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Find Breast Cancer Clinical Trials That Are Right For You
The clinical trials listed below are open in the U.S. for people with DCIS (stage 0), stage 1, stage 2, stage 3, or stage 4 (metastatic)
breast cancer. Clinical trials are available for people who are newly diagnosed with breast cancer, currently in treatment, experiencing
breast cancer recurrence, living with metastatic disease, as well as breast cancer survivors who have completed treatment.
Use the search box and filters to find a trial that’s right for you.
Currently viewing trials
(Last updated: January 16, 2026)
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Treatment
Brain Mets
BRCA1/2 (inherited)
Chemotherapy
Hormone Therapy
Leptomeningeal Disease
Radiation Oncology
Surgery
Surgery: Reconstruction
Targeted Therapy: All
Targeted Therapy: ADC
Targeted Therapy: Anti-HER2 Therapy
Targeted Therapy: CDK Inhibitors
Targeted Therapy: PARP Inhibitors
Targeted Therapy: Tumor Mutations
Targeted Therapy: Other Targeted Therapy
Vaccines and Immunotherapy
Other Treatment
Non-Treatment
Activities
Complementary and Integrative Medicine
Decision Support
Diagnosing Breast Cancer
Genetics/Family History
Having Children
Healthy/High Risk
Imaging
Lymphedema
Managing Side Effects
No Travel Required
Predicting Response to Treatment
Preventing Breast Cancer
Preventing Recurrence
Support/Education
Surveys/Interviews/Registries
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AKT
ALK
AR
BARD1
BRCA1/2 (tumor)
BRIP1
CD205
CD70
CHEK2 or CHEK1
dMMR/MSI-H
ESR1
FGFR
HER2/ERBB2
HLA
MET or C-Met
NTRK
PALB2
PIK3CA or PI3K
PTEN
RAD51
RAF (including BRAF)
RAS (KRAS or NRAS)
RB
ROS1
TP53
Click here to view online studies and trials that do not require site visits
1
NEAREST SITE: 3 miles
University of California San Francisco
San Francisco,CA
VISITS: Online surveys
PHASE: NA
NCT ID: NCT02620852
WISDOM Study: Women Informed to Screen Depending on Measures of Risk
Enabling a Paradigm Shift: A Preference-Tolerant RCT of Personalized vs. Annual Screening for Breast Cancer Scientific Title
Purpose
To learn if risk-based breast screening is as safe and effective as annual mammogram screening for reducing risk and detecting breast cancer.
Who is this for?
Women between the ages of 40 and 70 who have never been diagnosed with breast cancer or ductal carcinoma in situ (DCIS).
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups, or you can choose your study group. </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Personalized, Risk-Based Screening</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening recommendations based on comprehensive, personal risk assessment</li> <li class="seamTextUnorderedListItem">Saliva sample genetic test</li> <li class="seamTextUnorderedListItem">Online, annual health questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard Annual Screening</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening recommendation for annual mammograms</li> <li class="seamTextUnorderedListItem">Online, annual health questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized risk-based screening will take multiple risk factors into consideration, including genetic markers, to determine how often you should have a mammogram.</li> <li class="seamTextUnorderedListItem">This study will help researchers learn if risk-based screening, which helps women learn more about their personal breast cancer risk, is less stressful and as successful at detecting breast cancer as annual screening. </li> <li class="seamTextUnorderedListItem">This study is available in English and Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02620852' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.thewisdomstudy.org/' target='_blank'>WISDOM: Study Information Page</a> </li></ul>
2
NEAREST SITE: 22 miles
Contra Costa Regional Medical Center
Martinez,CA
VISITS: 2 visits in 1 year
PHASE: NA
NCT ID: NCT05334069
Collecting Blood Samples From People With and Without Breast Cancer to Evaluate Tests for Early Cancer Detection
Blinded Reference Set for Multicancer Early Detection Blood Tests Scientific Title
Purpose
To collect blood and tissue samples from people with breast cancer and people without breast cancer to evaluate tests for early cancer detection.
Who is this for?
People 40-75 years old with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have not yet received treatment, or who do not have breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide blood samples, 2 times</li> <li class="seamTextUnorderedListItem">Provide tissue samples (for people with cancer), 2 times</li> <li class="seamTextUnorderedListItem">Complete questionnaires, 2 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Collecting and storing samples of blood and tissue from patients with and without breast cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05334069' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis' target='_blank'>National Cancer Institute: How Cancer Is Diagnosed</a> </li></ul>
3
NEAREST SITE: 27 miles
Stanford University School of Medicine
Stanford,CA
VISITS: 1 visit
PHASE: NA
NCT ID: NCT01034033
A Study of How Cancer Develops in Women With BRCA1/2 or Other Genetic Mutations
Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples Scientific Title
Purpose
To analyze blood samples from women at high risk of developing breast cancer in order to learn more about how cells change over time from normal to cancerous.
Who is this for?
Women at high-risk for developing breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> All participants will provide blood samples.</p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">BRCA1 and BRCA2 are tumor suppressor genes.</li> <li class="seamTextUnorderedListItem">Inheriting a mutation in the BRCA1 or BRCA2 gene increases cancer risk. </li> <li class="seamTextUnorderedListItem">For the cancer to develop, though, the cells will need to first acquire other mutations.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT01034033' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://stanfordhealthcare.org/medical-conditions/cancer/hboc/brca-1-and-2.html' target='_blank'>Stanford: About Hereditary Breast Ovarian Cancer Syndrome</a> </li><li class='seamTextUnorderedListItem'><a href='https://clinicaltrials.gov/ct2/show/NCT01034033?term=NCT01034033&rank=1' target='_blank'>ClinicalTrials.gov trial info</a> </li></ul>
4
NEAREST SITE: 28 miles
Kaiser Permanente-Division of Research
Pleasanton,CA
VISITS: 2 times within 1 year
PHASE: NA
NCT ID: NCT06995898
Multi-Cancer Detection Blood Test to Screen for Cancer for Healthy People and People with Stage 0 Breast Cancer
The Vanguard Study: Testing a New Way to Screen for Cancer Scientific Title
Purpose
To study how multi-cancer detection (MCD) tests may work as cancer screening tools.
Who is this for?
People, aged 45-75 years, without cancer. People with stage 0 (DCIS) breast cancer may enroll.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MCD blood test</li> <li class="seamTextUnorderedListItem">Review of your medical records</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood test</li> <li class="seamTextUnorderedListItem">Review of your medical records</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A multi-cancer detection (MCD) test measures markers in the blood to screen for multiple cancers at the same time. MCDs may work as cancer screening tools.</li> <li class="seamTextUnorderedListItem">This study will assess how well MCD tests perform as cancer screening tools. It will also help researchers understand how patients and their doctors make decisions about their care when the MCD test result comes back normal or abnormal.</li> <li class="seamTextUnorderedListItem">You will be notified of any abnormal test results.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06995898' target='_blank'>ClinicalTrials.gov</a> </li></ul>
5
NEAREST SITE: 336 miles
University of California at Los Angeles
Los Angeles,CA
VISITS: 1 visit
PHASE: NA
NCT ID: NCT04297020
Studying the Effects of Anti-Estrogen Therapy on the Brain of Women with Stage I-III Breast Cancer
Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine Therapy Scientific Title
Purpose
To see if anti-estrogen therapy affects brain health.
Who is this for?
Women between the ages of 35 and 65 with stage I, stage II, or stage III breast cancer who are taking hormone therapy after surgery. This trial is also enrolling women who have never been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">1 Brain fMRI (functional MRI)</li> <li class="seamTextUnorderedListItem">Cognitive testing</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial will use an advanced brain MRI technique called functional MRI (fMRI).</li> <li class="seamTextUnorderedListItem">fMRI measures changes in blood flow that happen during mental activity. </li> <li class="seamTextUnorderedListItem">Research suggests that the cognitive issues experienced by some women who receive treatment for breast cancer--also called <q>chemo brain</q>--may actually be caused by anti-estrogen therapy and not chemotherapy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04297020' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.medscape.com/viewarticle/932091' target='_blank'>MedScape: In Breast Cancer, Is Chemobrain Really Endocrine Brain?</a> </li><li class='seamTextUnorderedListItem'><a href='https://en.wikipedia.org/wiki/Functional_magnetic_resonance_imaging' target='_blank'>Wikipedia: Functional MRI</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.radiologyinfo.org/en/info.cfm?pg=fmribrain' target='_blank'>RadiologyInfo.org: fMRI</a> </li></ul>
6
NEAREST SITE: 336 miles
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles,CA
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05978128
Increasing Breast Cancer Screening Using Advocates and Supporters
Utilizing Spheres of Influence to Increase Cancer Screening: Empowering Community Health Advocates Scientific Title
Purpose
To investigate why some people may receive breast cancer screening but not lung cancer screening and to determine if advocates and supporters can increase screening.
Who is this for?
People at least 40 years old who do not currently have cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Access to online educational materials, 3 times within 2 years</li> <li class="seamTextUnorderedListItem">Meet with a patient navigator</li> <li class="seamTextUnorderedListItem">Education materials to share with friends/family on benefits of breast cancer screening</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer screening with mammography is widely accepted and commonly used.</li> <li class="seamTextUnorderedListItem">Advocates and supporters of lung cancer screening may increase the willingness to receive this screening.</li> <li class="seamTextUnorderedListItem">This trial also includes lung cancer screening.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05978128' target='_blank'>ClinicalTrials.gov</a> </li></ul>
7
NEAREST SITE: 336 miles
UCLA Kaiser Permanente Center for Health Equity
Los Angeles,CA
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05298605
Faith in Action: Church-Based Education and Navigation to Increase Breast Cancer Screening in Korean Women
Faith in Action! A Cluster-Randomized Trial to Evaluate the Efficacy of a Church-based Navigation Model to Increase Breast Cancer Screening Among Korean Women in Los Angeles Scientific Title
Purpose
To study if the Faith in Action cancer screening education and navigation curriculum increases breast cancer screening among Korean American women.
Who is this for?
Korean women at least 45 years old who do not have breast cancer, have not received a screening mammogram in the last 2 years, and are members of participating Korean churches in Los Angeles, California.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Faith in Action cancer screening education and navigation curriculum</li> <li class="seamTextUnorderedListItem">American Cancer Society Screening Guidelines pamphlet</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Presentation on physical activity and nutrition</li> <li class="seamTextUnorderedListItem">American Cancer Society Screening Guidelines pamphlet</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Faith in Action is a curriculum designed to deliver cancer education and increase motivation to participate in breast cancer screening through proven approaches such as one-on-one education, small media, and workshops.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05298605' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ucla.clinicaltrials.researcherprofiles.org/trial/NCT05298605' target='_blank'>UCLA: Faith in Action</a> </li></ul>
8
NEAREST SITE: 343 miles
Keck Medicine of USC Koreatown
Los Angeles,CA
VISITS: 1 visit
PHASE: NA
NCT ID: NCT06336928
Comparing Liquid Biopsy Results to Mammogram and Biopsy Results
A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis Scientific Title
Purpose
To compare liquid biopsy results to mammogram and biopsy results.
Who is this for?
Women who have not been diagnosed with breast cancer and women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer who have not started treatment or have completed treatment.
Full eligibility criteria
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Liquid biopsy blood test</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A liquid biopsy is a blood test that can detect cancer cells.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06336928' target='_blank'>ClinicalTrials.gov</a> </li></ul>
9
NEAREST SITE: 348 miles
Los Angeles County-USC Medical Center
Los Angeles,CA
VISITS: 1 visit
PHASE: I
NCT ID: NCT06171607
Contrast-Enhanced Ultrasound to Identify Breast Masses
Characterizing Breast Masses Using an Integrative Framework of Machine Learning and Radiomics Scientific Title
Purpose
To learn if using contrast-enhanced ultrasound (CEUS) will help to determine if an ultrasound-guided biopsy is necessary.
Who is this for?
