Browse Trials
In response to COVID-19, some breast cancer trials have temporarily stopped enrolling new patients. Use the contact information in our trial listings to call or email the research site for information about a trial's status.
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Currently viewing trials
(Last updated: April 15, 2021)
BRCA1/2 (inherited)
Chemotherapy
Hormone Therapy
Radiation Oncology
Surgery
Surgery: Reconstruction
Targeted Therapy: All
Targeted Therapy: Anti-HER2 Therapy
Targeted Therapy: CDK Inhibitors
Targeted Therapy: PARP Inhibitors
Targeted Therapy: Tumor Mutations
Targeted Therapy: Other Targeted Therapy
Vaccines and Immunotherapy
Other Treatment
Activities
Complementary and Alternative Medicine
Decision Support
Diagnosing Breast Cancer
Genetics/Family History
Having Children
Lymphedema
Managing Side Effects
No Travel Required
Predicting Response to Treatment
Preventing Breast Cancer
Preventing Recurrence
Screening
Support/Education
Surveys/Interviews/Registries
AKT
ALK
AR
BARD1
BRCA1/2 (tumor)
BRIP1
CD205
CD70
CHEK2 or CHEK1
ESR1
FGFR
HER2/ERBB2
HLA
MET or C-Met
NTRK
PALB2
PIK3CA or PI3K
PTEN
RAD51
RAF (including BRAF)
RAS (KRAS or NRAS)
RB
ROS1
TP53
NEAREST SITE: 347 miles
City of Hope South Pasadena
South Pasadena,CA
VISITS: Number of visits unavailable
PHASE: III
NCT ID: NCT01905046
Metformin to Reduce Breast Cancer Risk in Women with Increased Risk of Developing Breast Cancer
Testing for Atypia in Random Periareolar Fine Needle Aspiration (RPFNA) Cytology After 12 Months Metformin (1,1-Dimethylbiguanide Hydrochloride) Chemoprevention Versus Placebo Control in Premenopausal Women Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> All participants will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Metformin, by mouth, daily for 2 years</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo, by mouth, daily for 1 year (may crossover to Group 1 for 1 year)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Women who have been diagnosed with atypical hyperplasia, DCIS or LCIS are at increased risk of developing breast cancer. </li> <li class="seamTextUnorderedListItem">Researchers are trying to find drugs (chemoprevention) that can reduce this risk. </li> <li class="seamTextUnorderedListItem">Findings from previous studies suggest that metformin, a drug used to treat diabetes, can reduce breast cancer risk in high-risk women.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT01905046' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.cancer.gov/about-cancer/causes-prevention/research/metformin' target='_blank'>NCI: Metformin Help Prevent Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.cancer.net/navigating-cancer-care/prevention-and-healthy-living/chemoprevention' target='_blank'>Cancer.net: Chemoprevention</a> </li></ul>
NEAREST SITE: 1625 miles
Houston Methodist Hospital Willowbrook
Houston,TX
VISITS: Number of visits unavailable, over 1 year
PHASE: II-III
NCT ID: NCT02068092
Effect of Olive Oil on Breast Density in High-Risk Women
A Pilot Study of Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention In Women At High Risk Of Breast Cancer Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> All participants will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Baseline mammogram within 90 days prior to start of the study</li> <li class="seamTextUnorderedListItem">Hydroxytyrosol by mouth daily for 1 year</li> <li class="seamTextUnorderedListItem">Core needle biopsy</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Studies have shown that women with dense breast tissue are at increased risk for developing breast cancer.</li> <li class="seamTextUnorderedListItem">Laboratory studies have found that hydroxytyrosol--a major component of olive oil--is a powerful antioxidant with very low toxicity in the human body, even at high doses. </li> <li class="seamTextUnorderedListItem">Researchers think that hydroxytyrosol may reduce dense breast tissue.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02068092' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.sciencedaily.com/releases/2014/01/140122112401.htm' target='_blank'>Science Daily: Study article</a> </li></ul>
NEAREST SITE: 2432 miles
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda,MD
VISITS: Number of visits unavailable
PHASE: NA
NCT ID: NCT00028340
Using Breast Duct Cells to Assess Cancer Risk
Characterization of High Risk Breast Duct Epithelium by Cytology, Breast Duct Endoscopy, and cDNA Gene Expression Profile Scientific Title
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> All participants will receive the following procedures: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Ductal lavage to collect milk duct cells</li> <li class="seamTextUnorderedListItem">Ductal endoscopy to observe the structure of the duct</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Most breast cancers begin in the cells that line the milk ducts in the breast. </li> <li class="seamTextUnorderedListItem">Previous studies have identified certain changes in the ductal cells and breast tissue that are associated with an increased risk of developing breast cancer. </li> <li class="seamTextUnorderedListItem">Ductal lavage and ductal endoscopy are techniques that allow researchers to study the cells and fluid that line the breast duct.</li> </ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT00028340' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='http://www.breastcancer.org/symptoms/testing/types/ductal' target='_blank'>breastcancer.org: Ductal Lavage</a> </li></ul>
