researcherprofiles.org/trial/NCT05298605' target='_blank'>UCLA: Faith in Action</a> </li></ul>

NEAREST SITE: 348 miles
Los Angeles County-USC Medical Center
Los Angeles,CA

VISITS: 1 visit

PHASE: I

NCT ID: NCT06171607

Contrast-Enhanced Ultrasound to Identify Breast Masses

Characterizing Breast Masses Using an Integrative Framework of Machine Learning and Radiomics Scientific Title

Purpose

To learn if using contrast-enhanced ultrasound (CEUS) will help to determine if an ultrasound-guided biopsy is necessary.

Who is this for?

Women who are planning to receive an ultrasound-guided biopsy. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast-enhanced ultrasound (CEUS) scan with Lumason or DEFINITY contrast agent, by IV, 1 time</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasounds use sound waves to produce images of structures within your body without using radiation. Ultrasounds are widely used to diagnose many diseases in the body.</li> <li class="seamTextUnorderedListItem">A contrast-enhanced ultrasound (CEUS) is an ultrasound given with a contrast agent that helps improve images obtained from the scan.</li> <li class="seamTextUnorderedListItem">In this trial, Lumason and Perflutren are the contrast agents.</li> <li class="seamTextUnorderedListItem">The scan will take 1-1.5 hours.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06171607' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/breast-biopsy' target='_blank'>Breastcancer.org: Breast Biopsies</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/drugs-supplements/perflutren-lipid-microsphere-intravenous-route/side-effects/drg-20067608?p=1' target='_blank'>Mayo Clinic: Perflutren Ultrasound Contrast Agent</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/drugs-supplements/sulfur-hexafluoride-lipid-type-a-microspheres-injection-route-intravenous-route/side-effects/drg-20405988?p=1' target='_blank'>Mayo Clinic: Lumason Ultrasound Contrast Agent</a> </li></ul>

NEAREST SITE: 660 miles
Mayo Clinic in Arizona
Scottsdale,AZ

VISITS: 1 visit

PHASE: NA

NCT ID: NCT06112795

Studying Beliefs About Breast Cancer Risk and Screening Among Hispanic Women in Arizona

Exploring Cultural Acceptability of Community Breast Cancer Risk Assessment Among Hispanic Women in Maricopa County Scientific Title

Purpose

To study attitudes, beliefs, and barriers about breast cancer risk and mammogram breast cancer screening among Hispanic women in Maricopa County, Arizona.

Who is this for?

Hispanic women 40-65 years old who live in Maricopa County, Arizona and have not had breast cancer. You must either have health insurance through the Arizona Health Care Cost Containment System or not have health insurance. Full eligibility criteria

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You will complete the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Attend an interview or focus group, 1 time</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Hispanic women have fewer mammograms than non-Hispanic white women.</li> <li class="seamTextUnorderedListItem">Education about the importance of breast cancer screening may improve outcomes of Hispanic women.</li> <li class="seamTextUnorderedListItem">This trial is available in English and Spanish.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06112795' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cedars-sinai.org/blog/breast-cancer-risks-latinas.html' target='_blank'>Cedars Sinai: Hispanic Women and Breast Cancer</a> </li></ul>

NEAREST SITE: 660 miles
Mayo Clinic in Arizona
Scottsdale,AZ

VISITS: 1 visit

PHASE: NA

NCT ID: NCT06036875

Survey to Understand How Black and Hispanic Women Perceive Their Risk for Breast Cancer

CARE: Cancer Risk Perception and Women of Color Scientific Title

Purpose

To study how Black and Hispanic women understand their current and lifetime risk for breast cancer.

Who is this for?

Women, age 25-50 years, who are Black and/or Hispanic and who live in Arizona or Florida with no history of breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Survey, 1 time</li> <li class="seamTextUnorderedListItem">Interview (optional)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is examining the relationship between risk factors for breast cancer and a person's perceptions of those risk factors and if these relationships are different according to race and ethnicity.</li> <li class="seamTextUnorderedListItem">This study is also exploring how people reduce their risk for breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06036875' target='_blank'>ClinicalTrials.gov</a> </li></ul>

NEAREST SITE: 660 miles
Mayo Clinic in Arizona
Scottsdale,AZ

VISITS: Number of visits unavailable

PHASE: II

NCT ID: NCT05557877

Low-Dose Aspirin to Prevent Breast Cancer After Having a Baby

Targeted Prevention of Postpartum-Related Breast Cancer Scientific Title

Purpose

To study whether low-dose aspirin prevents breast cancer in women who have recently had a baby and who have benign (non-cancerous) breast disease.

Who is this for?

Pre-menopausal women, ages 18 to 45, who have had a baby in the last 5 years, have received a mammogram that suggested benign (non-cancerous) breast disease, and are planning to receive a biopsy. You must not be taking any medication to prevent breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biopsy</li> <li class="seamTextUnorderedListItem">Blood tests</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Low-dose aspirin, by mouth, daily</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood tests</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> Please contact research site for treatment schedule
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Low-dose aspirin, a non-steroidal anti-inflammatory drug, may reduce inflammation in blood and tissue which may prevent breast cancer after having a baby.</li> <li class="seamTextUnorderedListItem">Benign breast disease is non-cancerous breast disease.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05557877' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-minute-aspirins-role-in-preventing-and-stopping-the-spread-of-cancer/' target='_blank'>Mayo Clinic: Aspirin and Cancer Prevention</a> </li></ul>

NEAREST SITE: 744 miles
Center for Indigenous Health
Whiteriver,AZ

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05665660

Culturally Relevant Education and Coaching to Improve Breast Cancer Screening in American Indian or Alaska Native Women

Developing and Evaluating Scalable and Culturally Relevant Interventions to Improve Breast Cancer Screening Among White Mountain Apache Women Scientific Title

Purpose

To study ways to promote breast cancer screening among women in the White Mountain Apache community.

Who is this for?

American Indian or Alaska Native women who live on or within 60 miles of the Fort Apache Indian Reservation. You must not have had a mammogram in the last year or have a personal history of breast cancer. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">CARE: Complete mammogram education course</li> <li class="seamTextUnorderedListItem">COACH: Access to an Apache women's health coach</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">CARE: Complete mammogram education course</li> </ul> followed 3 months later by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">COACH: Access to an Apache women's health coach (optional)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">CARE refers to a mammogram education course.</li> <li class="seamTextUnorderedListItem">COACH refers to access to an Apache women's health coach and navigator who will help you receive breast cancer screening.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05665660' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://americanindiancancer.org/aicaf-project/breast-cancer-awareness/' target='_blank'>American Indian Cancer Foundation: Breast Cancer in American Indian Women</a> </li><li class='seamTextUnorderedListItem'><a href='https://ascopost.com/news/march-2023/regardless-of-income-american-indiannative-american-women-may-be-less-likely-to-undergo-mammography-than-white-women/' target='_blank'>ASCO Post: American Indian Women and Mammography</a> </li></ul>

NEAREST SITE: 804 miles
Bozeman Health Deaconess Hospital
Bozeman,MT

VISITS: One visit every year

PHASE: NA

NCT ID: NCT02012699

iCaRe2: Integrated Cancer Data Repository for Cancer Research

Integrated Cancer Repository for Cancer Research Scientific Title

Purpose

To study cancer risk factors, cancer prevention, early detection and personalized cancer treatments by creating a data registry and biobank.

