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Find Breast Cancer Clinical Trials That Are Right For You
The clinical trials listed below are open in the U.S. for people with DCIS (stage 0), stage 1, stage 2, stage 3, or stage 4 (metastatic)
breast cancer. Clinical trials are available for people who are newly diagnosed with breast cancer, currently in treatment, experiencing
breast cancer recurrence, living with metastatic disease, as well as breast cancer survivors who have completed treatment.
Use the search box and filters to find a trial that’s right for you.
Currently viewing trials
(Last updated: April 29, 2025)
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Treatment
Brain Mets
BRCA1/2 (inherited)
Chemotherapy
Hormone Therapy
Leptomeningeal Disease
Radiation Oncology
Surgery
Surgery: Reconstruction
Targeted Therapy: All
Targeted Therapy: ADC
Targeted Therapy: Anti-HER2 Therapy
Targeted Therapy: CDK Inhibitors
Targeted Therapy: PARP Inhibitors
Targeted Therapy: Tumor Mutations
Targeted Therapy: Other Targeted Therapy
Vaccines and Immunotherapy
Other Treatment
Non-Treatment
Activities
Complementary and Integrative Medicine
Decision Support
Diagnosing Breast Cancer
Genetics/Family History
Having Children
Healthy/High Risk
Imaging
Lymphedema
Managing Side Effects
No Travel Required
Predicting Response to Treatment
Preventing Breast Cancer
Preventing Recurrence
Support/Education
Surveys/Interviews/Registries
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AKT
ALK
AR
BARD1
BRCA1/2 (tumor)
BRIP1
CD205
CD70
CHEK2 or CHEK1
dMMR/MSI-H
ESR1
FGFR
HER2/ERBB2
HLA
MET or C-Met
NTRK
PALB2
PIK3CA or PI3K
PTEN
RAD51
RAF (including BRAF)
RAS (KRAS or NRAS)
RB
ROS1
TP53
Click here to view online studies and trials that do not require site visits
1
Telephone and Online Support for Women with Stage I-III, HR+, HER2- Breast Cancer Taking Anti-Estrogen Therapy
Optimizing Endocrine Therapy Through Motivational Interviewing and Text Interventions Scientific Title
Purpose
To study if different types of telephone and online education can help women take their anti-estrogen therapy.
Who is this for?
Women with stage I, stage II or stage III hormone positive (ER+ and/or PR+), HER2 negative (HER2-) breast cancer who have started taking anti-estrogen therapy within the last 6 months or intend to start taking it within the next 6 weeks.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 4 groups and receive the following: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online education about anti-estrogen therapy, 1 time</li> <li class="seamTextUnorderedListItem">Text message reminders to take anti-estrogen therapy, daily, for 9 months</li> <li class="seamTextUnorderedListItem">Test messages asking about side effects and taking anti-estrogen therapy, monthly, for 9 months</li> <li class="seamTextUnorderedListItem">Questionnaires </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online education about anti-estrogen therapy, 1 time</li> <li class="seamTextUnorderedListItem">Motivational telephone therapy sessions, 5 times, over 9 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online education about anti-estrogen therapy, 1 time</li> <li class="seamTextUnorderedListItem">Text message reminders to take anti-estrogen therapy, daily, for 9 months</li> <li class="seamTextUnorderedListItem">Test messages asking about side effects and taking anti-estrogen therapy, monthly, for 9 months</li> <li class="seamTextUnorderedListItem">Motivational telephone therapy sessions, 5 times, over 9 months</li> <li class="seamTextUnorderedListItem">Questionnaires </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 4</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online education about anti-estrogen therapy, 1 time</li> <li class="seamTextUnorderedListItem">Optional online education about healthy living</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial is studying whether text messaging, online education, and telephone support can help women take their anti-estrogen therapy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04379570' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal/expect' target='_blank'>Breastcancer.org: Hormonal Therapy, What to Expect</a> </li></ul>
2
Tools to Improve Nutrition and Physical Activity After Treatment for People with Stage I-III Breast Cancer
Optimizing Intervention Tools to Improve Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit) (TTBF) Scientific Title
Purpose
To study how 4 different support tools impact body weight, nutrition, and physical activity.
Who is this for?
People with stage I, stage II, or stage III breast cancer who have completed treatment (except for hormone therapy).
Full eligibility criteria
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<p class="seamTextPara"> You will receive a personalized report at the start of the study and then be randomly assigned to receive one or more of the following tools for approximately 1 year: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A digital health tool kit or a food and exercise logbook</li> <li class="seamTextUnorderedListItem">Text messages</li> <li class="seamTextUnorderedListItem">Health coaching sessions</li> <li class="seamTextUnorderedListItem">Health coaching sessions for your support person</li> </ul> <p class="seamTextPara"> You will complete surveys on your background and health at the start of the study and update your health information a few times throughout the study.</p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">People with a history of cancer whose nutrition and physical activity habits are consistent with the American Cancer Society's guidelines may live longer without cancer coming back (recurrence).</li> <li class="seamTextUnorderedListItem">The four components of the program being studied may help people with a history of cancer adopt recommended health behaviors after they have completed treatment.</li> <li class="seamTextUnorderedListItem">A support person of your choice will also participate in this study.</li> <li class="seamTextUnorderedListItem">This trial is enrolling people with other types of cancer.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05056077' target='_blank'>ClinicalTrials.gov</a> </li></ul>
3
Impact of DCISionRT Test on Treatment Decisions for Women with DCIS and LCIS
A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy (PREDICT) Scientific Title
Purpose
To study the impact of the DCISionRT test on treatment decisions for people with DCIS or LCIS.
