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(Last updated: October 14, 2021)

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NEAREST SITE: 3 miles
UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco,CA

VISITS: Number of visits unavailable

PHASE: I

NCT ID: NCT04526106

Targeted Therapy RLY-4008 for Advanced Breast Cancer with a FGFR2 Mutation, Fusion, or Amplification

A First-in-human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With Intrahepatic Cholangiocarcinoma (ICC) and Other Advanced Solid Tumors Scientific Title

Purpose
To study the best dose, safety, side effects, and ant-cancer activity of the experimental targeted therapy RLY-4008.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer that tests positive for a FGFR2 mutation, fusion, or amplification.    Full eligibility criteria
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  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">RLY-4008, by mouth</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for treatment schedule</i></p>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">RLY-4008 is an experimental FGFR2 inhibitor. Researchers think inhibiting (blocking) the FGFR pathway may stop or slow the growth of certain tumors.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li> <li class="seamTextUnorderedListItem">Targets or mutations: FGFR2</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04526106' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://relaytx.com/pipeline/' target='_blank'>Relay Therapeutics Drug Information Page: RLY-4008</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071019/' target='_blank'>Journal Article: Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer</a> </li></ul>
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