Who is this for?

People who have or are at risk for developing breast cancer and other cancers. Full eligibility criteria

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This is a data collection (registry) study. You will: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide biospecimens (blood, urine, tissue) for the biobank</li> <li class="seamTextUnorderedListItem">Complete questionnaires, once a year</li> <li class="seamTextUnorderedListItem">Participate in follow-up visits with your healthcare provider, once a year</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Research sites will implement and maintain a comprehensive data and biospecimen bank known as the Integrated Cancer Repository for Cancer Research (iCaRe2). </li> <li class="seamTextUnorderedListItem">Participants will provide blood, urine and tissue samples for the biobank. </li> <li class="seamTextUnorderedListItem">The data registry and biospecimen bank is made available for research on cancer and other chronic diseases.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02012699' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://icare2project.org' target='_blank'>iCaRe2 Project</a> </li></ul>

NEAREST SITE: 941 miles
University of Colorado Hospital
Aurora,CO

VISITS: Coincides with surgery

PHASE: NA

NCT ID: NCT04558138

Mastectomy with Immediate Reconstruction With or Without Spending the Night in the Hospital

A Randomized Controlled Trial in Patients Undergoing Immediate Implant-Based Breast Reconstruction Utilizing an Enhanced Recovery Pathway Comparing Outcomes and Patient Satisfaction Based on Time of Discharge Scientific Title

Purpose

To study the effects (good and bad) of spending the night in the hospital compared to not spending the night in the hospital for women receiving a mastectomy with immediate reconstruction.

Who is this for?

Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women at risk of developing breast cancer who are planning to receive a mastectomy with immediate reconstruction at University of Colorado Anschutz Medical Campus or Highlands Ranch Campus. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Not Spending the Night in the Hospital <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Released from hospital the day of surgery</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times in 1 week</li> </ul> Group 2: Spending the Night in the Hospital <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Released from hospital the day after surgery</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times in 1 week</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Traditionally people undergoing a mastectomy with immediate reconstruction are admitted to the hospital overnight.</li> <li class="seamTextUnorderedListItem">This trial will study whether discharge on the same day of surgery poses any major risks compared to discharge the day after surgery.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04558138' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/surgery/mastectomy' target='_blank'>Breastcancer.org: Mastectomy</a> </li></ul>

NEAREST SITE: 1500 miles
University of Kansas Medical Center
Kansas City,KS

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT00291096

Assessment of Individual Risk in High-Risk Women

High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer Scientific Title

Purpose

To develop a system of breast cancer risk assessment as well as to determine the best biomarkers (biological markers) for predicting and monitoring response to prevention interventions.

Who is this for?

Women aged 30 to 65 with at least 2 times the normal risk of developing breast cancer. Full eligibility criteria

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All participants will undergo the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood tests</li> <li class="seamTextUnorderedListItem">Tissue samples</li> <li class="seamTextUnorderedListItem">Mammogram </li> <li class="seamTextUnorderedListItem">Random periareolar fine needle aspiration (RPFNA)</li> <li class="seamTextUnorderedListItem">Possible genetic testing</li> </ul> This is a prospective study, in which the researchers will be in contact with you for a number of years after you undergo initial testing and will want to know if you go on to develop breast cancer.
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Doctors are trying to determine the best protocols for following women who are known to be at high risk for developing breast cancer.</li> <li class="seamTextUnorderedListItem">The doctors will evaluate many factors, including new breast tissue biomarkers, mammographic breast density, blood levels of estrogens, proteins found in breast cells and nipple fluid, and hormone levels.</li> <li class="seamTextUnorderedListItem">This is a prospective study. This means the researchers will maintain contact with the research participants for a number of years, as they are interested in knowing who goes on to develop breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT00291096' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/breast-cancer/risk-and-prevention.html' target='_blank'>American Cancer Society: Risk Factors</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/risk' target='_blank'>BreastCancer.org: Your Risk</a> </li></ul>

NEAREST SITE: 1509 miles
UT Southwestern
Dallas,TX

VISITS: Coincides with surgery

PHASE: NA

NCT ID: NCT05245812

Robotic Nipple Sparing Mastectomy for Women with DCIS, Stage I-III Breast Cancer, or at High Risk for Breast Cancer

Safety and Feasibility of Robotic Single-port (SP) Nipple Sparing Mastectomy: A Single Institution, Single Arm Pilot Trial Scientific Title

Purpose

To study the safety and effects (good and bad) of nipple sparing mastectomy with da Vinci single port (SP) Surgical System.

Who is this for?

Women with DCIS, stage I, stage II, or some stage III breast cancer, or at high risk for breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Nipple sparing mastectomy with da Vinci single port (SP) Surgical System</li> <li class="seamTextUnorderedListItem">Immediate breast reconstruction with tissue expanders/implants and acellular dermal matrix (Alloderm®)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A mastectomy is surgery to remove a breast.</li> <li class="seamTextUnorderedListItem">A nipple sparing mastectomy (NSM) leaves most of the healthy breast skin, including the nipple.</li> <li class="seamTextUnorderedListItem">The da Vinci single port (SP) Surgical System is an experimental surgery system designed for surgeons to perform minimally invasive surgery, such as nipple sparing mastectomy.</li> <li class="seamTextUnorderedListItem">The da Vinci SP Surgical System is approved for use during other surgeries.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05245812' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.intuitive.com/en-us/patients/procedures/general-surgery##' target='_blank'>Intuitive Surgical Device Information Page: Da Vinci Surgical System</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cedars-sinai.org/health-library/diseases-and-conditions/n/nipple-sparing-mastectomy.html' target='_blank'>Cedars-Sinai: Nipple Sparing Mastectomy</a> </li></ul>

NEAREST SITE: 1562 miles
Namida Lab
Fayetteville,AR

VISITS: 1 visit

PHASE: NA

NCT ID: NCT05268224

Melody® Test Using Tears to Screen Women With Dense Breast Tissue for Breast Cancer

Investigation of Melody®, a Lab Developed Test for Breast Cancer, as a Supplemental Tool to Current Screening Recommendations for Women With Dense Breast Tissue. Scientific Title

Purpose

To study the ability of the Melody® test to use tears to screen women with dense breast tissue for breast cancer.

Who is this for?

Women with dense breast tissue who have not been diagnosed with breast cancer. Full eligibility criteria

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You will complete the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide tears sample for Melody® test</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A biomarker is a gene, protein, or molecule produced by the body or tumor in a person with cancer that tells a doctor something about the cancer cells.</li> <li class="seamTextUnorderedListItem">Biomarkers can be identified from tumor, blood, tears, and other samples.</li> <li class="seamTextUnorderedListItem">The Melody® test identifies biomarkers in your tears to screen women with dense breasts for breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05268224' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://auria.care/' target='_blank'>Namida Lab: Auria Test Using Tears for Breast Cancer Screening</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mana.md/melody/' target='_blank'>Medical Associates of Northwest Arkansas: Melody® Test</a> </li></ul>

NEAREST SITE: 1615 miles
Mayo Clinic in Rochester
Rochester,MN

VISITS: 1-2 visits within 6 months

PHASE: NA

NCT ID: NCT06058650

Molecular Breast Imaging to Guide Biopsy

Pilot Clinical Study to Evaluate Molecular Breast Imaging- Guidance for Sampling of Breast Abnormalities Scientific Title

Purpose

To study how well molecular breast imaging (MBI) helps guide the collection of cells during a breast biopsy.