Women who are planning to receive an ultrasound-guided biopsy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast-enhanced ultrasound (CEUS) scan with Lumason or DEFINITY contrast agent, by IV, 1 time</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasounds use sound waves to produce images of structures within your body without using radiation. Ultrasounds are widely used to diagnose many diseases in the body.</li> <li class="seamTextUnorderedListItem">A contrast-enhanced ultrasound (CEUS) is an ultrasound given with a contrast agent that helps improve images obtained from the scan.</li> <li class="seamTextUnorderedListItem">In this trial, Lumason and Perflutren are the contrast agents.</li> <li class="seamTextUnorderedListItem">The scan will take 1-1.5 hours.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06171607' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/breast-biopsy' target='_blank'>Breastcancer.org: Breast Biopsies</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/drugs-supplements/perflutren-lipid-microsphere-intravenous-route/side-effects/drg-20067608?p=1' target='_blank'>Mayo Clinic: Perflutren Ultrasound Contrast Agent</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/drugs-supplements/sulfur-hexafluoride-lipid-type-a-microspheres-injection-route-intravenous-route/side-effects/drg-20405988?p=1' target='_blank'>Mayo Clinic: Lumason Ultrasound Contrast Agent</a> </li></ul>
10
NEAREST SITE: 353 miles
City of Hope
Duarte,CA
VISITS: 10 visits within 3 years
PHASE: NA
NCT ID: NCT05366881
Blood Test to Detect Cancer After Treatment for Stage I-III Breast Cancer
cfDNA Assay Multicenter Prospective Observational Validation for Early Cancer Detection, Minimal Residual Disease, and Relapse (CAMPERR) Scientific Title
Purpose
To evaluate the ability of a blood test to detect whether someone's cancer is gone after completing treatment or if it has returned before it can be detected with standard methods.
Who is this for?
People at least 40 years old with stage I, stage II, or stage III breast cancer who were diagnosed within the last 3 months or whose cancer came back within the last 5 years, and people who do not have breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood samples, 10 times within 3 years</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">When cancer cells die, they release DNA into the bloodstream. This DNA can be detected following a blood test. This is sometimes called a liquid biopsy.</li> <li class="seamTextUnorderedListItem">This trial is testing what detection or no detection of cancer cell DNA (cfDNA) means for the patient.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling healthy people and people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05366881' target='_blank'>ClinicalTrials.gov</a> </li></ul>
11
NEAREST SITE: 446 miles
CureScience Institute
San Diego,CA
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05106725
Registry of Wearable Device Data to Study Brain Metastasis
Study of Clinical Biomarkers in Human Health and Disease (Healthiomics) Scientific Title
Purpose
To collect wearable device data and biological samples to study brain metastasis and develop new ways to treat brain metastasis.
Who is this for?
People with metastatic (stage IV) breast cancer that has spread to the brain (brain metastases) and people that do not have cancer or a brain disorder.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Wearable device</li> <li class="seamTextUnorderedListItem">Collection of biological samples: blood, tumor, cerebrospinal fluid, urine</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Wearable devices such as FitBits are used to track your physical activity.</li> <li class="seamTextUnorderedListItem">Cerebrospinal fluid (CSF) is the fluid that surrounds your brain and spinal cord. CSF is typically collected during a procedure called a lumbar puncture, also known as a spinal tap.</li> <li class="seamTextUnorderedListItem">If you do not have cancer or a brain disorder, your data will be compared to data collected by people with brain metastasis.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05106725' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://mbcbrainmets.org/' target='_blank'>MBCBrainMets.org</a> </li></ul>
12
NEAREST SITE: 602 miles
University of Utah Health Hospitals/Huntsman Cancer Institute Population Sciences
Salt Lake City,UT
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06305312
Referral for Assistance with Basic Needs After an Abnormal Mammogram
Community Services Navigation to Advance Health Equity in Breast Cancer Screening (B-SINCERE) Scientific Title
Purpose
To study if connecting people to assistance with food, housing, utilities, and transportation increases follow-up after an abnormal mammogram result.
Who is this for?
People with an abnormal result after a mammogram who have not been diagnosed with breast cancer and need support with food, housing, utilities, and/or transportation. You must live in or near Salt Lake City, Utah.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Referral to United Way of Salt Lake's community referral services (SINCERE)</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard referral to community resources</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Women with greater need for food, housing, utilities, and transportation are about half as likely to follow up after an abnormal mammogram than women without such needs.</li> <li class="seamTextUnorderedListItem">This trial is studying the United Way of Salt Lake's community referral services (SINCERE) intervention, which connects people to assistance with these needs.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06305312' target='_blank'>ClinicalTrials.gov</a> </li></ul>
13
NEAREST SITE: 660 miles
Mayo Clinic in Arizona
Scottsdale,AZ
VISITS: 1 visit
PHASE: NA
NCT ID: NCT06036875
Survey to Understand How Black and Hispanic Women Perceive Their Risk for Breast Cancer
CARE: Cancer Risk Perception and Women of Color Scientific Title
Purpose
To study how Black and Hispanic women understand their current and lifetime risk for breast cancer.
Who is this for?
Women, age 25-50 years, who are Black and/or Hispanic and who live in Arizona or Florida with no history of breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Survey, 1 time</li> <li class="seamTextUnorderedListItem">Interview (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is examining the relationship between risk factors for breast cancer and a person's perceptions of those risk factors and if these relationships are different according to race and ethnicity.</li> <li class="seamTextUnorderedListItem">This study is also exploring how people reduce their risk for breast cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06036875' target='_blank'>ClinicalTrials.gov</a> </li></ul>
14
NEAREST SITE: 714 miles
Navajo Nation Center for Indigenous Health
Chinle,AZ
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06957535
Virtual Program to Increase Mammography for Native American Women
Community-led Navigation to Address Disparities in Mammography Among Native American Women Scientific Title
Purpose
To increase breast cancer screening with mammography with a program called TEAM.
Who is this for?
American Indian or Alaska Native women, age 40-74 years, who receive care at Chinle Comprehensive HealthCare Facility (Arizona). You must not have a history of breast cancer, and you must not have received a mammogram in the last year.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">TEAM, virtual</li> <li class="seamTextUnorderedListItem">Individual navigation support from a Diné peer-navigator</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">TEAM, virtual</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Tablet-based Education to improve the Acceptance of Mammography (TEAM) is a culturally tailored mammography education program.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06957535' target='_blank'>ClinicalTrials.gov</a> </li></ul>
15
NEAREST SITE: 752 miles
University of Arizona
Tucson,AZ
VISITS: 1 visit
PHASE: NA
NCT ID: NCT03954431
Breast Computed Tomography (CT) Scan for Healthy or High-Risk Women
Study of High-resolution, Lower Dose Dedicated Breast CT. Scientific Title
Purpose
To study if a new type of breast scan called dedicated breast CT or BCT can see small structures in the breast clearly and diagnose breast cancer more accurately.
Who is this for?
Women, age 40 years and older, who are planning to receive a breast scan or a breast biopsy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast CT scan</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The breast CT device will take multiple pictures of the person's breast and create a 3D image of the breast. It does not compress or squash the breast like a mammogram.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03954431' target='_blank'>ClinicalTrials.gov</a> </li></ul>
16
NEAREST SITE: 804 miles
Bozeman Health Deaconess Hospital
Bozeman,MT
VISITS: Coincides with routine care, at least 1 visit every year
PHASE: NA
NCT ID: NCT02012699
Registry to Study Cancer Prevention, Detection, and Treatment
Integrated Cancer Repository for Cancer Research Scientific Title
Purpose
To create a registry to study strategies for prevention, screening, early detection, and personalized treatment of cancer.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer, people at high risk for breast cancer, or people who have not been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will be asked to provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide blood and urine samples during routine visits</li> <li class="seamTextUnorderedListItem">Provide tissue samples from surgery or biopsy</li> <li class="seamTextUnorderedListItem">Questionnaires, 1 time every year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This registry will compare samples between people with breast cancer, people at high risk for breast cancer, and people who do not have breast cancer.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02012699' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://icare2project.org' target='_blank'>iCaRe2 Project</a> </li></ul>
17
NEAREST SITE: 941 miles
University of Colorado Denver
Aurora,CO
VISITS: 2 visits in 1 year
PHASE: II
NCT ID: NCT06441474
Study of How Women Understand Breast Cancer Risk and Make Screening Decisions
Understanding and Addressing Rejection of Personalized Cancer Risk Information Scientific Title
Purpose
To study how women understand their breast cancer risk and make breast cancer screening decisions.
Who is this for?
Women 39-49 years old who have not been diagnosed with breast cancer and do not have a BRCA1/2 mutation. You must be receiving care at UCHealth in Denver, Colorado or Washington University in St. Louis, Missouri.
Full eligibility criteria
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast Cancer Risk Assessment Tool (BCRAT)</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times in 1 year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Breast Cancer Risk Assessment Tool (BCRAT) will be used to identify your breast cancer risk using the following factors: 1) age, 2) age at first menstrual period, 3) age at first live birth, 4) first-degree relatives with breast cancer, 5) history of abnormal breast biopsy, and 6) race/ethnicity.</li> <li class="seamTextUnorderedListItem">This study will study why women may think their breast cancer risk is lower than it really is (risk rejection).</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06441474' target='_blank'>ClinicalTrials.gov</a> </li></ul>
18
NEAREST SITE: 1251 miles
Hays Medical Center Dreiling-Schmidt Cancer Institute
Hays,KS
VISITS: 1 visit
PHASE: NA
NCT ID: NCT02302742
A Registry for People with Triple Negative or ER Low, HER2- Breast Cancer or an Inherited BRCA1/2 or Certain Other Mutations
PROspective Evaluation of GErmline Mutations, Cancer Outcome and Tissue Biomarkers: A Registry for Patients With Triple Negative Breast Cancer and Germline Mutations (PROGECT) Scientific Title
Purpose
To learn more about the relationship between genetic mutations and cancer outcomes.
Who is this for?
People with inherited BRCA1/2 mutations or certain other genetic mutations (see list below) and people with stage I, stage II, stage III, or stage IV triple negative (ER-, PR-, HER2-) or ER Low (1%-10% ER) breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> This is a data collection (registry) study. You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">1 blood test</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer that tests positive for 1%-10% estrogen receptors is called ER Low.</li> <li class="seamTextUnorderedListItem">This trial is enrolling people with triple negative as well as ER Low breast cancer.</li> <li class="seamTextUnorderedListItem">Studies have found a relationship between triple negative breast cancer and inherited BRCA1 and BRCA2 mutations. </li> <li class="seamTextUnorderedListItem">Targets or mutations: BRCA1, BRCA2, PTEN, P53, and PALB2</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02302742' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.cancer.net/cancer-types/hereditary-breast-and-ovarian-cancer' target='_blank'>ASCO: Hereditary Breast and Ovarian Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='http://ww5.komen.org/BreastCancer/InheritedGeneticMutations.html' target='_blank'>Susan G. Komen: Inherited Gene Expressions</a> </li><li class='seamTextUnorderedListItem'><a href='https://tnbcfoundation.org' target='_blank'>Triple Negative Breast Cancer Foundation</a> </li><li class='seamTextUnorderedListItem'><a href='https://ghr.nlm.nih.gov/condition/breast-cancer' target='_blank'>NIH Genetics Home Reference: Breast Cancer</a> </li></ul>
19
NEAREST SITE: 1331 miles
Hendrick Health - Vera West Women's Center
Abilene,TX
VISITS: 1 visit
PHASE: NA
NCT ID: NCT06643767
Bexa Breast Exam for Breast Cancer Screening
Evaluation of the Bexa Breast Examination (BBE) As an Effective Solution to Breast Cancer Early Detection Scientific Title
Purpose
To compare the Bexa™ Breast Exam to the standard of care (mammogram) for detecting masses and breast cancer.
Who is this for?
Women 30-75 years old who are planning to receive a mammogram.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following, together called the Bexa™ Breast Exam: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Scan with the Bexa™ device</li> <li class="seamTextUnorderedListItem">Ultrasound scan</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Bexa™ device uses highly accurate pressure sensors to study breast tissue. It is low cost, portable, and does not use radiation.</li> <li class="seamTextUnorderedListItem">Bexa™ may be better for identifying breast masses than a standard of care mammogram.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06643767' target='_blank'>ClinicalTrials.gov</a> </li></ul>
20
NEAREST SITE: 1615 miles
Mayo Clinic in Rochester
Rochester,MN
VISITS: Up to 5 visits in 1 year
PHASE: NA
NCT ID: NCT04799535
Ultrasound Scans to Diagnose Breast Cancer and Monitor Response to Treatment for Stage I-III Breast Cancer
Quantitative Microvasculature Imaging for Breast Cancer Detection and Monitoring Scientific Title
Purpose
To study how well breast ultrasound scans can diagnose breast cancer and measure response to treatment.
