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NEAREST SITE: 2604 miles
Stony Brook University
Stony Brook,NY

VISITS: Weekly visits, ongoing

PHASE: II

NCT ID: NCT05159778

Imprime PGG and Pembrolizumab For HR+, HER2- Metastatic Breast Cancer

A Multicenter, Open-label, Phase 2 Study of Imprime PGG and Pembrolizumab in Patients With Metastatic Breast Cancer (mBCA) Who Have Progressed Through Prior Hormonal Therapy Scientific Title

Purpose
To study the anti-cancer activity of the experimental immunotherapy, Imprime PGG, given with pembrolizumab (Keytruda®).
Who is this for?
People with metastatic (stage IV) hormone-positive (ER+ and/or PR+), HER2 negative breast cancer who havereceived treatment with hormone therapy with at least one CDK4/6 inhibitor, and no more than one chemotherapy treatment.    Full eligibility criteria
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  • How can I learn more?
  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Imprime PGG, by IV, weekly</li> <li class="seamTextUnorderedListItem">Pembrolizumab (Keytruda®), by IV, every 3 weeks</li> <li class="seamTextUnorderedListItem">2-3 biopsies</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Imprime PGG is an experimental immunotherapy drug.</li> <li class="seamTextUnorderedListItem">Pembrolizumab (Keytruda®) is a type of immunotherapy called a PD-1 inhibitor. Blocking PD-1 may allow the body's immune system to detect and fight cancer cells.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05159778' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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