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(Last updated: November 29, 2020)

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1

NEAREST SITE: 1643 miles
M.D. Anderson Cancer Center
Houston,TX

VISITS: 1 visit every 3 weeks, ongoing

PHASE: I

NCT ID: NCT04450732

Anti-HER2 Targeted Therapy GQ1001 in Advanced HER2 Positive Breast Cancer

A Phase 1, First-In-Human, Multicenter, Open-Label, Study of GQ1001, a HER2 Targeted Antibody-Drug Conjugate, Administered Intravenously, in Adult Patients With HER2-Positive Advanced Solid Tumors Scientific Title

Purpose
To study the best dose of GQ1001--an experimental antibody-drug conjugate (ADC).
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) HER2 positive (HER2+) breast cancer who have no standard treatment options available.    Full eligibility criteria
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  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">GQ1001, by IV, every 3 weeks, ongoing</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Antibody-drug conjugates are cancer therapies that combine an antibody that targets cancer cells with a drug that can kill cancer cells. </li> <li class="seamTextUnorderedListItem">Because the antibody only targets cancer cells, the drug does not kill normal cells, making it less likely to cause side effects.</li> <li class="seamTextUnorderedListItem">GQ1001 targets the HER2 protein on cancer cells. </li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of HER2+ cancer.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04450732' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.crconc.com/basic/press/press_20200713' target='_blank'>Press Release: GeneQuantum Healthcare Announces First Patient Dosed in Phase I Clinical Trial of GQ1001</a> </li></ul>
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