Who is this for?
People who are planning to receive or have received a breast biopsy, and people with stage I, stage II, or some stage III breast cancer who are planning to receive chemotherapy and/or hormone therapy before surgery (neoadjuvant).
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast ultrasound scan, up to 5 times in 1 year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasounds use sound waves to produce images of structures within your body.</li> <li class="seamTextUnorderedListItem">Diagnostic procedures, such as breast ultrasound, may help find and diagnose breast cancer and may help measure response to earlier treatment.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04799535' target='_blank'>ClinicalTrials.gov</a> </li></ul>
21
NEAREST SITE: 1615 miles
Mayo Clinic in Rochester
Rochester,MN
VISITS: 1-2 visits within 6 months
PHASE: NA
NCT ID: NCT06058650
Molecular Breast Imaging to Guide Biopsy
Pilot Clinical Study to Evaluate Molecular Breast Imaging- Guidance for Sampling of Breast Abnormalities Scientific Title
Purpose
To study how well molecular breast imaging (MBI) helps guide the collection of cells during a breast biopsy.
Who is this for?
Women who previously received breast imaging with mammography, ultrasound, MRI, or molecular breast imaging (MBI).
Full eligibility criteria
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<p class="seamTextPara"> You will be assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Biopsy Not Recommended or Previous Imaging/Biopsy Showed Benign (Normal) Results</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI), 1 time</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Biopsy Recommended</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI), 1 time</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast biopsy</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Collection of abnormal cells during a biopsy is often guided by either ultrasound or mammography in order to ensure that a sample of the correct part of the breast is taken.</li> <li class="seamTextUnorderedListItem">Sometimes abnormal tissue cannot be seen on ultrasound or mammography, and therefore, a biopsy guided with ultrasound or mammography may not always be accurate.</li> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI) is a method for detecting abnormal cells on a scan that uses injection of a radioactive tracer. Breast cancer cells take up this tracer more than normal cells, and this allows doctors to see the cancer cells on a scan.</li> <li class="seamTextUnorderedListItem">Technetium Tc-99m sestamibi is the tracer used in this study.</li> <li class="seamTextUnorderedListItem">MBI may improve the detection of some breast tumors.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06058650' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/molecular-breast-imaging' target='_blank'>Breastcancer.org: Molecular Breast Imaging</a> </li></ul>
22
NEAREST SITE: 1615 miles
Mayo Clinic in Rochester
Rochester,MN
VISITS: 1 visit
PHASE: NA
NCT ID: NCT04692818
Ultrasound Scan to Diagnose Breast Masses Before Biopsy
3D Multimodal Ultrasound Imaging for Breast Cancer Scientific Title
Purpose
To study how well a new ultrasound imaging method works to diagnose breast masses.
Who is this for?
Women with a breast mass who are planning to receive a biopsy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasound scan</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasounds use sound waves to produce images of structures within your body.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04692818' target='_blank'>ClinicalTrials.gov</a> </li></ul>
23
NEAREST SITE: 1615 miles
Mayo Clinic in Rochester
Rochester,MN
VISITS: 1 visit
PHASE: NA
NCT ID: NCT07207564
Blood Sample Collection to Better Predict Breast Cancer Risk for Healthy Women
Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk Scientific Title
Purpose
To study genetic and other factors to learn how non-cancerous breast diseases might lead to breast cancer.
Who is this for?
Women who had a breast biopsy at Mayo Clinic between 2002-2022 that was not cancer. You must not have been diagnosed with breast cancer within 6 months of this biopsy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide blood or saliva (spit) sample</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Features in the blood and breast tissue from people with non-cancerous breast disease may help predict breast cancer risk.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07207564' target='_blank'>ClinicalTrials.gov</a> </li></ul>
24
NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05667532
Contrast-Enhanced Mammograms for Women with Dense Breasts
The C-MERIT Screening Cohort: Contrast-enhanced Mammography for Breast Cancer Screening and Risk Assessment in Women With Dense Breasts Scientific Title
Purpose
To compare the ability of contrast-enhanced mammography (CEM) and standard mammography to detect breast cancer in women with dense breasts.
Who is this for?
Women ages 30 to 75 with dense breasts and no personal history of DCIS or breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast-enhanced mammogram</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for treatment schedule</i></p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard mammography (mammogram) is a breast cancer screening procedure involving taking an X-ray picture of the breast.</li> <li class="seamTextUnorderedListItem">Contrast-enhanced mammography (CEM) includes an injection of contrast dye before the mammogram to detect and visualize cancer cells.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05667532' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://uvahealth.com/services/breast-screening/cem' target='_blank'>University of Virginia Health: Contrast-Enhanced Mammogram</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/breast/basic_info/mammograms.htm' target='_blank'>Centers for Disease Control and Prevention: Mammogram</a> </li></ul>
25
NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX
VISITS: 2 visits within 3 months
PHASE: NA
NCT ID: NCT05056844
Mammogram with Contrast to Detect Breast Cancer in Women with Abnormal Nipple Discharge
Contrast Enhanced Spectral Mammography (CESM) for the Evaluation of Pathologic Nipple Discharge: A Pilot Study Scientific Title
Purpose
To learn if contrast enhanced spectral mammography (CESM) is better than standard mammography for determining the cause of nipple discharge and detecting breast cancer.
Who is this for?
Women with abnormal fluid coming from the nipple (discharge) who receive care at MD Anderson Cancer Center in Houston, TX. You must not have been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast enhanced spectral mammography (CESM)</li> <li class="seamTextUnorderedListItem">Digital tomosynthesis mammography</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A mammogram is a breast cancer screening procedure involving taking an x-ray picture of the breast.</li> <li class="seamTextUnorderedListItem">Mammograms can identify areas of concern, but many areas (lesions) turn out to not be cancer.</li> <li class="seamTextUnorderedListItem">Contrast enhanced spectral mammography (CESM) is similar to standard mammography, but it includes an intravenous (by vein) injection of contrast, which makes tissue and blood vessels more visible in scans.</li> <li class="seamTextUnorderedListItem">CESM may increase the chance of finding breast cancers and decrease unnecessary biopsies.</li> <li class="seamTextUnorderedListItem">A breast tomosynthesis (DBT) mammogram takes multiple pictures of your breast from more angles than a standard mammogram.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05056844' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mdanderson.org/cancerwise/what-is-a-contrast-enhanced-mammogram.h00-159701490.html' target='_blank'>MD Anderson Cancer Center: What is a Contrast-Enhanced Mammogram?</a> </li><li class='seamTextUnorderedListItem'><a href='https://my.clevelandclinic.org/health/diagnostics/15939-digital-breast-tomosynthesis-and-breast-cancer-screening' target='_blank'>Cleveland Clinic: Breast Tomosynthesis</a> </li></ul>
26
NEAREST SITE: 1643 miles
MD Anderson Cancer Center
Houston,TX
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05694559
Inherited Cancer Genetic Testing for Black Individuals and Families
Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics Scientific Title
Purpose
To connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.
Who is this for?
Black or African-American individuals over 18 years of age that live near Houston, Texas.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saliva collection kit to collect a saliva sample for genetic testing</li> <li class="seamTextUnorderedListItem">Screening form to assess your risk of hereditary breast cancer</li> <li class="seamTextUnorderedListItem">Counseling about genetic testing</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing looks for changes, sometimes called mutations or variants, in your DNA.</li> <li class="seamTextUnorderedListItem">You will also receive counseling about what genetic testing is, why you are eligible, how to receive genetic testing, and that you will be connected to a genetic counselor if you have a pathogenic mutation (PV) of a variant of unknown significance (VUS).</li> <li class="seamTextUnorderedListItem">You will also receive resources for family cascade genetic testing.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05694559' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/risk-factor/gene-mutations-genetic-testing/genetic-counseling-for-people-who-do-not-have-breast-cancer/' target='_blank'>Susan G. Komen: Genetic Testing for People Who Do Not Have Breast Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/genomics/disease/cascade_testing/index.htm' target='_blank'>Centers for Disease Control and Prevention: Cascade Testing</a> </li></ul>
27
NEAREST SITE: 1643 miles
Baylor College of Medicine
Houston,TX
VISITS: Coincides with biopsy
PHASE: NA
NCT ID: NCT06085833
New Method to Analyze Biopsy Tissue and Diagnose Breast Cancer
ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions (ANGEL) Scientific Title
Purpose
To study the ability of ARTIDIS ART-1 device, an experimental method of examining biopsy tissue, to predict tumor type, aggressiveness, and response to neoadjuvant (before surgery) treatment.
Who is this for?
People who are planning to receive a breast biopsy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast biopsy analyzed with ARTIDIS ART-1 device</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The standard method of examining tissue from a breast biopsy for the presence of cancer cells is to stain the tissue and look at it with a microscope.</li> <li class="seamTextUnorderedListItem">The ARTIDIS platform being tested in this study examines the physical properties and may reduce the amount of time for results.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06085833' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://artidis.com/' target='_blank'>ARTIDIS Biopsy Platform</a> </li></ul>
28
NEAREST SITE: 1643 miles
UT Health Houston
Houston,TX
VISITS: At least 2 visits within 1 year
PHASE: NA
NCT ID: NCT05349227
Virtual Health Coaching for People with Stage 0-IV Breast Cancer
Comprehensive Outcomes for After Cancer Health (COACH): The Feasibility and Impact of an mHealth Augmented Coaching Program for Self-Management in Cancer Survivors Scientific Title
Purpose
To study the use of virtual health coaching to improve well-being, including management of other health conditions, mental and social wellness, and healthy lifestyle behaviors.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer, and people without a history of breast cancer. If you have stage 0-III breast cancer, you must have completed treatment within the last year. If you have metastatic (stage IV) breast cancer, you must have been diagnosed with metastatic disease within the past year.
Full eligibility criteria
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- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Immediately Start Coaching</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Virtual health coaching, up to 4 times weekly, during first 6 months</li> <li class="seamTextUnorderedListItem">Provide stool samples, 2 times within 6 months</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires during second 6 months</li> <li class="seamTextUnorderedListItem">Wear a FitBit, 1 year</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Delayed Start Coaching</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires during first 6 months</li> <li class="seamTextUnorderedListItem">Provide stool samples, 2 times within 6 months</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Virtual health coaching, up to 4 times weekly, during second 6 months</li> <li class="seamTextUnorderedListItem">Wear a FitBit, 1 year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This program aims to support people's ability to manage their symptoms and their general wellness (including physical, mental, and social well-being, as well as following healthcare recommendations).</li> <li class="seamTextUnorderedListItem">Coaching consists of weekly calls and information about exercise, physical health, emotional health, and financial health.</li> <li class="seamTextUnorderedListItem">This study is also studying the relationship between symptoms and gut health and if coaching improves gut health.</li> <li class="seamTextUnorderedListItem">People that live in your household who do not have cancer will also be eligible to participate in this study.</li> <li class="seamTextUnorderedListItem">This trial is enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05349227' target='_blank'>ClinicalTrials.gov</a> </li></ul>
29
NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX
VISITS: 2 visits within 2 weeks
PHASE: NA
NCT ID: NCT05042687
Molecular Breast Imaging Scan for Women at High Risk of Breast Cancer
Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer Scientific Title
Purpose
To compare the accuracy of molecular breast imaging (MBI) to breast magnetic resonance imaging (MRI) to detect breast cancer.
Who is this for?
Women at high risk for breast cancer who are planning to receive a breast MRI.
Full eligibility criteria
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- What's being studied?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast MRI scan, 1 time</li> </ul> <p class="seamTextPara"> followed 2 weeks later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI) scan with technetium99m (Tc99m), by IV, 1 time</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Molecular breast imaging (MBI) is a method for detecting abnormal cells on a scan that uses injection of a radioactive tracer. Breast cancer cells take up this tracer more than normal cells, and this allows doctors to see the cancer cells on a scan.</li> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy rather than x-ray energy.</li> <li class="seamTextUnorderedListItem">Technetium99m (Tc99m) is the tracer used in this study.</li> <li class="seamTextUnorderedListItem">If you do not speak English, an interpreter will help you translate.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05042687' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/tests-procedures/molecular-breast-imaging/about/pac-20394710' target='_blank'>Mayo Clinic: Molecular Breast Imaging</a> </li></ul>
30
NEAREST SITE: 1643 miles
MD Anderson Cancer Center
Houston,TX
VISITS: 1-2 visits
PHASE: NA
NCT ID: NCT06373354
Comparing 2 Types of Mammograms to Detect Changes in the Breast
Comparison of Conspicuity of Masses and Architectural Distortions Between Wide- and Narrow-angle Digital Breast Tomosynthesis Systems Scientific Title
Purpose
To compare the ability of 2 types of mammograms to detect changes in the breast.