Who is this for?

Women who previously received breast imaging with mammography, ultrasound, MRI, or molecular breast imaging (MBI). Full eligibility criteria

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You will be assigned to 1 of 2 groups: Group 1: Biopsy Not Recommended or Previous Imaging/Biopsy Showed Benign (Normal) Results <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI), 1 time</li> </ul> Group 2: Biopsy Recommended <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI), 1 time</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast biopsy</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Collection of abnormal cells during a biopsy is often guided by either ultrasound or mammography in order to ensure that a sample of the correct part of the breast is taken.</li> <li class="seamTextUnorderedListItem">Sometimes abnormal tissue cannot be seen on ultrasound or mammography, and therefore, a biopsy guided with ultrasound or mammography may not always be accurate.</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI) is a method for detecting abnormal cells on a scan that uses injection of a radioactive tracer. Breast cancer cells take up this tracer more than normal cells, and this allows doctors to see the cancer cells on a scan.</li> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi is the tracer used in this study.</li> <li class="seamTextUnorderedListItem">MBI may improve the detection of some breast tumors.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06058650' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/molecular-breast-imaging' target='_blank'>Breastcancer.org: Molecular Breast Imaging</a> </li></ul>

NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05667532

Contrast-Enhanced Mammograms for Women with Dense Breasts

The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts Scientific Title

Purpose

To compare the ability of contrast-enhanced mammography (CEM) and standard mammography to detect breast cancer in women with dense breasts.

Who is this for?

Women ages 30 to 75 with dense breasts and no personal history of DCIS or breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast-enhanced mammogram</li> </ul> Please contact research site for treatment schedule
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard mammography (mammogram) is a breast cancer screening procedure involving taking an X-ray picture of the breast.</li> <li class="seamTextUnorderedListItem">Contrast-enhanced mammography (CEM) includes an injection of contrast dye before the mammogram to detect and visualize cancer cells.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05667532' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://uvahealth.com/services/breast-screening/cem' target='_blank'>University of Virginia Health: Contrast-Enhanced Mammogram</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/mammograms.htm' target='_blank'>Centers for Disease Control and Prevention: Mammogram</a> </li></ul>

NEAREST SITE: 1643 miles
The University of Texas Health Science Center at Houston
Houston,TX

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT06082882

Increasing Breast Cancer Screening in Latina Women in Texas

A Community Based Program to Increase Breast and Cervical Cancer Screening and HPV Vaccination to Reduce the Impact of Breast and Cervical Cancer Among Latinas. (SEMM2) Scientific Title

Purpose

To study the ability of the Salud en Mis Manos program to increase breast cancer screening in Latina women in Texas.

Who is this for?

Latina women at least 40 years old who have not received a mammogram in the last 2 years and do not have a history of any cancer. You must live in Texas. Full eligibility criteria

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You will receive the following through the Salud en Mis Manos program: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer screening education; in-person, by phone, or by Zoom</li> <li class="seamTextUnorderedListItem">Breast cancer screening navigation</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial also includes cervical cancer screening.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06082882' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://sph.uth.edu/research/centers/chppr/research/project.htm?project=f3a87036-9372-431c-9e86-b789c65b06d6' target='_blank'>UTHealth Houston: Salud en Mis Manos (SEMM)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/screening.htm' target='_blank'>Centers for Disease Control and Prevention: Breast Cancer Screening</a> </li></ul>

NEAREST SITE: 1643 miles
MD Anderson Cancer Center
Houston,TX

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05694559

Inherited Cancer Genetic Testing for Black Individuals and Families

Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics Scientific Title

Purpose

To connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.

Who is this for?

Black or African-American individuals over 18 years of age that live near Houston, Texas. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saliva collection kit to collect a saliva sample for genetic testing</li> <li class="seamTextUnorderedListItem">Screening form to assess your risk of hereditary breast cancer</li> <li class="seamTextUnorderedListItem">Counseling about genetic testing</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing looks for changes, sometimes called mutations or variants, in your DNA.</li> <li class="seamTextUnorderedListItem">You will also receive counseling about what genetic testing is, why you are eligible, how to receive genetic testing, and that you will be connected to a genetic counselor if you have a pathogenic mutation (PV) of a variant of unknown significance (VUS).</li> <li class="seamTextUnorderedListItem">You will also receive resources for family cascade genetic testing.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05694559' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/risk-factor/gene-mutations-genetic-testing/genetic-counseling-for-people-who-do-not-have-breast-cancer/' target='_blank'>Susan G. Komen: Genetic Testing for People Who Do Not Have Breast Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/genomics/disease/cascade_testing/index.htm' target='_blank'>Centers for Disease Control and Prevention: Cascade Testing</a> </li></ul>

NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX

VISITS: 1 visit

PHASE: NA

NCT ID: NCT04671498

Droplet-BC Blood Test to Detect Breast Cancer

Detection by Circulating RNA With Optimized Machine Learning Technology for Breast Cancer: DROPLET-BC Study Scientific Title

Purpose

To determine whether the Droplet-BC test can distinguish blood samples from people with breast cancer from people without breast cancer, which may provide a new method to screen for and diagnose breast cancer.

Who is this for?

People newly diagnosed with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have not yet received treatment, and people that do not have breast cancer. Full eligibility criteria

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You will provide the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood sample for Droplet-BC test</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Droplet-BC test analyzes RNA in blood samples which may be used to screen for and diagnose breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04671498' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.preferred-medicine.com/technology' target='_blank'>Preferred Medicine: Droplet-BC Test</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.preferred-medicine.com/clinical-study' target='_blank'>Preferred Medicine: Trial Information Page</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2021-03585' target='_blank'>National Cancer Institute: Trial Information Page</a> </li></ul>

NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05649072

Genetic Testing and Counseling for Women in Texas

Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics. Scientific Title

Purpose

To provide genetic testing and counseling to underserved women at risk for breast cancer.

Who is this for?

Women ages 40 to 74 who live in Texas, do not have health insurance, and are planning to receive a mammogram through the Project VALET program. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing and counseling</li> <li class="seamTextUnorderedListItem">Questionnaire</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will provide a saliva sample for genetic testing when you arrive at your Project VALET mammogram appointment.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05649072' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mdanderson.org/about-md-anderson/business-legal/office-of-health-policy/project-valet.html#:~:text=Project%20VALET%20(Providing%20Valuable%20Area,are%20patients%20in%20participating%20clinics.' target='_blank'>MD Anderson Cancer Center: Project VALET Mammogram Screening</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing</a> </li></ul>

NEAREST SITE: 1853 miles
Mile Square Health Center
Chicago,IL

VISITS: 3 visits

PHASE: NA

NCT ID: NCT05841355

Empowering Latina Women to Receive Breast Cancer Screening

Empowering Latinas to Obtain Guideline Concordant Screenings Scientific Title

Purpose

This trial will study a new way to educate Latina women about the importance of breast cancer screening.

