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(Last updated: September 27, 2020)

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1

NEAREST SITE: 1625 miles
Houston Methodist Hospital Willowbrook
Houston,TX

VISITS: Number of visits unavailable, over 1 year

PHASE: II-III

NCT ID: NCT02068092

Effect of Olive Oil on Breast Density in High-Risk Women

A Pilot Study of Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention In Women At High Risk Of Breast Cancer Scientific Title

Purpose
To evaluate the effect that hydroxytyrosol has on the breast tissue of women who are at high risk for developing breast cancer.
Who is this for?
Women who are at high risk for developing breast cancer.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> All participants will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Baseline mammogram within 90 days prior to start of the study</li> <li class="seamTextUnorderedListItem">Hydroxytyrosol by mouth daily for 1 year</li> <li class="seamTextUnorderedListItem">Core needle biopsy</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Studies have shown that women with dense breast tissue are at increased risk for developing breast cancer.</li> <li class="seamTextUnorderedListItem">Laboratory studies have found that hydroxytyrosol--a major component of olive oil--is a powerful antioxidant with very low toxicity in the human body, even at high doses. </li> <li class="seamTextUnorderedListItem">Researchers think that hydroxytyrosol may reduce dense breast tissue.</li> </ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02068092' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.sciencedaily.com/releases/2014/01/140122112401.htm' target='_blank'>Science Daily: Study article</a> </li></ul>
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2

NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX

VISITS: 1 visit

PHASE: NA

NCT ID: NCT03012399

Effects of Hypnosis During Breast Cancer Surgery

Biobehavioral Effects of Hypnosis During Breast Cancer Surgery Scientific Title

Purpose
To study a relaxation method called hypnosedation.
Who is this for?
Women with DCIS or stage I breast cancer who have not yet had breast surgery.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Hypnosedation performed by a hypnotherapist, beginning right before surgery and continuing through until your surgery ends</li> <li class="seamTextUnorderedListItem">Conscious sedation during surgery</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empathetic conversation with a hypnotherapist right before surgery</li> <li class="seamTextUnorderedListItem">General anesthesia during surgery</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Using hypnosedation before and during breast cancer surgery may allow patients to avoid having general anesthesia.</li> <li class="seamTextUnorderedListItem">Hypnosedation is administered by a hypnotherapist, a mind-body specialist who uses words and images to help you relax during surgery.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03012399' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://abcnews.go.com/Health/Healthday/story?id=4508455&page=1' target='_blank'>ABC News: Hypnosis Article</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/treatment/comp_med/types/hypnosis' target='_blank'>Breastcancer.org: Hypnosis</a> </li></ul>
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3

NEAREST SITE: 1643 miles
M D Anderson Cancer Center
Houston,TX

VISITS: 10-12 visits over 8 weeks

PHASE: II

NCT ID: NCT02754752

Acupuncture for Relieving Severe Post-Mastectomy Pain

Randomized-Controlled Trial of Acupuncture for Post-Mastectomy Pain Syndrome Scientific Title

Purpose
This study is investigating whether electro-acupuncture can help reduce pain women feel after their mastectomy.
Who is this for?
Women who had a mastectomy at least 4 months ago. You must have had persistent pain in your chest area for at least 3 months and have seen your oncologist within the last 6 months.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 3 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Acupuncture on specific body points</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Up to 10 acupuncture sessions, over 4 weeks</li> <li class="seamTextUnorderedListItem">6 Questionnaires, over 8 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Acupuncture on non-specific body points</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Up to 10 acupuncture sessions, over 4 weeks</li> <li class="seamTextUnorderedListItem">6 Questionnaires, over 8 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3: Wait-List</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">No acupuncture</li> <li class="seamTextUnorderedListItem">After 4 weeks, optional participation in up to 10 acupuncture sessions, over 4 weeks</li> <li class="seamTextUnorderedListItem">6 Questionnaires, over 8 weeks</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Electro-acupuncture is a two-step process. First, hair-thin needles are put into specific points in your body. Then, a mild electrical current is applied to the needles at a level that is comfortable to you.</li> </ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02754752' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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4

NEAREST SITE: 2352 miles
University of Rochester
Rochester,NY

VISITS: 1 visit a week, for 2 months

PHASE: NA

NCT ID: NCT03045289

Plant-Based Nutrition for Women with Metastatic Breast Cancer

Whole-Food, Plant-Based Nutrition Among Women With Metastatic Breast Cancer: A Pilot Study of Recruitment, Retention, and Preliminary Changes in Biomarkers and Symptoms. Scientific Title