Who is this for?
Women who are planning to receive a mammogram at MD Anderson Cancer Center.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Digital breast tomosynthesis (DBT), 1-2 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Digital breast tomosynthesis (DBT) is an advanced mammogram that takes multiple pictures of your breast from more angles than a standard mammogram.</li> <li class="seamTextUnorderedListItem">Of the 2 different types of DBT mammograms, 1 may be better than the other for detecting changes in the breast.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06373354' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://my.clevelandclinic.org/health/diagnostics/15939-digital-breast-tomosynthesis-and-breast-cancer-screening' target='_blank'>Cleveland Clinic: Digital Breast Tomosynthesis</a> </li></ul>
31
NEAREST SITE: 1643 miles
The University of Texas MD Anderson Cancer Center
Houston,TX
VISITS: 3 visits within 2 years
PHASE: NA
NCT ID: NCT05625659
Imaging to Improve Breast Cancer Screening in Women With Dense Breasts
Comparison of Breast Cancer Screening With Dual-Energy Contrast-Enhanced Spectral Mammography to Digital Breast Tomosynthesis in Women With Dense Breasts (Contrast Mammography Imaging Screening Trial Scientific Title
Purpose
To study if dual-energy contrast-enhanced spectral mammography (CESM) can improve breast cancer screening in women with dense breasts.
Who is this for?
Women 45-74 years old with dense breasts.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard mammogram, 2 times within 1 year</li> <li class="seamTextUnorderedListItem">Contrast-enhanced spectral mammography (CESM), 2 times within 1 year</li> <li class="seamTextUnorderedListItem">Imaging contrast, by IV, 2 times within 1 year</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Email, text, or phone call</li> <li class="seamTextUnorderedListItem">Return to standard mammography for breast cancer screening</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Dual-energy contrast-enhanced spectral mammography (CESM) uses contrast to improve detection of breast cancer compared to standard mammograms.</li> <li class="seamTextUnorderedListItem">Some cancers, such as those present in dense breast tissue, may be visible on CESM but not on a standard mammogram.</li> <li class="seamTextUnorderedListItem">Breast cancer is harder to see on a mammogram of dense breasts.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05625659' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://densebreast-info.org/screening-technologies/contrast-enhanced-mammography/#:~:text=CEM%20can%20be%20used%20to,or%20abnormalities%20seen%20on%20mammograms.' target='_blank'>Dense Breast Info.org: Contrast-Enhanced Mammograms</a> </li><li class='seamTextUnorderedListItem'><a href='https://densebreast-info.org/for-patients/5-facts-you-should-know/' target='_blank'>Dense Breast Info.org: What to Know About Dense Breasts</a> </li></ul>
32
NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05649072
Genetic Testing and Counseling for Women in Texas
Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics. Scientific Title
Purpose
To provide genetic testing and counseling to underserved women at risk for breast cancer.
Who is this for?
Women ages 40 to 74 who live in Texas, do not have health insurance, and are planning to receive a mammogram through the Project VALET program.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Genetic testing and counseling</li> <li class="seamTextUnorderedListItem">Questionnaire</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will provide a saliva sample for genetic testing when you arrive at your Project VALET mammogram appointment.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05649072' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mdanderson.org/about-md-anderson/business-legal/office-of-health-policy/project-valet.html#:~:text=Project%20VALET%20(Providing%20Valuable%20Area,are%20patients%20in%20participating%20clinics.' target='_blank'>MD Anderson Cancer Center: Project VALET Mammogram Screening</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/genetic-testing' target='_blank'>Breastcancer.org: Genetic Testing</a> </li></ul>
33
NEAREST SITE: 1683 miles
The University of Texas Medical Branch, Galveston
Galveston,TX
VISITS: 2 visits in 3 months
PHASE: NA
NCT ID: NCT06395506
Exercise and Creatine Supplement to Increase Strength of Women After Chemotherapy
An Open-label Randomized Trial of Exercise ± Creatine Supplementation to Augment the Adaptations of Exercise Training in Cancer Survivors (THRIVE) Scientific Title
Purpose
To study if creatine supplements can help people with breast cancer respond more quickly to exercise and improve strength.
Who is this for?
Women with stage I, stage II, and stage III breast cancer who have completed chemotherapy in the last 6 months, and women who have not been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Creatine and Exercise</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Creatine, by mouth, daily for 3 months</li> <li class="seamTextUnorderedListItem">Exercise sessions, virtual, 3 times every week for 3 months</li> <li class="seamTextUnorderedListItem">Wear a Fitbit</li> <li class="seamTextUnorderedListItem">Strength and walking tests, 2 times in 3 months</li> <li class="seamTextUnorderedListItem">DEXA scan, 2 times in 3 months</li> <li class="seamTextUnorderedListItem">MRI scan, 2 times in 3 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Exercise Only</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise sessions, virtual, 3 times every week for 3 months</li> <li class="seamTextUnorderedListItem">Wear a Fitbit</li> <li class="seamTextUnorderedListItem">Strength and walking tests, 2 times in 3 months</li> <li class="seamTextUnorderedListItem">DEXA scan, 2 times in 3 months</li> <li class="seamTextUnorderedListItem">MRI scan, 2 times in 3 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is comparing information from women who have never had breast cancer to women who have completed chemotherapy for breast cancer.</li> <li class="seamTextUnorderedListItem">Creatine is a supplement that may help you improve strength and physical function.</li> <li class="seamTextUnorderedListItem">A Fitbit is device you wear on your wrist that tracks your physical activity.</li> <li class="seamTextUnorderedListItem">DEXA scans use x-ray energy to measure bone density (thickness and strength of bones).</li> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy rather than x-ray energy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06395506' target='_blank'>ClinicalTrials.gov</a> </li></ul>
34
NEAREST SITE: 1739 miles
Washington University School of Medicine
St Louis,MO
VISITS: Up to 24 visits
PHASE: NA
NCT ID: NCT04354064
Collecting Blood Samples from People Without Cancer to Create Blood Test to Detect Cancer Recurrence
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors Scientific Title
Purpose
To create a circulating tumor DNA (ctDNA) test to detect cancer recurrence using blood samples from people who do not have cancer.
Who is this for?
People who do not have a history of breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood samples, up to 24 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Circulating tumor DNA (ctDNA) are small bits of cancer cell DNA in the blood.</li> <li class="seamTextUnorderedListItem">Detecting ctDNA can help detect cancer recurrence (cancer coming back) earlier.</li> <li class="seamTextUnorderedListItem">People who have cancer may have ctDNA in their blood.</li> <li class="seamTextUnorderedListItem">People who do not have cancer should not have ctDNA in their blood. Blood samples from these people are called controls.</li> <li class="seamTextUnorderedListItem">Blood samples from people who do not have cancer are needed to compare to blood samples from people who have cancer.</li> <li class="seamTextUnorderedListItem">In this study, researchers will use samples from people who do have cancer that were collected in other studies.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04354064' target='_blank'>ClinicalTrials.gov</a> </li></ul>
35
NEAREST SITE: 1739 miles
Washington University School of Medicine
St Louis,MO
VISITS: 1 or 2 visits
PHASE: NA
NCT ID: NCT06981208
Artificial Intelligence-Generated Education About Breast Reconstruction for Stage 0-III Breast Cancer or People at High Risk for Breast Cancer
ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and Satisfaction Scientific Title
Purpose
To study the usefulness of artificial intelligence-generated patient education about breast reconstruction options.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, or stage III breast cancer, or people at high risk for breast cancer, who are planning to receive a mastectomy and a consultation about breast reconstruction surgery options.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education generated by ChatGPT about breast reconstruction </li> <li class="seamTextUnorderedListItem">Survey</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard education about breast reconstruction</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">For the experimental group, participants will receive ChatGPT-generated patient-tailored education about breast reconstruction options.</li> <li class="seamTextUnorderedListItem">For the control group, participants will receive standard patient education that includes a description of breast reconstruction options, including which option is most suitable, as well as a description of the risk of complications and expected recovery after surgery.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06981208' target='_blank'>ClinicalTrials.gov</a> </li></ul>
36
NEAREST SITE: 1814 miles
Rush University College of Nursing
Sugar Grove,IL
VISITS: 2 visits within 6 months
PHASE: NA
NCT ID: NCT06827704
Dance Program to Improve Physical Health and Reduce the Risk of Breast Cancer for South Asian Indian Immigrant Women
Physical Activity Targeting Metabolic Syndrome for Prevention of Breast Cancer in South Asian Indian Immigrant Women (MetS-BC) Scientific Title
Purpose
To improve physical activity and outcomes related to high blood pressure, diabetes, abnormal lipid levels, and obesity for reducing the risk of breast cancer in South Asian Indian immigrant women.
Who is this for?
South Asian Indian immigrant women, age 40-65 years, who do not have breast cancer, are physically inactive, and speak Hindi.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 4 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Wear a Fitbit</li> <li class="seamTextUnorderedListItem">Treatment plan to increase physical activity</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Body measurements, 2 times within 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Bollywood-style group dance, virtual, 1-hour sessions, twice a week for 6 months</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Body measurements, 2 times within 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Wear a Fitbit</li> <li class="seamTextUnorderedListItem">Treatment plan to increase physical activity</li> <li class="seamTextUnorderedListItem">Bollywood-style group dance, virtual, 1-hour sessions, twice a week for 6 months</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Body measurements, 2 times within 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 4</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">No intervention</li> <li class="seamTextUnorderedListItem">Blood tests, 2 times within 6 months</li> <li class="seamTextUnorderedListItem">Body measurements, 2 times within 6 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer develops an average of 5-10 years earlier in South Asian Indian immigrant women than in white women.</li> <li class="seamTextUnorderedListItem">The risk of breast cancer is more than twice as high in South Asian Indian immigrant women with high blood pressure, diabetes, abnormal lipid levels, and obesity than in white women with these conditions.</li> <li class="seamTextUnorderedListItem">This study aims to use a culturally appropriate exercise program to improve physical activity, blood pressure, diabetes, lipid levels, and obesity to reduce the risk of breast cancer in South Asian Indian immigrant women.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06827704' target='_blank'>ClinicalTrials.gov</a> </li></ul>
37
NEAREST SITE: 1832 miles
Medical College of Wisconsin
Milwaukee,WI
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06383026
Understanding Breast Cancer Screening Experiences for Transgender and Gender-Diverse People
Understanding Breast Cancer Risk and Screening in Transgender and Gender-Diverse Persons Through a Pilot Breast Cancer Screening Program Scientific Title
Purpose
To study the breast cancer screening perceptions and experiences of transgender and gender-diverse people and understand factors that make breast cancer screening more difficult.
Who is this for?
Transgender and gender-diverse people at least 30 years old who have received gender-affirming hormone therapy. You must not have a history of breast cancer or a known genetic mutation that increases your risk for breast cancer.
Full eligibility criteria
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- What's being studied?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mammogram</li> <li class="seamTextUnorderedListItem">Whole breast ultrasound</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Transgender and gender-diverse people may experience barriers and non-equitable treatment by healthcare professionals that make receiving breast cancer screening more difficult.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06383026' target='_blank'>ClinicalTrials.gov</a> </li></ul>
38
NEAREST SITE: 1853 miles
Mile Square Health Center
Chicago,IL
VISITS: 3 visits
PHASE: NA
NCT ID: NCT05841355
Empowering Latina Women to Receive Breast Cancer Screening
Empowering Latinas to Obtain Guideline Concordant Screenings Scientific Title
Purpose
This trial will study a new way to educate Latina women about the importance of breast cancer screening.
Who is this for?
Latina women 50-74 years old who have not had a mammogram in the last 2 years and have not been diagnosed with breast cancer.