Who is this for?

Latina women 50-74 years old who have not had a mammogram in the last 2 years and have not been diagnosed with breast cancer. Full eligibility criteria

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What's being studied?
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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">New breast cancer screening education, 3 sessions</li> </ul> Group 2: Control <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard breast cancer screening education, 3 sessions</li> </ul> Please contact research site for trial schedule
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Latina women are less likely than other groups to receive breast cancer screening.</li> <li class="seamTextUnorderedListItem">Education sessions cover topics such as breast cancer information, screening, personal stories, lifestyle factors, role playing, and individual action plans.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05841355' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.bcrf.org/blog/hispanic-latina-breast-cancer-facts-statistics/' target='_blank'>Breast Cancer Research Foundation: Breast Cancer and Screening in Latina Women</a> </li></ul>

NEAREST SITE: 1853 miles
University of Illinois at Chicago Hospital and Ambulatory Clinics
Chicago,IL

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT04378751

Promoting Genetic Counseling Among African American Women at High Risk for Breast Cancer

Promoting Genetic Counseling Among African American Women With a Family History of Breast Cancer Scientific Title

Purpose

To study the ability of a genetic counseling video to promote genetic counseling among African American women at high risk for breast cancer.

Who is this for?

African American women at least 25 years old who are at high risk for developing breast cancer and have not received genetic counseling. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Watch a genetic counseling video</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times</li> </ul> Group 2: Control <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Review a genetic counseling informational brochure</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic counseling can identify people at high risk for breast cancer and can help personalize prevention.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04378751' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing for Breast Cancer Risk</a> </li><li class='seamTextUnorderedListItem'><a href='https://medicine.wustl.edu/news/african-american-breast-cancer-patients-less-likely-to-receive-genetic-counseling-testing/' target='_blank'>Washington University School of Medicine: African American Women and Genetic Counseling</a> </li></ul>

NEAREST SITE: 1854 miles
AMITA Health Saint Joseph Chicago
Chicago,IL

VISITS: Coincides with surgery

PHASE: II

NCT ID: NCT05554211

Tranexamic Acid to Reduce Drainage After Bilateral Mastectomy

Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage Scientific Title

Purpose

To study the safety and ability of tranexamic acid to reduce drainage after a bilateral mastectomy.

Who is this for?

Women who are planning to receive a bilateral mastectomy to reduce their risk of developing breast cancer and women with DCIS, stage I, stage II, or some stage III breast cancer who are planning to receive a bilateral mastectomy. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Tranexamic acid, by skin</li> <li class="seamTextUnorderedListItem">Gentamicin</li> </ul> Group 2: Standard Treatment <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo (saline) for tranexamic acid, by skin</li> <li class="seamTextUnorderedListItem">Gentamicin</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A bilateral mastectomy is surgery to remove both breasts.</li> <li class="seamTextUnorderedListItem">Women with a strong family history of breast cancer or a BRCA mutation may choose to undergo a bilateral mastectomy to reduce their risk of developing breast cancer.</li> <li class="seamTextUnorderedListItem">Drains help remove fluid build up in the area where the breast is removed.</li> <li class="seamTextUnorderedListItem">Tranexamic acid is an FDA approved drug that promotes blood clotting by preventing the breakdown of blood clots that your body naturally forms.</li> <li class="seamTextUnorderedListItem">Tranexamic acid is commonly used to control bleeding in a variety of surgeries and is available in injection or oral forms. However, because it is not currently FDA approved for use in elective breast surgery, this drug is considered experimental in this study. </li> <li class="seamTextUnorderedListItem">Gentamicin is an antibiotic used to prevent infection after surgery.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05554211' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://moffitt.org/cancers/breast-cancer/treatment/bilateral-mastectomy/' target='_blank'>Moffitt Cancer Center: Bilateral Mastectomy</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a612021.html' target='_blank'>Medline Plus: Tranexamic Acid</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.verywellhealth.com/managing-your-surgical-drains-following-breast-surgery-4021630' target='_blank'>Verywell Health: Surgical Drains After Breast Surgery</a> </li></ul>

NEAREST SITE: 1857 miles
University of Chicago
Chicago,IL

VISITS: 1 visit

PHASE: NA

NCT ID: NCT03238976

Nature Sounds to Reduce Pain and Anxiety During a Breast Core Needle Biopsy

Nature Sounds as a Pain and Anxiety Reducing Strategy in Patients Undergoing Breast Core Biopsy: A Randomized Study Scientific Title

Purpose

To investigate the effects (good and bad) playing continuous nature sounds during a core needle biopsy has on a patient's pain and anxiety.

Who is this for?

Women scheduled to have a breast core needle biopsy. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive continuous nature sounds during core needle biopsy</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive supportive dialogue during core needle biopsy</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A core needle biopsy is a procedure that removes a small amount of suspicious tissue from the breast with a needle.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03238976' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ww5.komen.org/BreastCancer/CoreNeedleBiopsy.html' target='_blank'>Susan G. Komen: Core Needle Biopsy</a> </li></ul>

NEAREST SITE: 1958 miles
Vanderbilt University Medical Center
Nashville,TN

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05051631

Personalized Education to Increase Breast Cancer Risk Assessment

BRAVE Strategy - Breast Cancer Risk Assessment -achieVing Equity Scientific Title

Purpose

To study personalized ways to increase assessment of breast cancer risk.

Who is this for?

Women 25-49 years old who have not been diagnosed with breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized education about breast cancer risk, for 4 months</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Many factors affect the risk of developing breast cancer.</li> <li class="seamTextUnorderedListItem">Understanding breast cancer risk is important for making decisions about screening.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05051631' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://healthlibrary.vanderbilthealth.com/42,BreastCancerRisk' target='_blank'>Vanderbilt University: Breast Cancer Risk Assessment</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/risk_factors.htm' target='_blank'>Centers for Disease Control and Prevention: Risk Factors for Breast Cancer</a> </li></ul>

NEAREST SITE: 2054 miles
Rogel Cancer Center
Ann Arbor,MI

VISITS: 1 visit

PHASE: NA

NCT ID: NCT06043661

TriNetra Blood Test for Early Detection of Breast Cancer

An Evaluation of a Circulating Tumor Cell-based Test (TriNetra™-Breast) for Breast Cancer Screening in Women Aged 40 and Above Scientific Title

Purpose

To study the usefulness and safety of the TriNetra Breast test for breast cancer screening.

Who is this for?

Women at least 40 years old who have not been diagnosed with any cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood sample for TriNetra Breast test</li> <li class="seamTextUnorderedListItem">Mammogram</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biopsy (if needed)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The TriNetra Breast test is a blood test that may detect breast cancer at very early stages.</li> <li class="seamTextUnorderedListItem">The TriNetra Breast test identifies circulating tumor cells (CTCs) associated with breast cancer.</li> <li class="seamTextUnorderedListItem">Your TriNetra Breast results will be compared to your mammogram and biopsy (if relevant) results.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06043661' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://trinetra360.com/' target='_blank'>Datar Cancer Genetics: TriNetra Breast Test</a> </li></ul>

NEAREST SITE: 2054 miles
University of Michigan Rogel Cancer Center
Ann Arbor,MI

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05700006

Effects of Hormone Therapy vs. No Hormone Therapy for Breast Cancer and Breast Cancer Prevention on Aging and the Microbiome

An Observational Study of Women With Breast Cancer Examining the Effect of Endocrine Therapy on Aging Scientific Title

Purpose

To study the effects of hormone therapy on biomarkers of aging and the microbiome.

