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In response to COVID-19, some breast cancer trials have temporarily stopped enrolling new patients. Use the contact information in our trial listings to call or email the research site for information about a trial's status.

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(Last updated: August 03, 2020)

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1

NEAREST SITE: 2 miles
Zuckerberg San Francisco General Hospital
San Francisco,CA

VISITS: 3 or 5 visits over 5 years

PHASE: III

NCT ID: NCT03233191

Digital Tomosynthesis Mammography for Breast Cancer Screening

Tomosynthesis Mammographic Imaging Screening Trial (TMIST) Scientific Title

Purpose
To study whether digital tomosynthesis (3D) mammography or digital (2D) mammography is better at finding early-stage tumors and improving breast cancer survival.
Who is this for?
Women who have never been diagnosed with DCIS or breast cancer. You must not have had a screening mammogram within the last 11 months.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard digital (2D) mammogram, once a year for 5 years if pre-menopausal; every other year for 5 years if post-menopausal</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Digital tomosynthesis (3D) mammogram, once a year for 5 years if pre-menopausal; every other year for 5 years if post-menopausal</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Digital tomosynthesis (3D) mammography is approved by the FDA but is not considered the standard of care for breast cancer screening. </li> <li class="seamTextUnorderedListItem">Digital (2D) mammography is the standard of care for breast cancer screening.</li> </ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03233191' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/symptoms/testing/types/dig_tomosynth' target='_blank'>Breastcancer.org: Digital Tomosynthesis</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.hopkinsmedicine.org/breast_center/treatments_services/breast_cancer_screening/digital_mammography/index.html' target='_blank'>Johns Hopkins Medicine: Digital Mammography</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/news-events/cancer-currents-blog/2017/tmist-breast-cancer-screening' target='_blank'>NCI: TMIST Trial Aims to Provide Clarity on Breast Cancer Screening Approaches</a> </li></ul>
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2

NEAREST SITE: 3 miles
University of California San Francisco
San Francisco,CA

VISITS: Online surveys

PHASE: NA

NCT ID: NCT02620852

WISDOM Study: Women Informed to Screen Depending on Measures of Risk

Enabling a Paradigm Shift: A Preference-Tolerant RCT of Personalized vs. Annual Screening for Breast Cancer Scientific Title

Purpose
To compare risk-based screening to annual screening for measuring breast cancer risk and detecting breast cancer.
Who is this for?
Women between the ages of 40 and 70 who have never been diagnosed with breast cancer or ductal carcinoma in situ (DCIS). You must also be able to receive breast screening at an Athena site: University of California (San Francisco, San Diego, Davis, Los Angeles, and Irvine), or Sanford Health in South Dakota.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Risk-Based Screening</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening advice based on comprehensive risk assessment </li> <li class="seamTextUnorderedListItem">Saliva sample genetic testing </li> <li class="seamTextUnorderedListItem">Health questionnaires </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard Annual Screening</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Screening advice based on basic risk assessment </li> <li class="seamTextUnorderedListItem">Health questionnaires</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized risk-based screening will take multiple risk factors into consideration, including genetic markers, to determine how often you should have a mammogram.</li> <li class="seamTextUnorderedListItem">This study will help researchers learn if risk-based screening, which helps women learn more about their personal breast cancer risk, is less stressful and as successful at detecting breast cancer through annual screening. </li> <li class="seamTextUnorderedListItem">This study is available in English and Spanish.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02620852' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.athenacarenetwork.org/wisdom-study' target='_blank'>WISDOM Study</a> </li></ul>
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3

NEAREST SITE: 2438 miles
Walter Reed Army Medical Center
Washington,DC

VISITS: 1 visit

PHASE: NA

NCT ID: NCT01322750

A Circulating Tumor Cell Test To Screen For Breast Cancer At Walter Reed National Military Medical Center

Circulating Tumor Cells (CTCs): A Potential Screening Test for Clinically Undetectable Breast Carcinoma Scientific Title

Purpose
To study if a blood test for circulating tumor cells (CTCs) can reliably find breast cancer before your cancer has become clinically detectable (seen on a mammogram, ultrasound, or other imaging).
Who is this for?
People without breast cancer and people with DCIS, stage I, stage II, or stage III breast cancer who are having a diagnostic or therapeutic procedure (biopsy, lumpectomy, mastectomy) done at Walter Reed National Military Medical Center.    Full eligibility criteria
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  • What's involved?
  • What's being studied?
  • How can I learn more?
  • <p class="seamTextPara"> You will have your blood drawn</p>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Scientists are researching new techniques to screen for breast cancer.</li> <li class="seamTextUnorderedListItem">Breast cancer cells can leave the tumor and move through the blood stream before the tumor is clinically detectable.</li> <li class="seamTextUnorderedListItem">Circulating tumor cell tests look for these traveling cancer cells and may provide a simple, reliable, and cost-effective form of breast cancer screening.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT01322750' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.cbcp-research.org' target='_blank'>Walter Reed National Military Medical Center: Clinical Breast Care Project</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/symptoms/testing/types/blood_marker.jsp' target='_blank'>Breastcancer.org: Blood Marker Tests</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.gov/types/breast/patient/breast-screening-pdq' target='_blank'>NCI: Breast Cancer Screening</a> </li></ul>
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