Full eligibility criteria
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- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">New breast cancer screening education, 3 sessions</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard breast cancer screening education, 3 sessions</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for trial schedule</i></p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Latina women are less likely than other groups to receive breast cancer screening.</li> <li class="seamTextUnorderedListItem">Education sessions cover topics such as breast cancer information, screening, personal stories, lifestyle factors, role playing, and individual action plans.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05841355' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.bcrf.org/blog/hispanic-latina-breast-cancer-facts-statistics/' target='_blank'>Breast Cancer Research Foundation: Breast Cancer and Screening in Latina Women</a> </li></ul>
39
NEAREST SITE: 2054 miles
University of Michigan Rogel Cancer Center
Ann Arbor,MI
VISITS: Number of visits unavailable
PHASE: II
NCT ID: NCT06617455
Fezolinetant to Reduce Hot Flashes and Night Sweats for Women Receiving Hormone Therapy
Phase 2 Randomized, Cross-over Trial of Fezolinetant for Treatment of Vasomotor Symptoms in Patients Taking Endocrine Therapy (VEnT) Scientific Title
Purpose
To study if fezolinetant can reduce hot flashes and night sweats for women receiving hormone therapy.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III hormone receptor positive (ER+ and/or PR+) breast cancer or women at high risk of breast cancer who are receiving or planning to receive tamoxifen (Nolvadex®), letrozole (Femara®), anastrozole (Arimidex®), or exemestane (Aromasin®) hormone therapy. You must be experiencing hot flashes and/or night sweats.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Fezolinetant First</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Fezolinetant, by mouth, daily for 1 month</li> <li class="seamTextUnorderedListItem">Blood tests</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> followed 2 weeks later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for fezolinetant, by mouth, daily for 1 month</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Placebo First</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for fezolinetant, by mouth, daily for 1 month</li> <li class="seamTextUnorderedListItem">Blood tests</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> followed 2 weeks later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Fezolinetant, by mouth, daily for 1 month</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Hormone therapy is effective for lowering the risk of breast cancer and preventing breast cancer recurrence but can cause bothersome side effects including hot flashes and night sweats, called vasomotor symptoms.</li> <li class="seamTextUnorderedListItem">Fezolinetant is used to manage these symptoms in postmenopausal women and may also work in people with breast cancer who are receiving hormone therapy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06617455' target='_blank'>ClinicalTrials.gov</a> </li></ul>
40
NEAREST SITE: 2108 miles
Ohio State University Comprehensive Cancer Center
Columbus,OH
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06666192
Cancer Screening and Education for Women in Central Ohio
A Multi-Level Intervention for Improving Screening Rates of Breast, Cervical and Colorectal Cancer in Women in Low-Income Communities Scientific Title
Purpose
To study how well the SCREEN Community Program increases cancer screening for low income and un/underinsured women in Central Ohio.
Who is this for?
Women who live in Central Ohio who are low income and do not have insurance (uninsured) or do not have enough insurance (underinsured).
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following as part of the SCREEN Community Program: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cancer screening and follow-up</li> <li class="seamTextUnorderedListItem">Cancer screening educational materials</li> <li class="seamTextUnorderedListItem">Screening recommendations, by mail and during in-person visits</li> <li class="seamTextUnorderedListItem">Access to educational website</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial involves screening for breast, cervical, and colorectal cancer.</li> <li class="seamTextUnorderedListItem">Cancer screening can detect cancer when treatment is less intensive and more successful.</li> <li class="seamTextUnorderedListItem">However many low income and un/underinsured women do not have access to health care and screenings.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06666192' target='_blank'>ClinicalTrials.gov</a> </li></ul>
41
NEAREST SITE: 2108 miles
Ohio State University Comprehensive Cancer Center
Columbus,OH
VISITS: 7-9 visits within 3 months
PHASE: NA
NCT ID: NCT06635005
Low Insulin Diet to Reduce Breast Cancer Risk in High Risk Women
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women Scientific Title
Purpose
To study whether a diet that leads to low insulin levels can reduce the risk of breast cancer.
Who is this for?
Women at least 45 years old or postmenopausal women with a BMI of 25-35 who are at high risk for breast cancer. You must receive care at the Ohio State University Comprehensive Cancer Center (OSUCCC) Stefanie Spielman Comprehensive Breast Center (SSCBC) high risk breast clinic.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Nutrition education sessions, weekly for 1.5 months</li> <li class="seamTextUnorderedListItem">Nutrition counseling, in person or virtual, 3 times within 3 months</li> <li class="seamTextUnorderedListItem">Wear an activity tracker</li> <li class="seamTextUnorderedListItem">Blood, stool, and urine samples</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The diet in this study is designed to lower insulin levels.</li> <li class="seamTextUnorderedListItem">The diet is moderately low in total fat and saturated fat, low in protein from animal foods but high in protein from plant sources, high in fruits and vegetables, high in whole grains, and high in dietary fiber.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06635005' target='_blank'>ClinicalTrials.gov</a> </li></ul>
42
NEAREST SITE: 2139 miles
Emory University Hospital/Winship Cancer Institute
Atlanta,GA
VISITS: 1-2 visits in up to 6 years
PHASE: NA
NCT ID: NCT06760507
Education and Screening for Cancers Related to BRCA for Women in Southwest Georgia
Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics (RSPH5973-23) Scientific Title
Purpose
To study the ability of the GA CORE family history screening program to increase screening for cancers related to the BRCA gene.
Who is this for?
Women at least 25 years old who receive care in southwest Georgia.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education about breast cancer risk</li> <li class="seamTextUnorderedListItem">Follow up to encourage cancer screening (if recommended)</li> <li class="seamTextUnorderedListItem">Standard genetic testing results and follow up</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Help from nurses about screening</li> <li class="seamTextUnorderedListItem">Standard genetic testing results and follow up</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Simple, low cost family history screening can identify families at high risk for cancers related to the BRCA gene.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06760507' target='_blank'>ClinicalTrials.gov</a> </li></ul>
43
NEAREST SITE: 2240 miles
The Howard Center for Women's Health
Tifton,GA
VISITS: 2 visits in 1 month
PHASE: NA
NCT ID: NCT05036096
Cone Beam CT Imaging Scans for Breast Cancer Screening and Diagnosis
Cone Beam Breast CT for Breast Cancer Screening Scientific Title
Purpose
To study the usefulness of cone beam CT scans for breast screening and diagnosis.
Who is this for?
Women at least 40 years old who are planning to receive a screening mammogram, or women at least 30 years old who are planning to receive a diagnostic mammogram.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mammogram</li> </ul> <p class="seamTextPara"> followed within 1 month by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cone beam CT scan</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial is studying cone beam CT scans, a type of imaging scan that is obtained with a similar x-ray exposure as a standard mammogram.</li> <li class="seamTextUnorderedListItem">During a cone beam CT scan, you lay stomach-down on the exam table, and the image of your breast is obtained in a few seconds.</li> <li class="seamTextUnorderedListItem">A previous study showed that this imaging method results in better breast images than a standard mammogram.</li> <li class="seamTextUnorderedListItem">This study is finding additional information about the usefulness of this type of scan.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05036096' target='_blank'>ClinicalTrials.gov</a> </li></ul>
44
NEAREST SITE: 2299 miles
Roswell Park Cancer Institute
Buffalo,NY
VISITS: 1 visit
PHASE: NA
NCT ID: NCT06456411
Brain Scan and Virtual Reality to Decrease Pain for People with Stage 0-IV Breast Cancer
Real-Time Evaluation of Severity of Perceived Pain in Patients With Cancer by Using Functional Near-Infrared Spectroscopy (fNIRS), and Investigation of Pain Relief Utilizing Virtual Reality Technologies Scientific Title
Purpose
To study whether a virtual reality relaxation program can decrease pain and if this can be seen in the brain with a functional near-infrared spectroscopy scan.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are experiencing pain from treatment, and people who do not have breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Virtual Reality and Scan</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Functional near-infrared spectroscopy scan, 1 time</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Virtual reality, 1 time, at least 15 minutes</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Scan Only</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Functional near-infrared spectroscopy scan, 1 time</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Functional near-infrared spectroscopy is a non-invasive type of imaging scan that can show pictures of the brain and brain activity.</li> <li class="seamTextUnorderedListItem">Virtual reality (VR) is a computer-generated experience that simulates the 3D environment.</li> <li class="seamTextUnorderedListItem">Virtual reality relaxation programs may help relieve pain in people with cancer who are receiving treatment. Relief of pain may be seen on a functional near-infrared spectroscopy scan.</li> <li class="seamTextUnorderedListItem">Results from people who do not have breast cancer will be compared to results from people with breast cancer.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06456411' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.techtarget.com/whatis/definition/virtual-reality' target='_blank'>Tech Target: What is Virtual Reality?</a> </li></ul>
45
NEAREST SITE: 2299 miles
Roswell Park Cancer Institute
Buffalo,NY
VISITS: 1 visit
PHASE: NA
NCT ID: NCT03897270
Photoacoustic Imaging (A Scan That Uses Waves and Light) to Study Breast Tissue and Tumors in Women
Photoacoustic Imaging of Human Breast Scientific Title
Purpose
To study breast tissue and tumors by using photoaccoustic imaging (a type of scan that uses sound and light to study tissue).
Who is this for?
Women diagnosed with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have received or are planning to receive a breast MRI. You may also enroll if you have not been diagnosed with breast cancer but are scheduled to receive an MRI to look at a suspicious mass (lump) in your breast.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Photoacoustic imaging of the breast, for about 30 minutes, once</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">You may choose to repeat this process up to 10 times (on separate days)</i></p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Research shows that mammograms are more difficult to read in women with dense breasts.</li> <li class="seamTextUnorderedListItem">Photoacoustic imaging is a type of scan that uses sound and light to study breast tissue.</li> <li class="seamTextUnorderedListItem">Researchers are studying whether photoacoustic imaging makes it easier to see tumors in women with dense breasts.</li> <li class="seamTextUnorderedListItem">They are also studying if they can learn anything new about breast tissue and tumors with this experimental imaging technique.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03897270' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://en.wikipedia.org/wiki/Photoacoustic_imaging' target='_blank'>Wikipedia: Photoacoustic Imaging</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/types/breast/breast-changes/dense-breasts' target='_blank'>NCI Breast Cancer: Dense Breasts</a> </li><li class='seamTextUnorderedListItem'><a href='https://dmm.biologists.org/content/12/7/dmm039636' target='_blank'>Journal Article: Photoacoustic Imaging as a Tool to Probe the Tumour Microenvironment</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005545/' target='_blank'>Journal Article: Photoacoustic Imaging of Breast Cancer</a> </li></ul>
46
NEAREST SITE: 2325 miles
Hawaii Radiology Associates, LTD (East Hawaii Women's Imaging Center)
Hilo,HI
VISITS: 1 visit
PHASE: NA
NCT ID: NCT05369546
Improving Digital Breast Tomosynthesis to Better Identify Breast Lesions That Require a Biopsy
Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis Scientific Title
Purpose
To improve the use of digital breast tomosynthesis (DBT) to better identify suspicious breast lesions that need to be biopsied.
Who is this for?
Women with a suspicious area on a mammogram who have not yet had a biopsy. You must not have a history of breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Digital breast tomosynthesis (DBT), 1 time</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Most breast biopsies (71%) in the US do not result in a diagnosis of cancer. This means that many biopsies are unnecessary.</li> <li class="seamTextUnorderedListItem">A new way to use digital breast tomosynthesis (DBT) may reduce unnecessary biopsies.</li> <li class="seamTextUnorderedListItem">Digital breast tomosynthesis (DBT) is an advanced mammogram that takes multiple pictures of your breast from more angles than a standard mammogram.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05369546' target='_blank'>ClinicalTrials.gov</a> </li></ul>
47
NEAREST SITE: 2352 miles
University of Rochester
Rochester,NY
VISITS: 6 visits over 3-5 months
PHASE: NA
NCT ID: NCT03137095
Memory Problems During Chemotherapy in People with Stage I-III Breast Cancer
Longitudinal Pilot Mechanistic Study of the Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients and Non-Cancer Control Participants Scientific Title
Purpose
To study if and how your cognitive functioning skills, like memory and concentration, change as you receive chemotherapy.
Who is this for?