Who is this for?

Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women at high risk of developing breast cancer. You must not have received treatment with an aromatase inhibitor for breast cancer or breast cancer prevention. Full eligibility criteria

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You will be assigned to 1 of 3 groups depending on your situation: Group 1: Over 65 and Planning to Receive Hormone Therapy <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Physician's choice of anastrozole (Arimidex®), exemestane (Aromasin®), or letrozole (Femara®)</li> <li class="seamTextUnorderedListItem">3 stool samples, questionnaires, blood draws</li> </ul> Group 2: Over 65 and Not Planning to Receive Hormone Therapy (Control Group) <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">3 stool samples, questionnaires, blood draws</li> </ul> Group 3: Under 65 and Planning to Receive Hormone Therapy <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Physician's choice of anastrozole (Arimidex®), exemestane (Aromasin®), or letrozole (Femara®)</li> <li class="seamTextUnorderedListItem">3 stool samples, questionnaires, blood draws</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The microbiome is the collection of microorganisms (bacteria) living in your digestive tract.</li> <li class="seamTextUnorderedListItem">Anastrozole (Arimidex®), exemestane (Aromasin®), and letrozole (Femara®) are types of hormone therapy called aromatase inhibitors. Aromatase inhibitors block some production of estrogen that helps cancer grow.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05700006' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy/arimidex' target='_blank'>Breastcancer.org: Anastrozole (Arimidex®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy/aromasin' target='_blank'>Breastcancer.org: Exemestane (Aromasin®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy/femara' target='_blank'>Breastcancer.org: Letrozole (Femara®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.insideprecisionmedicine.com/topics/oncology/breast-cancer/probiotic-bacteria-may-improve-efficacy-of-endocrine-targeted-therapies-for-breast-cancer/' target='_blank'>Inside Precision Medicine: Breast Cancer Treatments and the Microbiome</a> </li></ul>

NEAREST SITE: 2193 miles
Cleveland Clinic, Case Comprehensive Cancer Center
Cleveland,OH

VISITS: 1 visit

PHASE: NA

NCT ID: NCT04348123

Providing Screening Mammograms to Women Experiencing Homelessness in Cleveland, Ohio

A Proposed Community-Based Interventional Program That Educates, Identifies And Overcomes Barriers to Complete Screening Mammography Among Homeless Women Scientific Title

Purpose

To provide mammograms to increase screening rates and decrease late-stage breast cancer diagnoses in women who are experiencing homelessness.

Who is this for?

Women who have not had a mammogram in the last year and are residents at a homeless shelter or transitioning housing facility near Cleveland, Ohio. Full eligibility criteria

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You will complete the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Attend education session about breast health and mammograms</li> <li class="seamTextUnorderedListItem">Receive mammogram (optional)</li> <li class="seamTextUnorderedListItem">Complete survey</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The education sessions will explain breast health, mammography, and screening options and address common barriers.</li> <li class="seamTextUnorderedListItem">Mammograms use X-rays to screen for breast cancer.</li> <li class="seamTextUnorderedListItem">In this trial, the mammograms are optional and will be provided at no cost (free).</li> <li class="seamTextUnorderedListItem">Spanish speaking staff will be available for the educational sessions.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04348123' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/mammograms' target='_blank'>Breastcancer.org: Mammograms</a> </li></ul>

NEAREST SITE: 2299 miles
Roswell Park Cancer Institute
Buffalo,NY

VISITS: 1 visit

PHASE: NA

NCT ID: NCT03897270

Photoacoustic Imaging (A Scan That Uses Waves and Light) to Study Breast Tissue and Tumors in Women

Photoacoustic Imaging of Human Breast Scientific Title

Purpose

To study breast tissue and tumors by using photoaccoustic imaging (a type of scan that uses sound and light to study tissue).

Who is this for?

Women diagnosed with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have received or are planning to receive a breast MRI. You may also enroll if you have not been diagnosed with breast cancer but are scheduled to receive an MRI to look at a suspicious mass (lump) in your breast. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Photoacoustic imaging of the breast, for about 30 minutes, once</li> </ul> You may choose to repeat this process up to 10 times (on separate days)
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Research shows that mammograms are more difficult to read in women with dense breasts.</li> <li class="seamTextUnorderedListItem">Photoacoustic imaging is a type of scan that uses sound and light to study breast tissue.</li> <li class="seamTextUnorderedListItem">Researchers are studying whether photoacoustic imaging makes it easier to see tumors in women with dense breasts.</li> <li class="seamTextUnorderedListItem">They are also studying if they can learn anything new about breast tissue and tumors with this experimental imaging technique.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03897270' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://en.wikipedia.org/wiki/Photoacoustic_imaging' target='_blank'>Wikipedia: Photoacoustic Imaging</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/types/breast/breast-changes/dense-breasts' target='_blank'>NCI Breast Cancer: Dense Breasts</a> </li><li class='seamTextUnorderedListItem'><a href='https://dmm.biologists.org/content/12/7/dmm039636' target='_blank'>Journal Article: Photoacoustic Imaging as a Tool to Probe the Tumour Microenvironment</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005545/' target='_blank'>Journal Article: Photoacoustic Imaging of Breast Cancer</a> </li></ul>

NEAREST SITE: 2314 miles
Wake Forest Baptist Health Sciences
Winston-Salem,NC

VISITS: 3 visits in 3 months

PHASE: NA

NCT ID: NCT05030038

Impact of Aromatase Inhibitors on Gut Bacteria in People with Stage 0-IV Breast Cancer

Oral Aromatase Inhibitors Modify the Gut Microbiome Effecting Estrogen Bioavailability Scientific Title

Purpose

To study the bacteria in your gut before and during treatment with an aromatase inhibitor.

Who is this for?

Women with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) hormone receptor positive (ER+ and/or PR+) breast cancer who are receiving an aromatase inhibitor, or women without breast cancer who are receiving an aromatase inhibitor to reduce their risk of breast cancer. You must not have received antibiotics within the last month. If you have HER2 positive (HER2+) breast cancer, you must not have received an antibody drug conjugate (ADC). Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood tests, 3 times within 3 months</li> <li class="seamTextUnorderedListItem">Stool samples, 3 times within 3 months</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The microbiome consists of the many bacteria, viruses, and fungi found in your digestive tract. Most of the microbiome consists of bacteria in your digestive system.</li> <li class="seamTextUnorderedListItem">These bacteria can be beneficial or harmful. The harmful bacteria cause disease, and the beneficial bacteria help keep you healthy.</li> <li class="seamTextUnorderedListItem">Aromatase inhibitors are a type of hormone therapy commonly used to treat hormone receptor-positive breast cancer. The approved aromatase inhibitors are anastrozole (Arimidex®), letrozole (Femara®), and exemestane (Aromasin®).</li> <li class="seamTextUnorderedListItem">You will collect fecal samples at home and either mail in the sample or drop it off at the lab.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05030038' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.hsph.harvard.edu/nutritionsource/microbiome/' target='_blank'>Harvard University: What is the Microbiome?</a> </li><li class='seamTextUnorderedListItem'><a href='https://breastcancernow.org/about-us/news-personal-stories/can-gut-bacteria-help-treat-breast-cancer' target='_blank'>Breast Cancer Now: Gut Bacteria and Breast Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy/aromatase-inhibitors' target='_blank'>Breastcancer.org: Aromatase Inhibitors</a> </li></ul>

NEAREST SITE: 2352 miles
University of Rochester
Rochester,NY

VISITS: 6 visits over 3-5 months

PHASE: NA

NCT ID: NCT03137095

Memory Problems During Chemotherapy in People with Stage I-III Breast Cancer

Longitudinal Pilot Mechanistic Study of the Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients and Non-Cancer Control Participants Scientific Title

Purpose

To study if and how your cognitive functioning skills, like memory and concentration, change as you receive chemotherapy.

