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NEAREST SITE: 538 miles
Providence Cancer Institute

VISITS: Number of visits unavailable


NCT ID: NCT03602079

A166 for HER2 Positive and HER2 Low Expression Advanced Breast Cancer

A Phase I-II, FIH Study of A166 in Locally Advanced/Metastatic Solid Tumors Expressing Human Epidermal Growth Factor Receptor 2 (HER2) or Are HER2 Amplified That Did Not Respond or Stopped Responding to Approved Therapies Scientific Title

To evaluate the safety and effects (good and bad) of the experimental therapy A166.
Who is this for?
Women and men with HER2 positive or low HER2 expression advanced (some stage III) or metastatic (stage IV) breast cancer that has not responded to standard therapies    Full eligibility criteria
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  • <p class="seamTextPara"> You will receive: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A166, by IV </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for treatment schedule</i></p>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A166 combines chemotherapy with a HER2 targeted therapy, allowing it to deliver the chemotherapy directly to the cancer cells. </li> <li class="seamTextUnorderedListItem">Your tumor is HER2-low-expressing if the results of your immunohistochemical (IHC) test for HER2 were 1 (negative) or 2 (borderline).</li> <li class="seamTextUnorderedListItem">This study is also enrolling patients with other types of advanced cancer.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03602079' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.yicaiglobal.com/news/kelun-pharmaceutical%E2%80%99s-anti-cancer-drug-obtains-clinical-trial-permission-fda' target='_blank'>Klus Pharma: A166</a> </li></ul>
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