Women with newly diagnosed stage I, stage II, or stage III breast cancer who are planning to receive chemotherapy, and women who do not have breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will undergo the following over 3-5 months: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">6 cognitive tests, during chemotherapy and 1 month after chemotherapy</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cognitive tests study your cognition, which is your ability to think.</li> <li class="seamTextUnorderedListItem">Women without breast cancer will also be enrolled for comparison.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03137095' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/managing-cancer/side-effects/changes-in-mood-or-thinking/chemo-brain.html' target='_blank'>American Cancer Society: What is Chemo Brain?</a> </li></ul>
48
NEAREST SITE: 2376 miles
UVA Breast Care Center
Charlottesville,VA
VISITS: 1 visit
PHASE: NA
NCT ID: NCT04904757
Contrast-Enhanced Mammograms for Breast Cancer Screening
Willingness of Women to Undergo a Contrast-enhanced Spectral Mammography (CESM) for Breast Cancer Screening and Their Experience Before and After CESM Scientific Title
Purpose
To study if women receive contrast enhanced spectral mammograms (CESM) as their yearly breast screening test instead of standard of care mammograms.
Who is this for?
Women 40-69 years old who have mammogram results showing dense breasts within the last 2 years and are planning to receive a screening mammogram.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Contrast-enhanced spectral mammography (CESM)</li> <li class="seamTextUnorderedListItem">Questionnaire</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A mammogram is a breast cancer screening procedure involving taking an x-ray picture of the breast.</li> <li class="seamTextUnorderedListItem">Contrast enhanced spectral mammograms (CESM) are similar to standard mammograms, but they include an intravenous (by vein) injection of contrast, which makes tissue and blood vessels more visible in scans.</li> <li class="seamTextUnorderedListItem">For CESMs, 2 images are taken almost at the same time after the contrast is given. The first image is similar to a regular mammogram. The second image shows areas that take up the contrast and show increased blood flow, which may indicate an area of concern.</li> <li class="seamTextUnorderedListItem">CESM is FDA approved for breast cancer detection, but its use is low.</li> <li class="seamTextUnorderedListItem">CESM is used most often when additional information is needed after a standard mammogram.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04904757' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mdanderson.org/cancerwise/what-is-a-contrast-enhanced-mammogram.h00-159701490.html' target='_blank'>MD Anderson Cancer Center: What is a Contrast-Enhanced Mammogram?</a> </li></ul>
49
NEAREST SITE: 2382 miles
University of North Carolina at Chapel Hill
Chapel Hill,NC
VISITS: Up to 3 visits
PHASE: NA
NCT ID: NCT06878547
Ultrasound for High-Risk Women or Women with Stage II-III Breast Cancer
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients Scientific Title
Purpose
To study the relationship between tissue characteristics measured with ultrasound and breast tumors and response to chemotherapy.
Who is this for?
Women with a suspicious breast lesion or women with stage II or stage III breast cancer who plan to receive treatment before surgery (neoadjuvant) and who receive care at the University of North Carolina Hospitals.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ultrasound scan, up to 3 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The tissue characteristics measured in this study may be biomarkers of cancer and response to treatment before surgery.</li> <li class="seamTextUnorderedListItem">Ultrasounds use sound waves to produce images of structures within your body.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06878547' target='_blank'>ClinicalTrials.gov</a> </li></ul>
50
NEAREST SITE: 2383 miles
Mayo Clinic Breast Clinic
Jacksonville,FL
VISITS: 1-2 visits
PHASE: NA
NCT ID: NCT06512350
Breath Samples to Detect Breast Cancer
Using Infrared Spectroscopy to Analyze Volatile Organic Compounds in the Breath of Patients With Breast Cancer Scientific Title
Purpose
To study if breath samples help detect breast cancer and if there are substances in the breath that are associated with breast cancer.
Who is this for?
Women 40-74 years old with dense breasts who are planning to receive a standard of care biopsy or MRI scan. You must not have been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breathe into a device, 1-2 times</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Researchers will collect breath samples before your biopsy or MRI scan.</li> <li class="seamTextUnorderedListItem">If your biopsy or MRI scan results in a breast cancer diagnosis, a second sample will also be collected after treatment.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish and French.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06512350' target='_blank'>ClinicalTrials.gov</a> </li></ul>
51
NEAREST SITE: 2383 miles
Mayo Clinic in Florida
Jacksonville,FL
VISITS: Coincides with routine care
PHASE: NA
NCT ID: NCT06783179
Studying Complications After Surgery for Women with Stage I-III Breast Cancer
Postoperative Outcomes and Patient Satisfaction for Patients Admitted to the Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement Scientific Title
Purpose
To study differences in complications after surgery based on where people receive care after surgery.
Who is this for?
Women with stage I, stage II, or some stage III breast cancer or women at high risk for breast cancer who received a mastectomy with reconstruction at Mayo Clinic in Jacksonville, FL.
Full eligibility criteria
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Surveys</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">After surgery at Mayo Clinic, people are admitted to the hospital, discharged (sent home) from the hospital, or stay at the Mayo Clinic Care Hotel.</li> <li class="seamTextUnorderedListItem">The Care Hotel offers people a comfortable environment to receive in-person and virtual nursing care in a hotel setting.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06783179' target='_blank'>ClinicalTrials.gov</a> </li></ul>
52
NEAREST SITE: 2383 miles
Mayo Clinic in Florida
Jacksonville,FL
VISITS: At least 1 visit within 10 years
PHASE: NA
NCT ID: NCT05755269
Genetic Risk of Breast Cancer for African American and Hispanic Women
Genetic Risk Estimation in Breast Cancer and Assessing Health Disparities Scientific Title
Purpose
To study whether adding a genetic risk assessment to standard breast cancer risk assessment tools helps African American and Hispanic women make more informed decisions about breast cancer screening and prevention.
Who is this for?
African American/Black or Hispanic/Latinx women 30-75 years old with lobular carcinoma in situ (LCIS) or women at risk of breast cancer, including with a history of abnormal biopsy results. You must not have taken drugs to prevent breast cancer for longer than 6 months, received a mastectomy to reduce your risk of breast cancer, or have a breast cancer mutation such as BRCA1/2, PALB2, ATM, or CHEK2.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood sample for genetic/genomic testing</li> <li class="seamTextUnorderedListItem">Surveys, 2 times in 6 months, then every year for 10 years</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will receive your genetic testing results and your risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Traditional breast cancer risk assessments include family history, reproductive history, and breast density.</li> <li class="seamTextUnorderedListItem">This information can be combined with genetic information to provide a 10 year and lifetime risk for breast cancer.</li> <li class="seamTextUnorderedListItem">Including genetics with traditional screening techniques may help minority women make more informed decisions about screening and prevention strategies for breast cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05755269' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/about-breast-cancer#section-breast-cancer-risk' target='_blank'>Breastcancer.org: Breast Cancer Risk</a> </li></ul>
53
NEAREST SITE: 2406 miles
The University of North Carolina
Chapel Hill,NC
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06817226
Designing a Breast Reconstruction Decision Making Tool for Latinx Women
Cultural and Linguistic Adaptation of a Breast Reconstruction Decision Tool (BREASTChoice) Scientific Title
Purpose
To study the best cultural and language options for making the BREASTChoice decision aid available in Spanish.
Who is this for?
Latina/Latinx women who have stage 0 (DCIS), stage I, stage II, or some stage III breast cancer or are at high risk for breast cancer and received a mastectomy in the last 8 years. You must prefer to speak Spanish at home.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">BREASTChoice decision aid</li> <li class="seamTextUnorderedListItem">Interviews</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast reconstruction can improve quality of life and body image after mastectomy.</li> <li class="seamTextUnorderedListItem">Spanish speaking Latinx people are less likely to undergo reconstruction, meet with a reconstructive surgeon, or receive enough information.</li> <li class="seamTextUnorderedListItem">BREASTChoice is a tool that helps people make decisions about breast reconstruction.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06817226' target='_blank'>ClinicalTrials.gov</a> </li></ul>
54
NEAREST SITE: 2430 miles
Virginia Commonwealth University
Richmond,VA
VISITS: 3 visits within 4 months
PHASE: NA
NCT ID: NCT05130606
Video Versus Fact Sheet to Increase Genetic Counseling and Testing for Latina Women With Stage 0-IV Breast Cancer or High-Risk Women
Testing a Narrative Intervention to Enhance Genetic Counseling and Testing (CONTIGO) Scientific Title
Purpose
To compare a culturally targeted video and a Spanish-language fact sheet for enhancing genetic counseling, increasing genetic testing, and improving psychosocial outcomes.
Who is this for?
Latina women with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer or healthy women with a family history of cancer that suggests hereditary breast and ovarian cancer who speak Spanish. You must not have received genetic counseling or testing.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Watch the video: <q>Is My Cancer Hereditary? Rosa Visits a Genetic Counselor,</q> virtual</li> <li class="seamTextUnorderedListItem">Surveys, 3 times within 4 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Read a fact sheet, virtual</li> <li class="seamTextUnorderedListItem">Surveys, 3 times within 4 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The culturally targeted video is in Spanish with English subtitles. It provides education about genetic counseling and testing and hereditary breast and ovarian cancer to at-risk Latinas.</li> <li class="seamTextUnorderedListItem">The fact sheet includes information about genes, breast cancer, risk factors for hereditary breast and ovarian cancer, genetic counseling and testing, and resources.</li> <li class="seamTextUnorderedListItem">All participants will be offered genetic counseling and testing.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05130606' target='_blank'>ClinicalTrials.gov</a> </li></ul>
55
NEAREST SITE: 2434 miles
Georgetown University
Washington D.C.,DC
VISITS: 1 month
PHASE: NA
NCT ID: NCT06892275
Education About Decision-Making for a Screening Breast MRI Scan for Black and/or Latina Women at High Risk for Breast Cancer
The FYI on MRI: A Multilevel Decision Support Intervention for Screening Breast MRI Scientific Title
Purpose
To study decision support methods about breast MRI.
Who is this for?
Black and/or Latina women with no personal history of breast cancer who have received a mammogram at Ralph Lauren Center (Washington, DC) and are at high risk for breast cancer.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Letter, by mail</li> <li class="seamTextUnorderedListItem">Decision aid, by email or mail</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Letter, by mail</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Women at high risk for breast cancer may benefit from a breast MRI scan in addition to a mammogram.</li> <li class="seamTextUnorderedListItem">This study provides information needed to help a woman decide about having a breast MRI scan.</li> <li class="seamTextUnorderedListItem">All participants will receive a letter with their estimated lifetime risk for breast cancer, information about screening breast MRI, and instructions for contacting a nurse practitioner.</li> <li class="seamTextUnorderedListItem">The decision aid in this study describes two different breast cancer screening plans: (1) yearly mammogram only; and (2) yearly mammogram plus yearly breast MRI. The decision aid provides balanced information about breast MRI, including its risks, limitations, and benefits. The decision aid will emphasize that there is no 'correct' decision and women should pick the plan that is right for them. </li> <li class="seamTextUnorderedListItem">Study materials are available in English and Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06892275' target='_blank'>ClinicalTrials.gov</a> </li></ul>
56
NEAREST SITE: 2437 miles
Adventhealth
Orlando,FL
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT07231159
Understanding Barriers to Follow-Up After a Positive Breast Cancer Screening Result
Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots Scientific Title
Purpose
To study a community-based outreach program for screening, diagnosis, and treatment of breast cancer.
Who is this for?
Women, age 40-74 years, who received a result of "positive" for breast cancer following screening.
Full eligibility criteria
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- What's being studied?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Referral for follow-up after receiving a <q>positive</q> breast cancer screening result</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is looking at differences between adults who accept or decline follow-up after a <q>positive</q> cancer screening result. The researchers are looking for factors that prevent or make it easier for someone to receive cancer screening, diagnosis, treatment, and clinical trial screening. They are also seeking to understand people's feelings towards navigators who may help people receive these services.</li> <li class="seamTextUnorderedListItem">This trial is enrolling people who were screened for other cancers.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07231159' target='_blank'>ClinicalTrials.gov</a> </li></ul>
57
NEAREST SITE: 2444 miles
Burnett School Biomedical Sciences
Orlando,FL
VISITS: 1 visit
PHASE: NA
NCT ID: NCT06068257
Blood Test to Detect Breast Cancer
Translational Utility of Tumor-Derived FGF19 in a Novel Blood-Based Endocrine Suppression Approach Scientific Title
Purpose
To help develop a blood test to detect breast cancer.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer and people who have not been diagnosed with breast cancer.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">1 fasting blood draw</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biomarkers are genes, molecules, or other features in a person that tell doctors something about that person’s health.</li> <li class="seamTextUnorderedListItem">FGF19 is a protein that is a possible biomarker for breast cancer. The amount of FGF19 in blood may be abnormal in people with breast cancer.</li> <li class="seamTextUnorderedListItem">The study will compare the amount of FGF19 in the blood of people with and without breast cancer.</li> <li class="seamTextUnorderedListItem">This study is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06068257' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis#:~:text=Complete%20blood%20count%20(CBC)&text=It%20can%20help%20diagnose%20some,health%20during%20and%20after%20treatment.' target='_blank'>National Cancer Institute: How Cancer Is Diagnosed</a> </li><li class='seamTextUnorderedListItem'><a href='https://med.ucf.edu/media/2023/03/Participant-Recruitment-Flyer-External_Version-1_Tumor-Derived-FGF19_PI-Deborah-Altomare.pdf' target='_blank'>UCF Study Information</a> </li></ul>
58
NEAREST SITE: 2446 miles
University of Central Florida
Orlando,FL
VISITS: No visits required
PHASE: NA
NCT ID: NCT07214883
Registry of Mammograms to Improve Artificial Intelligence Analysis of Scans
UCF MammoChat: An AI-Driven Platform for Personalized Breast Cancer Patient Support -Image Repository Scientific Title
Purpose
To develop artificial intelligence (AI) models to better read diagnostic mammograms.