Who is this for?

Women with newly diagnosed stage I, stage II, or stage III breast cancer who are planning to receive chemotherapy, and women who do not have breast cancer. Full eligibility criteria

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You will undergo the following over 3-5 months: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">6 cognitive tests, during chemotherapy and 1 month after chemotherapy</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cognitive tests study your cognition, which is your ability to think.</li> <li class="seamTextUnorderedListItem">Women without breast cancer will also be enrolled for comparison.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03137095' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/managing-cancer/side-effects/changes-in-mood-or-thinking/chemo-brain.html' target='_blank'>American Cancer Society: What is Chemo Brain?</a> </li></ul>

NEAREST SITE: 2383 miles
Mayo Clinic in Florida
Jacksonville,FL

VISITS: 1 visit

PHASE: NA

NCT ID: NCT06060561

Genetic Testing for Women Receiving a Biopsy

Genetic Testing to Improve Management of Patients Undergoing Breast Biopsy Scientific Title

Purpose

To use genetic testing results to improve personalized risk assessment for breast cancer.

Who is this for?

Women who are planning to receive a breast biopsy at Mayo Clinic Florida Breast Clinic. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saliva sample for genetic testing, in-person</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing looks for changes, sometimes called mutations or variants, in your DNA.</li> <li class="seamTextUnorderedListItem">Your genetic testing and biopsy results will be used to generate personalized risk assessment for breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06060561' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/breast-biopsy' target='_blank'>Breastcancer.org: Breast Biopsies</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/genomics/gtesting/genetic_testing.htm' target='_blank'>Centers for Disease Control and Prevention (CDC): What is Genetic Testing?</a> </li></ul>

NEAREST SITE: 2383 miles
Mayo Clinic in Florida
Jacksonville,FL

VISITS: At least 1 visit within 10 years

PHASE: NA

NCT ID: NCT05755269

Genetic Risk of Breast Cancer for African American and Hispanic Women

Genetic Risk Estimation in Breast Cancer and Assessing Health Disparities Scientific Title

Purpose

To study whether adding a genetic risk assessment to standard breast cancer risk assessment tools helps African American and Hispanic women make more informed decisions about breast cancer screening and prevention.

Who is this for?

African American/Black or Hispanic/Latinx women 30-75 years old with lobular carcinoma in situ (LCIS) or women at risk of breast cancer, including with a history of abnormal biopsy results. You must not have taken drugs to prevent breast cancer for longer than 6 months, received a mastectomy to reduce your risk of breast cancer, or have a breast cancer mutation such as BRCA1/2, PALB2, ATM, or CHEK2. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood sample for genetic/genomic testing</li> <li class="seamTextUnorderedListItem">Surveys, 2 times in 6 months, then every year for 10 years</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will receive your genetic testing results and your risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Traditional breast cancer risk assessments include family history, reproductive history, and breast density.</li> <li class="seamTextUnorderedListItem">This information can be combined with genetic information to provide a 10 year and lifetime risk for breast cancer.</li> <li class="seamTextUnorderedListItem">Including genetics with traditional screening techniques may help minority women make more informed decisions about screening and prevention strategies for breast cancer.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05755269' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/about-breast-cancer#section-breast-cancer-risk' target='_blank'>Breastcancer.org: Breast Cancer Risk</a> </li></ul>

NEAREST SITE: 2449 miles
Johns Hopkins Breast Imaging clinics
Baltimore,MD

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05181722

Personalized Support from a Patient Navigator After an Abnormal Mammogram

Evaluating the Use of Patient Navigation to Promote Timely Diagnostic Evaluation During the COVID-19 Pandemic Scientific Title

Purpose

To evaluate whether patient navigation can improve follow-up after an abnormal mammogram.

Who is this for?

Women who have had an abnormal mammogram at Johns Hopkins Breast Imaging Clinics and have not received follow-up testing. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized support from a patient navigator</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> Group 2: Control <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Patient navigators help people get the health care they need.</li> <li class="seamTextUnorderedListItem">In this study, a patient navigator will help you receive follow-up testing after an abnormal mammogram. This includes appointment reminder phone calls, health education, help with scheduling appointments, information about transportation options, assistance with language services, and help with insurance.</li> <li class="seamTextUnorderedListItem">Patient navigation may be an effective way to promote timely follow-up after an abnormal mammogram and may decrease the risk of a delayed breast cancer diagnosis.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05181722' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/community-resources/interventions/patient-navigation.htm' target='_blank'>Centers for Disease Control and Prevention: What is a Patient Navigator?</a> </li></ul>

NEAREST SITE: 2477 miles
Carolina Breast Imaging Specialists
Greenville,NC

VISITS: 3 visits within 2 years

PHASE: NA

NCT ID: NCT05625659

Imaging to Improve Breast Cancer Screening in Women With Dense Breasts

Comparison of Breast Cancer Screening With Dual-Energy Contrast-Enhanced Spectral Mammography to Digital Breast Tomosynthesis in Women With Dense Breasts (Contrast Mammography Imaging Screening Trial Scientific Title

Purpose

To study if dual-energy contrast-enhanced spectral mammography (CESM) can improve breast cancer screening in women with dense breasts.

Who is this for?

Women 45-74 years old with dense breasts. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard mammogram, 2 times within 1 year</li> <li class="seamTextUnorderedListItem">Contrast-enhanced spectral mammography (CESM), 2 times within 1 year</li> <li class="seamTextUnorderedListItem">Imaging contrast, by IV, 2 times within 1 year</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Email, text, or phone call</li> <li class="seamTextUnorderedListItem">Return to standard mammography for breast cancer screening</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Dual-energy contrast-enhanced spectral mammography (CESM) uses contrast to improve detection of breast cancer compared to standard mammograms.</li> <li class="seamTextUnorderedListItem">Some cancers, such as those present in dense breast tissue, may be visible on CESM but not on a standard mammogram.</li> <li class="seamTextUnorderedListItem">Breast cancer is harder to see on a mammogram of dense breasts.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05625659' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://densebreast-info.org/screening-technologies/contrast-enhanced-mammography/#:~:text=CEM%20can%20be%20used%20to,or%20abnormalities%20seen%20on%20mammograms.' target='_blank'>Dense Breast Info.org: Contrast-Enhanced Mammograms</a> </li><li class='seamTextUnorderedListItem'><a href='https://densebreast-info.org/for-patients/5-facts-you-should-know/' target='_blank'>Dense Breast Info.org: What to Know About Dense Breasts</a> </li></ul>

NEAREST SITE: 2496 miles
Dorothy G Hoefer Comprehensive Breast Center
Newport News,VA

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT03147430

Identifying Biomarkers for Early Detection of Breast Cancer

Early Detection of Breast Cancer in Women With Suspicious Mammograms Scientific Title

Purpose

To identify biomarkers in blood or saliva (spit) samples that detect early breast cancer.

