Browse Trials
In response to COVID-19, some breast cancer trials have temporarily stopped enrolling new patients. Use the contact information in our trial listings to call or email the research site for information about a trial's status.
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(Last updated: April 15, 2021)
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Treatment
BRCA1/2 (inherited)
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Surgery: Reconstruction
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Targeted Therapy: Anti-HER2 Therapy
Targeted Therapy: CDK Inhibitors
Targeted Therapy: PARP Inhibitors
Targeted Therapy: Tumor Mutations
Targeted Therapy: Other Targeted Therapy
Vaccines and Immunotherapy
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AKT
ALK
AR
BARD1
BRCA1/2 (tumor)
BRIP1
CD205
CD70
CHEK2 or CHEK1
ESR1
FGFR
HER2/ERBB2
HLA
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NTRK
PALB2
PIK3CA or PI3K
PTEN
RAD51
RAF (including BRAF)
RAS (KRAS or NRAS)
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Click here to view online studies and trials that do not require site visits
1
NEAREST SITE: 350 miles
Herald Cancer Association
Los Angeles,CA
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT02946697
A Social Support Program Developed for Chinese-Speaking Breast Cancer Survivors
A Culturally Sensitive Social Support Intervention Scientific Title
Purpose
To look at whether a social support program can help improve quality of life.
Who is this for?
Women who are Chinese speakers (Mandarin or Cantonese) who have been treated for DCIS or stage I, stage II, or stage III breast cancer within the last 3 years. You must also live in or near Los Angeles, California.
Full eligibility criteria
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- What's involved?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Culturally-Based Social Support Program</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education and peer-support program, 7 weeks</li> <li class="seamTextUnorderedListItem">Receive weekly phone calls from peer-mentor</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Wait List</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care (no intervention)</li> <li class="seamTextUnorderedListItem">Option to participate in the education and peer-support program after 7 weeks</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The program will address topics including treatment-related side effects, symptoms of cancer recurrence, physical therapy and other complementary treatments, stress, depression and other emotional problems, communicating with family members, and body image. </li> <li class="seamTextUnorderedListItem">Each study participant will have the opportunity to establish a relationship with a peer-mentor who is also a Chinese-speaking breast cancer survivor.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02946697' target='_blank'>ClinicalTrials.gov</a> </li></ul>
2
NEAREST SITE: 1643 miles
University of Texas MD Anderson Cancer Center
Houston,TX
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT03429907
A Stress-Reduction Program for Women Getting Chemo Before Breast Cancer Surgery
An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer: A Randomized Pilot Study Scientific Title
Purpose
To see whether patients who use a mind-body stress-reduction app for two weeks before starting neoadjuvant chemotherapy have lower stress, better mood, and fewer physical symptoms during treatment than patients who do not take part in this program.
Who is this for?
Women with stage I, stage II, or stage III breast cancer who will have chemotherapy before surgery (neoadjuvant treatment) at MD Anderson Cancer Center in Texas.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mind-body exercises using an app, daily for 2 weeks before starting chemotherapy</li> <li class="seamTextUnorderedListItem">4 questionnaires, before, during and after chemotherapy</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">4 questionnaires, before, during and after chemotherapy</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The exercises are presented on an online application (<q>app</q>) on your personal electronic device.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03429907' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/tips/exercise/treatment/chemo_targeted' target='_blank'>Breastcancer.org: Exercise During and After Chemotherapy or Targeted Therapies</a> </li></ul>
3
NEAREST SITE: 2139 miles
Emory University Hospital
Atlanta,GA
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT02803593
Computer and Internet-Based Support Program for Asian-American Breast Cancer Survivors
To Enhance Breast Cancer Survivorship of Asian Americans Scientific Title
Purpose
To evaluate whether an internet and computer-based information and coaching/support program designed specifically for Asian-American breast cancer survivors improves quality of life
Who is this for?
Women who have been diagnosed with breast cancer within the past 5 years and identify as Chinese, Korean, or Japanese. You must also have access to the internet through a computer, smartphone or tablet.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Support Care Needs survey at baseline</li> <li class="seamTextUnorderedListItem">Receive culturally tailored internet and computer-based information and coaching/support in one of four languages (English, Mandarin Chinese, Korean, and Japanese)</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Support Care Needs survey at baseline</li> <li class="seamTextUnorderedListItem">Standard support provided by American Cancer Society</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The program is provided in English, Mandarin Chinese, Korean, and Japanese.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02803593' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.dukecancerinstitute.org/news/cancer-survivorship-asian-americans' target='_blank'>Duke Cancer Institute: Cancer Survivorship of Asian Americans</a> </li></ul>
4
NEAREST SITE: 2384 miles
Duke University Medical Center
Durham,NC
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT02707471
Treatment Adherence for Stage I-III Breast Cancer Patients Taking a Hormone Therapy Drug
Improving Well-Being for Breast Cancer Patients Taking Adjuvant Endocrine Therapy Scientific Title
Purpose
To determine which type of phone counseling session helps women continue to take their anti-estrogen drugs daily.