Who is this for?
People who have received a mammogram.
Full eligibility criteria
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- What's involved?
- What's being studied?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide consent to donate your mammogram.</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Around half of women will receive a false positive mammogram result (a report of cancer when cancer is not actually present). This creates anxiety.</li> <li class="seamTextUnorderedListItem">Artificial intelligence (AI) may be able to better read mammograms to reduce false positive results. AI models need to be improved for different racial groups, age ranges, ethnicities, and different types of breast cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07214883' target='_blank'>ClinicalTrials.gov</a> </li></ul>
59
NEAREST SITE: 2539 miles
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge,NJ
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT06334354
Changes in Thinking and Memory Over Time for Women with Stage I-III Breast Cancer After Treatment
Cognitive Aging in Older Long-term Breast Cancer Survivors (TRAC) Scientific Title
Purpose
To study how differences in mental function develop over time in breast cancer survivors compared to people without a history of cancer.
Who is this for?
Women 65-80 years old with stage I, stage II, or stage III breast cancer who were diagnosed between 55-60 years old (5-25 years ago) and have completed treatment, and people who do not have a history of breast cancer.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online surveys</li> <li class="seamTextUnorderedListItem">Saliva (spit) sample, by mail</li> <li class="seamTextUnorderedListItem">Urine sample</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Problems with thinking such as problems with memory, attention, and information processing may occur in people who were previously treated for breast cancer compared to those without a history of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06334354' target='_blank'>ClinicalTrials.gov</a> </li></ul>
60
NEAREST SITE: 2554 miles
Hackensack Meridian Health
Totowa,NJ
VISITS: 1 visit
PHASE: NA
NCT ID: NCT07038785
Identification of Breast Cancer in Breath Samples By Trained Detection Dogs for Women Planning to Receive Breast Cancer Screening or Biopsy
A Double Blind Observational Study to Validate the SpotitEarly Test for the Detection of Breast Cancer (The PINK Study) Scientific Title
Purpose
To study whether trained detection dogs and artificial intelligence (AI) can identify breast cancer in a person's breath.
Who is this for?
Women planning to receive routine breast cancer screening (mammogram, ultrasound scan, MRI scan) or a breast biopsy.
Full eligibility criteria
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- What's being studied?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide a breath sample by breathing into a surgical mask</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Specially trained dogs may be able to smell breast cancer in a person's breath.</li> <li class="seamTextUnorderedListItem">You may also be asked to provide breath samples at home for up to 2 years.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07038785' target='_blank'>ClinicalTrials.gov</a> </li></ul>
61
NEAREST SITE: 2567 miles
Memorial Sloan Kettering Cancer Center (All protocol activites)
New York,NY
VISITS: 5 visits in 5 years
PHASE: NA
NCT ID: NCT06780176
Studying Breast Cancer Risk Factors and Outcomes for People in Florida
Genomic and Non-Genomic Factors Associated With Breast Cancer Risk Factors and Outcomes in a Diverse South Florida Population Scientific Title
Purpose
To understand why different people have different risks and outcomes for breast cancer.
Who is this for?
People who are planning to receive a biopsy at University of Miami, Sylvester Comprehensive Cancer Center, or Jackson Health Systems.
Full eligibility criteria
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- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Tissue sample during biopsy</li> <li class="seamTextUnorderedListItem">Blood sample, 2 times</li> <li class="seamTextUnorderedListItem">Surveys, 5 times</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial will study breast cancer risk factors and outcomes in a diverse population of people in South Florida.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06780176' target='_blank'>ClinicalTrials.gov</a> </li></ul>
62
NEAREST SITE: 2568 miles
NYU Langone Health
New York,NY
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT05742178
Support from a Community Health Worker to Increase Breast Cancer Screening in New York City
NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation Randomized Controlled Trial (NYC CONNECT) Scientific Title
Purpose
To study the effects of education materials and/or information delivered by community health workers to increase breast cancer screening.
Who is this for?
Women 50-74 years old with no history of breast cancer, who have not had a mammogram in the last 2 years, and who live in New York City.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Information from a community health worker about social services and breast cancer screening</li> <li class="seamTextUnorderedListItem">Education materials about cancer</li> <li class="seamTextUnorderedListItem">Surveys, 3 times within 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Information from a community health worker about social services</li> <li class="seamTextUnorderedListItem">Education materials about cancer</li> <li class="seamTextUnorderedListItem">Surveys, 3 times within 6 months</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Information from a community health worker about breast cancer screening (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Information delivered by a community health worker about breast cancer screening may increase screening.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish, Haitian-Creole, and Chinese Mandarin.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05742178' target='_blank'>ClinicalTrials.gov</a> </li></ul>
63
NEAREST SITE: 2569 miles
Mount Sinai
New York,NY
VISITS: Coincides with routine care
PHASE: NA
NCT ID: NCT04983875
Sharing Breast Arterial Calcification Results After Mammograms
Enhancing the Public Health Benefits of Mammography Screening by Informing Women of Both Breast Cancer and Breast Arterial Calcification Results: A Randomized Trial to Promote Cardiovascular Health Scientific Title
Purpose
To study the potential benefits of adding breast arterial calcification (BAC) results to the standard results letter women receive after mammography.
Who is this for?
Women at least 40 years old who are planning to receive a mammogram at a Mount Sinai breast radiology clinic.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive a letter after your mammogram with your breast arterial calcification (BAC) status</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times within 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive standard of care letter after your mammogram without your breast arterial calcification (BAC) status</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times within 6 months</li> </ul> <p class="seamTextPara"> followed 6 months later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive information about BAC status</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">In addition to detecting potential breast cancer, mammograms can also detect the presence of calcifications within the breast arteries (blood vessels). </li> <li class="seamTextUnorderedListItem">Those calcifications, called BAC, can be associated with a disease of the heart and blood vessels called coronary artery disease.</li> <li class="seamTextUnorderedListItem">Currently, women are not routinely told whether or not they have BAC.</li> <li class="seamTextUnorderedListItem">Previous research has suggested that patients would like to be informed about their BAC status.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04983875' target='_blank'>ClinicalTrials.gov</a> </li></ul>
64
NEAREST SITE: 2574 miles
Montefiore Medical Center
The Bronx,NY
VISITS: 1 visit
PHASE: NA
NCT ID: NCT03694756
Experimental Breast MRI Scan for People with Suspected Breast Cancer or Stage I-III Breast Cancer
TMEM-MRI: A Pilot Feasibility Study of Magnetic Resonance Imaging for Imaging of TMEM (Tumor Microenvironment of Metastasis) in Patients With Operable Breast Cancer Scientific Title
Purpose
To study the ability of TMEM-MRI, an experimental type of MRI scan, to detect breast cancer cells.
Who is this for?
People with a breast mass that is suspected to be breast cancer, or people with stage I, stage II, or some stage III breast cancer who have not yet received treatment.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">TMEM-MRI scan, 1 time</li> <li class="seamTextUnorderedListItem">Contrast agent, by IV, 1 time</li> <li class="seamTextUnorderedListItem">Biopsy (if you have not yet received one)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy rather than x-ray energy.</li> <li class="seamTextUnorderedListItem">Tumor Microenvironment of Metastasis - Magnetic Resonance Imaging (TMEM-MRI) scans are an experimental type of MRI scan that can detect tumor areas that are more likely to travel to other sites in the body.</li> <li class="seamTextUnorderedListItem">TMEM-MRI scans may be useful to identify tumors with a higher chance of coming back (recurrence) after treatment.</li> <li class="seamTextUnorderedListItem">TMEM-MRI scans may also be useful for studying the response to neoadjuvant (before surgery) treatment such as chemotherapy and hormone therapy.</li> <li class="seamTextUnorderedListItem">A contrast agent, also called a tracer, is a radioactive substance that can look for and attach to cancer cells.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03694756' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/breast-mri' target='_blank'>Breastcancer.org: Breast MRI</a> </li></ul>
65
NEAREST SITE: 2626 miles
Cheshire Medical Center
Keene,NH
VISITS: 3 visits within 1 month
PHASE: NA
NCT ID: NCT06522568
Virtual Mammogram Decision Tool for Healthy Women Age 39-49 Years
Toward Optimization of a Mammography Decision Aid and Clinician Communication Intervention Trial for Rural Settings Scientific Title
Purpose
To study the effectiveness of a virtual breast cancer screening decision aid called MyMammogram.
Who is this for?
Women, age 39-49 years, who are planning to visit their primary care doctor in the next month. You must not have breast cancer or have had a mammogram in the last year.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 3 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Use MyMammogram before doctor's appointment</li> <li class="seamTextUnorderedListItem">Surveys, 3 times</li> <li class="seamTextUnorderedListItem">Interview</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Use MyMammogram before doctor's appointment</li> <li class="seamTextUnorderedListItem">Your doctor will receive information from MyMammogram about your breast cancer risk</li> <li class="seamTextUnorderedListItem">Surveys, 3 times</li> <li class="seamTextUnorderedListItem">Interview</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">No intervention</li> <li class="seamTextUnorderedListItem">Surveys, 3 times</li> <li class="seamTextUnorderedListItem">Interview</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MyMammogram is a virtual education tool that can help you learn about your breast cancer risk and the role of mammograms in screening for breast cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06522568' target='_blank'>ClinicalTrials.gov</a> </li></ul>
66
NEAREST SITE: 2652 miles
UMass Medical School
Worcester,MA
VISITS: 1 visit
PHASE: NA
NCT ID: NCT05968157
Breast MRI Scans for Women at High Risk for Breast Cancer
MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick Scientific Title
Purpose
To study the use of MIRAI model (guidelines) to identify breast cancer risk.
Who is this for?
Women who are at high risk for breast cancer who have received a mammogram.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast MRI scan using MIRAI</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Identifying breast cancer risk is important for making screening decisions.</li> <li class="seamTextUnorderedListItem">The standard way of identifying breast cancer risk is called the Tyrer-Cuzick model (guidelines).</li> <li class="seamTextUnorderedListItem">In this trial, the experimental way of identifying breast cancer risk is called the MIRAI model (guidelines), which uses a type of artificial intelligence (AI) to study mammograms.</li> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy rather than x-ray energy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05968157' target='_blank'>ClinicalTrials.gov</a> </li></ul>
67
NEAREST SITE: 2693 miles
Dana Farber Cancer Institute
Boston,MA
VISITS: At least 2 visits within 4 months
PHASE: NA
NCT ID: NCT06322888
Exercise to Reduce the Risk of Breast Cancer for Women With Dense Breasts
Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D) Scientific Title
Purpose
To study how exercise might lower the risk of developing breast cancer by studying changes that occur in breast tissue and blood.
Who is this for?
Women 18-59 years old with dense breasts on a mammogram within the past year and exercise less than 1 hour every week. You must not have a history of breast cancer, be pregnant or breastfeeding, or be receiving hormonal birth control or hormone replacement therapy.