Who is this for?

Women with suspicious mammogram results who are planning to receive a biopsy. You must have not been diagnosed with breast cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood sample</li> <li class="seamTextUnorderedListItem">Saliva (spit) sample</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A biomarker is a feature of a tumor, such as a protein or gene, that tells doctors more about the individual's tumor characteristics.</li> <li class="seamTextUnorderedListItem">Biomarkers for early stage breast cancer are needed, especially in people with dense breasts and/or small breast cancer tumors.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03147430' target='_blank'>ClinicalTrials.gov</a> </li></ul>

NEAREST SITE: 2517 miles
UPENN
Philadelphia,PA

VISITS: 1 visit

PHASE: NA

NCT ID: NCT04854304

Fast Breast MRI to Screen for Breast Cancer in Black Women with High Breast Density

Supplemental Screening for Breast Cancer With Abbreviated Breast MR for Black Women With Increased Breast Density Scientific Title

Purpose

To screen for breast cancer in black women with high breast density using Fast Breast MRI.

Who is this for?

Black women without breast cancer that have high breast density indicated by scores C (heterogeneously dense) and D (extremely dense) on the Breast Imaging Reporting and Data System (BI-RADS) scale. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Fast Breast MRI, 1 session</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Fast Breast MRI takes about 10 minutes to perform.</li> <li class="seamTextUnorderedListItem">Dense breasts make it harder for doctors to see breast cancers on mammograms.</li> <li class="seamTextUnorderedListItem">Women with dense breasts have a higher risk of developing breast cancer compared to women who don’t have dense breasts. </li> <li class="seamTextUnorderedListItem">For people with dense breasts, screening with Fast Breast MRI is sometimes recommended to detect breast cancer that might not be visible on a mammogram.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04854304' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/research-news/fast-mri-better-than-3d-mammo-for-dense-breasts#:~:text=Traditional%20breast%20MRI%20uses%20magnets,breast%20MRI%20is%20not%20perfect.' target='_blank'>Breastcancer.org: Fast Breast MRI</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/risk/factors/dense_breasts' target='_blank'>Breastcancer.org: Dense Breasts</a> </li></ul>

NEAREST SITE: 2561 miles
Memorial Sloan Kettering Bergen
Montvale,NJ

VISITS: 8 to 10 times for 2-3 years, then once a year for 2-3 years

PHASE: NA

NCT ID: NCT00823654

Measuring Hormone Levels to Study How Cancer Treatments & Inherited BRCA 1/2 Mutations Affect The Ovaries

Multi-Center Study of Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer and Lymphoma Scientific Title

Purpose

To study if a blood test that measures hormones can predict who will enter early menopause or develop fertility issues because of how chemotherapy and hormone therapy affect the ovaries; and to study the fertility and sexual health of women with inherited BRCA 1 or BRCA 2 mutations.

Who is this for?

Premenopausal women, 44 or younger, with DCIS or stage I, stage II, or stage III breast cancer planning to receive chemotherapy or tamoxifen. You may also enroll if you do not have breast cancer but have an inherited BRCA 1 or BRCA 2 mutation. Full eligibility criteria

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You will be assigned to 1 of 2 groups: Group 1: Women with DCIS or stage I-III breast cancer <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood draws, 8-10 times for 2-3 years, then once a year for 2-3 years (5 years total)</li> </ul> Group 2: Women with inherited BRCA mutations <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood draws, 5 times for the first year, then optional draws once a year for 4 years (5 years total)</li> </ul> Additional procedures <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer treatments can affect the ovaries, which may cause early menopause or difficulty becoming pregnant. </li> <li class="seamTextUnorderedListItem">Ovarian functioning can be assessed by evaluating the blood levels of certain hormones the ovaries produce.</li> <li class="seamTextUnorderedListItem">Inherited BRCA 1/2 mutations may affect your ovaries.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT00823654' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.youngsurvival.org' target='_blank'>Young Survival Coalition</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.facingourrisk.org/index.php' target='_blank'>FORCE: Facing Our Risk of Cancer Empowered</a> </li></ul>

NEAREST SITE: 2569 miles
Columbia University Irving Medical Center/NYP
New York,NY

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT05219695

Thermal Treatment for Stage I Breast Cancer and Benign Breast Tumors

Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI) Scientific Title

Purpose

To study the effects of harmonic motion imaging (HMI) and focused ultrasound (FUS) ablation before surgery (neoadjuvant).

Who is this for?

Women with a benign breast tumor or some stage I breast cancer who have not yet received surgery or radiation. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Harmonic motion imaging (HMI) scan, 2 times</li> <li class="seamTextUnorderedListItem">Focus ultrasound (FUS) ablation of tumor</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Harmonic motion imaging (HMI) is a type of scan that can look for changes in tissue before and after focused ultrasound (FUS) ablation.</li> <li class="seamTextUnorderedListItem">Focused ultrasound (FUS) ablation applies high-intensity focused ultrasound waves to a tumor, which ablates (heats) the tumor tissue to kill cancer cells.</li> <li class="seamTextUnorderedListItem">The main advantage of focused ultrasound (FUS) ablation is that it avoids surgery. Without surgery, recovery from the procedure is faster with less pain, and cosmetological results may be improved.</li> <li class="seamTextUnorderedListItem">Neoadjuvant therapy is when you receive treatment before surgery. Doctors use it to shrink tumors and to see how your cancer responds to the given therapies.</li> <li class="seamTextUnorderedListItem">The two most common types of benign breast lumps are cysts and fibroadenomas.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05219695' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ueil.bme.columbia.edu/research-projects/harmonic-motion-imaging' target='_blank'>Columbia University: Harmonic Motion Imaging</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/other/high-intensity-focused-ultrasound-hifu' target='_blank'>Cancer Research UK: High-Intensity Focused Ultrasound</a> </li></ul>

NEAREST SITE: 2574 miles
Montefiore Medical Center
Bronx,NY

VISITS: 1 visit

PHASE: NA

NCT ID: NCT03694756

Experimental Breast MRI Scan for People with Suspected Breast Cancer or Stage I-III Breast Cancer

TMEM-MRI: A Pilot Feasibility Study of Magnetic Resonance Imaging for Imaging of TMEM (Tumor Microenvironment of Metastasis) in Patients With Operable Breast Cancer Scientific Title

Purpose

To study the ability of TMEM-MRI, an experimental type of MRI scan, to detect breast cancer cells.

Who is this for?