Who is this for?
Women with stage I, stage II, and stage III hormone receptor positive (ER+ and/or PR+) breast cancer. You must also be planning on taking an anti-estrogen drug after surgery.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups and undergo the following over 1.5 years: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Intervention</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">10 phone counseling sessions with a nurse </li> <li class="seamTextUnorderedListItem">Interactive voice messaging tailored to your medication-taking behavior </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">10 phone counseling sessions on general health education with a nurse</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will receive a smart medication bottle that records the time you take your drug and sends this information to the research team.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02707471' target='_blank'>ClinicalTrials.gov</a> </li></ul>
5
NEAREST SITE: 2693 miles
Dana Farber Cancer Institute
Boston,MA
VISITS: 3 visits
PHASE: NA
NCT ID: NCT02823262
Decision Aid for Women Age 70 and Older Diagnosed with ER+, HER2- Stage I-II Breast Cancer
A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older Scientific Title
Purpose
To evaluate a breast cancer treatment Decision Aid created specifically for newly diagnosed older women.
Who is this for?
Women 70 or older who have been diagnosed with estrogen receptor positive (ER+), HER2 negative breast cancer. Your tumor must be either stage I or stage II.
Full eligibility criteria
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- What's involved?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Decision Aid</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Initial surgical consultation</li> <li class="seamTextUnorderedListItem">Treatment decision assistance provided by the Decision Aid</li> <li class="seamTextUnorderedListItem">Assessments, at 1 week and 5 months after surgical consultation</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Initial surgical consultation</li> <li class="seamTextUnorderedListItem">Usual care assistance when making treatment decisions</li> <li class="seamTextUnorderedListItem">Assessments, at 1 week and 5 months after surgical consultation</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">There are two phases to this study. </li> <li class="seamTextUnorderedListItem">In phase I, the researchers will collect feedback about the Decision Aid from breast cancer patients age 70 and over who were treated at least six months ago and their family members and clinicians. </li> <li class="seamTextUnorderedListItem">The researchers will use this feedback to improve the Decision Aid. </li> <li class="seamTextUnorderedListItem">In Phase II, the researchers will see if the revised Decision Aid helps women age 70 and older who have been diagnosed with breast cancer make treatment decisions.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02823262' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://clinicaltrials.gov/ct2/show/NCT02823262?term=NCT02823262&rank=1' target='_blank'>The Decision Aid</a> </li></ul>
6
Telephone Support to Reduce Fatigue in Women With Metastatic Breast Cancer
Telephone Support for Metastatic Breast Cancer Patients Scientific Title
Purpose
To evaluate whether a telephone-based psychotherapy program can reduce fatigue and improve activity level, mood, and cognition.
Who is this for?
Women with metastatic (stage IV) breast cancer being treated at the Indiana University (IU) Simon Cancer Center, Eskenazi Health, IU Health North, IU Health Bloomington, IU Health Ball Memorial, Franciscan Health, or St. Vincent Health.
Full eligibility criteria
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- What's involved?
- What's being studied?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1:</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Acceptance and Commitment Therapy: 50-minute phone sessions, weekly, for 6 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2:</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education/Support: 50-minute phone sessions, weekly, for 6 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Follow-up</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">30-minute phone assessments at 2 weeks, 3 months, and 6 months after study activities</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The type of psychotherapy being studied is called Acceptance and Commitment Therapy (ACT). </li> <li class="seamTextUnorderedListItem">It teaches mindfulness exercises as well as ways to identify and engage in activities consistent with your personal values.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03998618' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pubmed/29327085' target='_blank'>Pubmed Abstract: Acceptance and commitment therapy for symptom interference in metastatic breast cancer patients</a> </li></ul>
7
Using Artificial Intelligence to Match Patients to Clinical Trials (SYNERGY-AI)
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry Scientific Title
Purpose
To study if a computer that has been taught how to match people to clinical trials (artificial intelligence) can help increase enrollment in clinical trials.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer who have already decided to enroll in a clinical trial.
Full eligibility criteria
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<p class="seamTextPara"> You will receive: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A clinical trial matching report based on your medical records that you can review with your doctor.</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial will use artificial intelligence and virtual tumor boards to help match people to clinical trials.</li> <li class="seamTextUnorderedListItem">The researchers will also create a registry to study the medical and financial effects of this program. </li> <li class="seamTextUnorderedListItem">This is an international trial that is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03452774' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://massivebio.com/' target='_blank'>Massive Bio Study Information Page</a> </li></ul>
