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In response to COVID-19, some breast cancer trials have temporarily stopped enrolling new patients. Use the contact information in our trial listings to call or email the research site for information about a trial's status.

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(Last updated: July 01, 2022)

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Treatment

Brain Mets

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Targeted Therapy: All

Targeted Therapy: Anti-HER2 Therapy

Targeted Therapy: CDK Inhibitors

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AKT

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CHEK2 or CHEK1

ESR1

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HLA

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NTRK

PALB2

PIK3CA or PI3K

PTEN

RAD51

RAF (including BRAF)

RAS (KRAS or NRAS)

RB

ROS1

TP53

Click here to view online studies and trials that do not require site visits

1

NEAREST SITE: 350 miles
Herald Cancer Association
Los Angeles,CA

VISITS: Number of visits unavailable

PHASE: NA

NCT ID: NCT02946697

A Social Support Program Developed for Chinese-Speaking Breast Cancer Survivors

A Culturally Sensitive Social Support Intervention Scientific Title

Purpose
To look at whether a social support program can help improve quality of life.
Who is this for?
Women who are Chinese speakers (Mandarin or Cantonese) who have been treated for DCIS or stage I, stage II, or stage III breast cancer within the last 3 years. You must also live in or near Los Angeles, California.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Culturally-Based Social Support Program</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education and peer-support program, 7 weeks</li> <li class="seamTextUnorderedListItem">Receive weekly phone calls from peer-mentor</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Wait List</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care (no intervention)</li> <li class="seamTextUnorderedListItem">Option to participate in the education and peer-support program after 7 weeks</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The program will address topics including treatment-related side effects, symptoms of cancer recurrence, physical therapy and other complementary treatments, stress, depression and other emotional problems, communicating with family members, and body image. </li> <li class="seamTextUnorderedListItem">Each study participant will have the opportunity to establish a relationship with a peer-mentor who is also a Chinese-speaking breast cancer survivor.</li> </ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02946697' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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2

No Travel Required

VISITS: Weekly phone sessions, for 6 weeks

PHASE: II

NCT ID: NCT03998618

Telephone Support to Reduce Fatigue in Women With Metastatic Breast Cancer

Telephone Support for Metastatic Breast Cancer Patients Scientific Title

Purpose
To evaluate whether a telephone-based psychotherapy program can reduce fatigue and improve activity level, mood, and cognition.
Who is this for?
Women with metastatic (stage IV) breast cancer being treated at the Indiana University (IU) Simon Cancer Center, Eskenazi Health, IU Health North, IU Health Bloomington, IU Health Ball Memorial, Franciscan Health, or St. Vincent Health.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1:</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Acceptance and Commitment Therapy: 50-minute phone sessions, weekly, for 6 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2:</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education/Support: 50-minute phone sessions, weekly, for 6 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Follow-up</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">30-minute phone assessments at 2 weeks, 3 months, and 6 months after study activities</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The type of psychotherapy being studied is called Acceptance and Commitment Therapy (ACT). </li> <li class="seamTextUnorderedListItem">It teaches mindfulness exercises as well as ways to identify and engage in activities consistent with your personal values.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03998618' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pubmed/29327085' target='_blank'>Pubmed Abstract: Acceptance and commitment therapy for symptom interference in metastatic breast cancer patients</a> </li></ul>
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3

No Travel Required

VISITS: Online surveys and journaling, for 13 months

PHASE: NA

NCT ID: NCT04651452

Guided Journaling to Support Women with Stage I-III Breast Cancer Taking an Aromatase Inhibitor (A Fully Remote Trial)

A Value Affirmation Intervention for Physical Symptoms and Medication Adherence in Breast Cancer Patients Taking Aromatase Inhibitors Scientific Title

Purpose
To study and compare the effects two different writing programs have on taking aromatase inhibitors (AI) as prescribed, AI side effects, and stress.
Who is this for?
Women with stage I, stage II, or stage III breast cancer intending to start taking a type of anti-estrogen therapy called an aromatase inhibitor. Women may also enroll if they are within 4 weeks of starting an aromatase inhibitor.    Full eligibility criteria
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Values</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">6 writing assignments about values, once a month, for 6 months</li> <li class="seamTextUnorderedListItem">Electronic pill bottle to record when you take your medication</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Reflection</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">6 writing assignments on your reflections, once a month, for 6 months</li> <li class="seamTextUnorderedListItem">Electronic pill bottle to record when you take your medication</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Aromatase inhibitors are a type of anti-estrogen therapy commonly used for hormone-positive breast cancer. The approved aromatase inhibitors are anastrozole (Arimidex®), letrozole (Femara®), and exemestane (Aromasin®). </li> <li class="seamTextUnorderedListItem">Some women stop taking aromatase inhibitors because of side effects. </li> <li class="seamTextUnorderedListItem">This trial is studying whether guided journaling can help women continue to take their aromatase inhibitors.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04651452' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal/aromatase_inhibitors' target='_blank'>Breastcancer.org: Aromatase Inhibitors</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.healthandhumanperformancelab.com/breastcancerstudy' target='_blank'>The Health and Human Performance Lab Trial Website</a> </li></ul>
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4

No Travel Required

VISITS: No visits required

PHASE: NA

NCT ID: NCT03452774

Using Artificial Intelligence to Match Patients to Clinical Trials (SYNERGY-AI)

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry Scientific Title

Purpose
To study if a computer that has been taught how to match people to clinical trials (artificial intelligence) can help increase enrollment in clinical trials.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer who have already decided to enroll in a clinical trial.    Full eligibility criteria
Contact research site
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Contact Research Sites

  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will receive: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A clinical trial matching report based on your medical records that you can review with your doctor.</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial will use artificial intelligence and virtual tumor boards to help match people to clinical trials.</li> <li class="seamTextUnorderedListItem">The researchers will also create a registry to study the medical and financial effects of this program. </li> <li class="seamTextUnorderedListItem">This is an international trial that is also enrolling people with other types of cancer.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03452774' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://massivebio.com/' target='_blank'>Massive Bio Study Information Page</a> </li></ul>
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