People with a breast mass that is suspected to be breast cancer, or people with stage I, stage II, or some stage III breast cancer who have not yet received treatment. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">TMEM-MRI scan, 1 time</li> <li class="seamTextUnorderedListItem">Contrast agent, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Biopsy (if you have not yet received one)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy rather than x-ray energy.</li> <li class="seamTextUnorderedListItem">Tumor Microenvironment of Metastasis - Magnetic Resonance Imaging (TMEM-MRI) scans are an experimental type of MRI scan that can detect tumor areas that are more likely to travel to other sites in the body.</li> <li class="seamTextUnorderedListItem">TMEM-MRI scans may be useful to identify tumors with a higher chance of coming back (recurrence) after treatment.</li> <li class="seamTextUnorderedListItem">TMEM-MRI scans may also be useful for studying the response to neoadjuvant (before surgery) treatment such as chemotherapy and hormone therapy.</li> <li class="seamTextUnorderedListItem">A contrast agent, also called a tracer, is a radioactive substance that can look for and attach to cancer cells.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03694756' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/breast-mri' target='_blank'>Breastcancer.org: Breast MRI</a> </li></ul>

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT04996316

MammoScreen Questionnaire to Determine Breast Cancer Risk and Make Screening Decisions

Implementing USPSTF Recommendations for Breast Cancer Screening and Prevention by Integrating Clinical Decision Support Tools With the Electronic Health Record Scientific Title

Purpose

To collect information to use MammoScreen for breast cancer screening.

Who is this for?

Women 40-74 years old who have not had breast or ovarian cancer. Full eligibility criteria

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You will receive the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Interview, 1 time</li> <li class="seamTextUnorderedListItem">MammoScreen questionnaire, 1 time</li> </ul> followed by: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Interviews, 3 times within 3 years (optional)</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MammoScreen is a questionnaire that helps identify breast cancer risk and make screening decisions.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04996316' target='_blank'>ClinicalTrials.gov</a> </li></ul>

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT05838417

Survey to Understand Breast Cancer Screening Knowledge and Attitudes

Promoting Informed Choice for Breast Cancer Screening: A Longitudinal Study Scientific Title

Purpose

To study attitudes and knowledge about breast cancer screening and to determine if conversations with primary care doctors increase breast cancer screening.

Who is this for?

Women 39-49 years old who have not been diagnosed with breast cancer and do not have a known BCRA1/2 gene mutation. Full eligibility criteria

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You will complete the following: <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Surveys, by email or phone, 4 times within 1 year</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Conversations between primary care doctors and healthy women may affect women's attitudes and understanding of breast cancer screening and therefore may increase screening.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05838417' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/mammograms/recommendations' target='_blank'>Breastcancer.org: Mammogram Screening Guidelines</a> </li></ul>

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT05677048

Increasing Genetic Testing Among Families at Risk for Breast Cancer

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention Scientific Title

Purpose

To increase the rate of genetic testing among family members with mutations that are associated with hereditary breast cancer.

Who is this for?

People with a BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM mutation and their mother, father, child, or full sibling with a BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM mutation. Full eligibility criteria

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You will be randomly assigned to 1 of 4 groups: Group 1: Standard of Care <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Letter about hereditary cancer and genetic testing</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> Group 2: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Access to free genetic testing and counseling</li> <li class="seamTextUnorderedListItem">Letter about hereditary cancer and genetic testing</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> Group 3: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online educational materials</li> <li class="seamTextUnorderedListItem">Assistance from a family genetic navigator</li> <li class="seamTextUnorderedListItem">Letter about hereditary cancer and genetic testing</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> Group 4: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online educational materials</li> <li class="seamTextUnorderedListItem">Assistance from a family genetic navigator</li> <li class="seamTextUnorderedListItem">Access to free genetic counseling and testing</li> <li class="seamTextUnorderedListItem">Letter about hereditary cancer and genetic testing</li> <li class="seamTextUnorderedListItem">Surveys</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing looks for changes, sometimes called mutations or variants, in your DNA.</li> <li class="seamTextUnorderedListItem">Mutations in genes such as BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM can lead to breast cancer.</li> <li class="seamTextUnorderedListItem">These mutations are hereditary, meaning they are passed down from parent to child.</li> <li class="seamTextUnorderedListItem">If you have a family member with one of these mutations, genetic testing is important so you can understand your risk and receive appropriate screening for breast cancer.</li> <li class="seamTextUnorderedListItem">Your family member will also participate in this trial.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05677048' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing/brca' target='_blank'>Breastcancer.org: BRCA Mutations and Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.facingourrisk.org/portal/inherited-cancer-risk' target='_blank'>FORCE: What is Genetic Testing?</a> </li></ul>

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT05483283

Empowerment and Navigation Sessions for Latina Women Ages 30+ with Breast Cancer or a Family History of Breast/Ovarian Cancer

Empowering Vulnerable and Resilient Latinas to Obtain Breast Cancer Care Scientific Title

Purpose

To compare the impact of empowerment and navigation sessions with standard of care sessions on whether Latina women decide to receive genetic testing and/or genetic counseling.

Who is this for?

Latina women ages 30+ with stage I, stage II, stage III, or stage IV (metastatic) breast cancer or with a family history of breast or ovarian cancer. You must have one social determinant of health risk factor, such as: perceived financial struggles, transportation difficulties, exposure to violence, housing challenges, social isolation/challenges. You must not have received genetic testing or genetic counseling. Full eligibility criteria

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You will be randomly assigned to 1 of 2 groups: Group 1: Experimental <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li> </ul> Group 2: Standard of Care <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, breast cancer screening, and diet and physical activity for breast cancer prevention.</li> <li class="seamTextUnorderedListItem">Standard of care sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, how to share breast cancer information, and testimonials and include role playing activities and group discussions.</li> <li class="seamTextUnorderedListItem">You can receive up to $100 for participation.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05483283' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/cancer-prevention-and-early-detection-facts-and-figures/making-the-case-for-health-equity.pdf' target='_blank'>American Cancer Society: Health Equity and Social Determinants of Health</a> </li><li class='seamTextUnorderedListItem'><a href='https://health.gov/healthypeople/priority-areas/social-determinants-health' target='_blank'>US Department of Health and Human Services: Social Determinants of Health</a> </li></ul>

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT05853848

Mail and Phone Based Methods to Remind Women to Receive Mammograms

Randomized Comparison of Mail- and Phone-based Interventions Promoting Mammogram Screening Scientific Title

Purpose

To compare 4 methods of encouraging women to schedule mammograms.

Who is this for?

Women 52-74 years old who have Geisinger Health Plan insurance who have not had a mammogram since October 2021. You must have not had a bilateral mastectomy. Full eligibility criteria

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You will be randomly assigned to 1 of 4 groups: Group 1 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Postcard with phone number to call for help scheduling a mammogram</li> </ul> Group 2 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Letter with phone number to call for help scheduling a mammogram</li> </ul> Group 3 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Automated call with option to press button for help scheduling a mammogram</li> </ul> Group 4 <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Live call offering help scheduling a mammogram</li></ul>
<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A mammogram is a breast cancer screening procedure involving taking an x-ray picture of the breast.</li></ul>
<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05853848' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/mammograms.htm' target='_blank'>Centers for Disease Control and Prevention: What Is a Mammogram?</a> </li></ul>