Purpose
To explore the feasibility of conducting a study looking at the effect of a plant-based diet in women with stable metastatic breast cancer.
Who is this for?
Women with stable stage IV metastatic breast cancer who have had at least one imaging test (CT scan, bone scan, or PET/CT) within the last 6 months. You must currently be receiving systemic anti-cancer therapy.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will randomly be assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">3 meals daily, delivered to your home, for 2 months</li> <li class="seamTextUnorderedListItem">1 office visit, weekly</li> <li class="seamTextUnorderedListItem">Multivitamin, daily</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Maintain current food intake</li> <li class="seamTextUnorderedListItem">Multivitamin, daily</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study will also provide preliminary data on the effect of plant-based nutrition on cancer prognosis and overall health.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03045289' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/research-news/20070321b' target='_blank'>Breastcancer.org: Plant-Based Diet May Decrease Risk</a> </li><li class='seamTextUnorderedListItem'><a href='http://cancer.ucsf.edu/_docs/crc/nutrition_breast.pdf' target='_blank'>UCSF Cancer Center: Nutrition & Breast Cancer (pdf file)</a> </li></ul>
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5

NEAREST SITE: 2434 miles
Georgetown University
Washington,DC

VISITS: 1 visit

PHASE: NA

NCT ID: NCT03091647

Acupressure for Chinese Immigrant Breast Cancer Survivors in Los Angeles

Acupressure Intervention to Improve Fatigue and Physical Functioning of Chinese Immigrant Breast Cancer Survivors Scientific Title

Purpose
To see whether using a Chinese-language video to teach patients how to self-administer acupressure helps improve cancer-related fatigue and quality of life better than the current standard of care.
Who is this for?
First-generation immigrants who speaks Chinese (Mandarin or Cantonese) and live in or near Los Angeles, California. You must have been treated for DCIS or Stage I, II, or III breast cancer within the last 1 to 5 years and have moderate to severe levels of fatigue.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Acupressure</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Learn acupressure practice from an instructional video in Chinese </li> <li class="seamTextUnorderedListItem">Self-administer acupressure and record practice in a log, daily, for 2 months</li> <li class="seamTextUnorderedListItem">2 phone interviews, at baseline and at follow-up </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care support </li> <li class="seamTextUnorderedListItem">Record fatigue and functioning levels in a log, daily, for 2 months </li> <li class="seamTextUnorderedListItem">2 phone interviews, at baseline and at follow-up</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is investigating whether using a Chinese-language video to teach patients how to self-administer acupressure helps improve cancer-related fatigue and quality of life better than the current standard of care.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03091647' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ww5.komen.org/BreastCancer/Acupressure.html' target='_blank'>Susan G. Komen: Acupressure</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/research-news/self-acupressure-eases-anxiety-pain-depression' target='_blank'>Breastcancer.org: Self-administered Acupressure</a> </li></ul>
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6

NEAREST SITE: 2693 miles
Massachusetts General Hospital
Boston,MA

VISITS: Number of visits unavailable, before surgery

PHASE: I

NCT ID: NCT03596073

Topical Ointment Calcipotriene Before Surgery to Stimulate Immune Cells

A Pilot Trial of Topical Calcipotriene Treatment for Breast Cancer Immunoprevention Scientific Title

Purpose
To see the effect that a topical ointment called calcipotriene has on the tumor's microenvironment.
Who is this for?
People who are 45 or older, scheduled to have breast cancer surgery, and not receiving chemotherapy before surgery.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Topical calcipotriene ointment, 2 times per day, for the period between biopsy and surgery</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Topical vaseline, 2 times per day, for the period between core biopsy and surgery</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Calcipotriene is a man-made form of vitamin D.</li> <li class="seamTextUnorderedListItem">It is approved by the FDA to treat psoriasis. Its use in breast cancer is experimental. </li> <li class="seamTextUnorderedListItem">Giving the treatment before surgery allows researchers to look at how it affects the tumor's microenvironment.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03596073' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.webmd.com/drugs/2/drug-1506/calcipotriene-topical/details' target='_blank'>WebMD: Calcipotriene</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pubmed/1672178' target='_blank'>Pubmed: Topical calcipotriol treatment in advanced breast cancer</a> </li></ul>
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