Full eligibility criteria
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- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, in person or virtual, 3 times every week for 3 months</li> <li class="seamTextUnorderedListItem">Exercise journal</li> <li class="seamTextUnorderedListItem">Fitbit</li> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2 : Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Biopsy, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Blood test, 2 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> followed 3 months later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Exercise program, 3 months (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Greater physical activity is associated with a lower risk of breast cancer.</li> <li class="seamTextUnorderedListItem">Exercise may change markers in blood and breast tissue that play a role in breast cancer development.</li> <li class="seamTextUnorderedListItem">If you are in group 1, the exercise program includes aerobic and resistance training exercise with a certified exercise trainer.</li> <li class="seamTextUnorderedListItem">If you are in group 1, a FitBit activity tracker, resistance bands, hand weights, and stationary bike will be provided to you. Hand weights will be returned at end of study.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06322888' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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NEAREST SITE: 2693 miles
Dana Farber Cancer Institute
Boston,MA
VISITS: Coincides with routine care
PHASE: NA
NCT ID: NCT05463796
Registry to Improve Cancer Prevention, Early Detection, and Treatment
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk For Cancer Scientific Title
Purpose
To collect information and samples to improve prevention, early detection, and treatment of cancer.
Who is this for?
People with stage 0 (DCIS or LCIS), stage I, stage II, or stage III breast cancer, or people with high risk of breast cancer.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be asked to complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide tissue, blood, saliva, urine, and/or stool sample(s) at routine visit</li> <li class="seamTextUnorderedListItem">Complete surveys</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">By participating in this study, your family members are also eligible to participate in this study.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05463796' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://inadvancestudy.dana-farber.org/home' target='_blank'>Dana-Farber Cancer Institute: Trial Information Page</a> </li></ul>
69
NEAREST SITE: 2693 miles
Beth Israel Deaconess Medical Center
Boston,MA
VISITS: At least 1 visit
PHASE: NA
NCT ID: NCT06011434
Online Tool to Help Women 75+ Years Old Make Mammogram Decisions
Testing a Conversation Aid on Mammography Screening for Clinicians and Women 75 and Older in Practice Scientific Title
Purpose
To develop and test an online tool to help primary care doctors discuss the pros and cons of mammograms with older women and help older women make mammogram decisions.
Who is this for?
Women 75-89 years old whose last mammogram was between 6 months and 2.5 years ago and had a normal result. You must not have a history of breast cancer. Your primary care provider must be at Beth Israel Deaconess Medical Center.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Appointment with primary care doctor</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times within 2 weeks</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The usefulness of mammograms in women older than 75 years varies according to the woman's life expectancy, risk of breast cancer, and preferences.</li> <li class="seamTextUnorderedListItem">Current guidelines recommend that primary care doctors talk to women aged 75 years and older and reach a shared decision about mammograms.</li> <li class="seamTextUnorderedListItem">The online <q>Decide Together</q> conversation tool is designed to be used by a primary care doctor and patient for shared decision making and to provide information and education on the benefits and harms of mammograms.</li> <li class="seamTextUnorderedListItem">You must have a family member willing to participate in the study. Your family member will attend the appointment with your primary care provider.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06011434' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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Studying the Relationship Between Inherited KRAS Mutations and Breast Cancer Risk
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment Scientific Title
Purpose
To study the relationship between the KRAS mutation and cancer risk.
Who is this for?
People with stage I, stage II, stage III, and stage IV (metastatic) breast cancer, or people with a family history of breast cancer. You must also have endometriosis or an autoimmune condition.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saliva sample to test for the KRAS mutation</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">An inherited KRAS genetic mutation may increase a person's risk of developing breast or other types of cancer.</li> <li class="seamTextUnorderedListItem">This study will follow participants for 10 years. </li> <li class="seamTextUnorderedListItem">The researchers will also look at the effect that different lifestyle factors have on cancer risk. </li> <li class="seamTextUnorderedListItem">Participants will be able to get their KRAS mutation test results after submitting their sample at a discounted cost ($295).</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02253251' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://miradx.com/test/kras-variant/' target='_blank'>MiraKind Research Company: KRAS-Variant</a> </li><li class='seamTextUnorderedListItem'><a href='http://mirakind.org/study-eligibility-questionnaire/' target='_blank'>Research Company: Eligibility Survey</a> </li></ul>
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Questionnaire and Medical Records Review for Breast Cancer Screening as Recommended for Women at Moderate Risk for Breast Cancer
Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer Scientific Title
Purpose
To assess breast cancer screening as recommended for women at moderately increased risk for developing breast cancer and to determine factors that promote or prevent screening.
Who is this for?
Women, age 30-75 years old, with a mutation in the genes ATM, CHEK2, BARD1, RAD51C, or RAD51D, or a lifetime breast cancer risk estimate between 20% and 40% according to the Tyrer-Cuzick V8.0B empiric risk model. You must not have breast cancer or have received a mastectomy.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaire</li> <li class="seamTextUnorderedListItem">Review of your medical records</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer risk can be estimated by genetic mutation status and models that use responses to questions about personal and family health.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07076147' target='_blank'>ClinicalTrials.gov</a> </li></ul>
72
Questionnaires to Understand Financial Impacts of Surgery and COVID-19 for Women Receiving a Mastectomy
Financial Toxicity in Patients Undergoing Breast Reconstruction: The Impact of Out of Pocket Costs, Lost Wages and Unemployment Scientific Title
Purpose
To collect information about the financial impact of breast cancer surgery and to learn if the COVID-19 pandemic affects patient costs of breast reconstruction.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women at high risk for breast cancer who are planning to receive a mastectomy and breast reconstruction at MD Anderson Cancer Center.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires, virtual, 4 times within 2 years</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">People receiving breast reconstruction after a mastectomy are at high risk for financial toxicity (harmful effects of high health care cost on well-being).</li> <li class="seamTextUnorderedListItem">The COVID-19 pandemic may affect these costs.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04169542' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/resources-support/find-financial-support-cancer/' target='_blank'>Metastatic Trial Talk: Where to Find Financial Support</a> </li></ul>
73
Empowerment and Navigation Sessions for Latina Women Ages 30+ with Breast Cancer or a Family History of Breast/Ovarian Cancer
Empowering Vulnerable and Resilient Latinas to Obtain Breast Cancer Care Scientific Title
Purpose
To compare the impact of empowerment and navigation sessions with standard of care sessions on whether Latina women decide to receive genetic testing and/or genetic counseling.
Who is this for?
Latina women ages 30+ with stage I, stage II, stage III, or stage IV (metastatic) breast cancer or with a family history of breast or ovarian cancer. You must have one social determinant of health risk factor, such as: perceived financial struggles, transportation difficulties, exposure to violence, housing challenges, social isolation/challenges. You must not have received genetic testing or genetic counseling.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, breast cancer screening, and diet and physical activity for breast cancer prevention.</li> <li class="seamTextUnorderedListItem">Standard of care sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, how to share breast cancer information, and testimonials and include role playing activities and group discussions.</li> <li class="seamTextUnorderedListItem">You can receive up to $100 for participation.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05483283' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/cancer-prevention-and-early-detection-facts-and-figures/making-the-case-for-health-equity.pdf' target='_blank'>American Cancer Society: Health Equity and Social Determinants of Health</a> </li><li class='seamTextUnorderedListItem'><a href='https://health.gov/healthypeople/priority-areas/social-determinants-health' target='_blank'>US Department of Health and Human Services: Social Determinants of Health</a> </li></ul>
74
Online Portal to Educate and Refer Racially Diverse People to Clinical Trials
Precision Clinical Trial Recruitment to Promote Cancer Health Equity Across Florida Scientific Title
Purpose
To study the tailored ALEX (Agent Leveraging Empathy for eXams) Research Portal to navigate Black and Hispanic adults with cancer and their family members through referral to cancer clinical trials.
Who is this for?
People who are Black, African American, Hispanic, and/or Latinx. People with cancer and their family members may enroll in this trial. You must live in Florida.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">ALEX (Agent Leveraging Empathy for eXams) portal</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care portal</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Racial and ethnic minorities are underrepresented in cancer clinical trials.</li> <li class="seamTextUnorderedListItem">The ALEX (Agent Leveraging Empathy for eXams) Research Portal uses culturally responsive, virtual community health educators to reach diverse populations.</li> <li class="seamTextUnorderedListItem">Clinicians can utilize the ALEX portal to refer patients to trials. Community health educators can use the portal to help provide information to patients and schedule follow-ups. Patients and family members can use the portal to access key information and make referrals.</li> <li class="seamTextUnorderedListItem">The standard of care portal provides participants with access to existing online cancer clinical trial resources in one location.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05655494' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/inside-clinical-trials/diversity-in-clinical-trials-2/' target='_blank'>Steps Toward Expanding Eligibility Criteria to Increase Diversity in Clinical Trials</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/inside-clinical-trials/diversity-in-clinical-trials/' target='_blank'>The Lack of Diversity in Clinical Trials</a> </li></ul>
75
CSC Online Survey: The Cancer Experience Registry
Cancer Experience Registry: An Online Initiative to Understand the Experiences of Those Impacted by a Cancer Diagnosis (CER) Scientific Title
Purpose
To learn more about the emotional and social experiences and needs of people affected by cancer.
Who is this for?
People diagnosed with DCIS, stage I, stage II, stage III, or metastatic (stage IV) breast cancer and people who provide care to individuals diagnosed with cancer.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> Participation in this study involves the completion of an online questionnaire. The questionnaire may be accessed at the following link: </p> <a href="http://www.cancersupportcommunity.org/MainMenu/ResearchTraining/Cancer-Experience-Registry.html" target="_blank">www.cancerexperienceregistry.org</a>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The researchers hope to use this information to improve the educational materials and the overall quality of care that cancer patients receive. </li> <li class="seamTextUnorderedListItem">This study is also enrolling people diagnosed with other types of cancer. </li> <li class="seamTextUnorderedListItem">The data collected from this study can be found <a href="https://www.cancersupportcommunity.org/RegistryIndexReport2017" target="_blank">here.</a></li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02333604' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancerexperienceregistry.org/' target='_blank'>Cancer Support Community Study Website: Cancer Experience Registry</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancersupportcommunity.org/RegistryIndexReport2017' target='_blank'>Cancer Support Community: Cancer Experience Registry Index Report 2017</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.youtube.com/watch?v=SyyUYqyNaCc' target='_blank'>Cancer Support Community YouTube Channel: What is the Cancer Experience Registry?</a> </li></ul>
76
Registry to Study the CTNNA1 Gene and Cancer Risk
CTNNA1 Familial Expansion (CAFÉ) Study Scientific Title
Purpose
To identify the cancer risks associated with inherited mutations and other changes in a gene called CTNNA1.
Who is this for?
People with mutations in the CTNNA1 gene, and people with family members who have mutations in the CTNNA1 gene.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online questionnaire about medical, genetic, and family history</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mutations and other changes in a gene called CTNNA1 may be associated with inherited cancers, including gastric cancer, breast cancer, and other cancers.</li> <li class="seamTextUnorderedListItem">Better understanding of the relationship between CTNNA1 variations and breast cancer will be important for cancer risk management of individuals with these variations and their family members.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05126290' target='_blank'>ClinicalTrials.gov</a> </li></ul>
77
Questionnaires About Pain After Mastectomy and Breast Reconstruction
Persistent Postmastectomy Pain: Defining the Burden of Disease and the Role of Surgical Reinnervation in Patients With Breast Reconstruction Scientific Title
Purpose
To study how common long-term pain is after mastectomy and breast reconstruction.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women with high risk of breast cancer who received a mastectomy and breast reconstruction surgery between 6 months and 15 years ago.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires about pain</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Pain may continue even after healing from surgery is complete.</li> <li class="seamTextUnorderedListItem">This study seeks to understand how long this pain lasts after surgery.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06627582' target='_blank'>ClinicalTrials.gov</a> </li></ul>
78
Saliva Samples and Questionnaires to Study How Genes Affect Breast Cancer Risk
The Rutgers University Genetics Coordinating Center Breast Cancer Study Scientific Title
Purpose
To study how genes impact breast cancer risk.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer, and people who have not been diagnosed with breast cancer.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide saliva (spit) sample, by mail</li> <li class="seamTextUnorderedListItem">Questionnaires, online</li> <li class="seamTextUnorderedListItem">Access to your health records (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">By participating in this study, you will receive information about your genetic risk for free.</li> <li class="seamTextUnorderedListItem">Mutations in genes called BRCA1 and BRCA2 explain only about 25% of the genetic cause of breast cancer. </li> <li class="seamTextUnorderedListItem">Researchers are trying to learn more about the genetic cause of breast cancer, which will help researchers create new treatments and improve current treatment options.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06773897' target='_blank'>ClinicalTrials.gov</a> </li></ul>