Who is this for?
Women 30-85 years old with stage 0 (DCIS or LCIS) breast cancer who were diagnosed in the last 4 months and are planning to receive or have received a lumpectomy. You must have received the DCISionRT test.
Full eligibility criteria
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<p class="seamTextPara"> You will provide access to the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Health data</li> <li class="seamTextUnorderedListItem">Imaging data</li> <li class="seamTextUnorderedListItem">Tissue samples</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The DCISionRT test predicts the risk of recurrence over 10 years and the benefit from radiation therapy.</li> <li class="seamTextUnorderedListItem">Your doctor will complete surveys before and after receiving the DCISionRT test. The surveys will study how the DCISionRT test results were used to make treatment decisions.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03448926' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://preludedx.com/patients/' target='_blank'>PreludeDx: DCISionRT</a> </li></ul>
4
Studying the Relationship Between Inherited KRAS Mutations and Breast Cancer Risk
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment Scientific Title
Purpose
To study the relationship between the KRAS mutation and cancer risk.
Who is this for?
People with stage I, stage II, stage III, and stage IV (metastatic) breast cancer, or people with a family history of breast cancer. You must also have endometriosis or an autoimmune condition.
Full eligibility criteria
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saliva sample to test for the KRAS mutation</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">An inherited KRAS genetic mutation may increase a person's risk of developing breast or other types of cancer.</li> <li class="seamTextUnorderedListItem">This study will follow participants for 10 years. </li> <li class="seamTextUnorderedListItem">The researchers will also look at the effect that different lifestyle factors have on cancer risk. </li> <li class="seamTextUnorderedListItem">Participants will be able to get their KRAS mutation test results after submitting their sample at a discounted cost ($295).</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02253251' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://miradx.com/test/kras-variant/' target='_blank'>MiraKind Research Company: KRAS-Variant</a> </li><li class='seamTextUnorderedListItem'><a href='http://mirakind.org/study-eligibility-questionnaire/' target='_blank'>Research Company: Eligibility Survey</a> </li></ul>
5
Predicting Pain After Surgery for Stage I-III Breast Cancer
Development of Predictive Models Using Artificial Intelligence for Postoperative Chronic Pain and Opioid Use Following Breast Surgery: A Prospectively-Designed Study Scientific Title
Purpose
To collect data to predict who will experience chronic pain after breast surgery.
Who is this for?
People with stage I, stage II, or stage III breast cancer who are planning to receive a mastectomy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires</li> <li class="seamTextUnorderedListItem">Mouth swab</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast surgery may lead to chronic (long term) pain in many people.</li> <li class="seamTextUnorderedListItem">Personalized pain management may control pain with the least amount of medications.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04967352' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/treatment/side-effects/managing-pain/' target='_blank'>Susan G Komen: Pain From Breast Surgery</a> </li></ul>
6
Text Messaging and Website to Improve Sleep Problems for Women with Stage I-III Breast Cancer
A Crossover Randomized Controlled Trial to Investigate the Acceptability and Efficacy of Cecebot, a Conversational Agent for Insomnia After Breast Cancer Scientific Title
Purpose
To study the ability of text message conversations with a chatbot to improve sleep problems.
Who is this for?
Women with stage I, stage II, or stage III breast cancer who have completed treatment and have sleep problems.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Immediate Start</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Sleep education text message conversations with chatbot, 2-4 times every week</li> <li class="seamTextUnorderedListItem">Sleep education website, 2-4 times every week</li> <li class="seamTextUnorderedListItem">Wear activity tracker, daily for 1.5 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Delayed Start</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">No intervention for 1.5 months</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Sleep education text message conversations, 2-4 times every week</li> <li class="seamTextUnorderedListItem">Sleep education website, 2-4 times every week</li> <li class="seamTextUnorderedListItem">Wear activity tracker, daily for 1.5 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Sleep disturbance is a top concern of breast cancer survivors and is associated with poor quality of life. </li> <li class="seamTextUnorderedListItem">Many breast cancer survivors also have decreased physical activity, which may also have a negative impact on sleep and quality of life. </li> <li class="seamTextUnorderedListItem">Cognitive behavioral therapy (CBT) is a type of therapy that focuses on the relationship between thoughts, feelings, and behaviors.</li> <li class="seamTextUnorderedListItem">The chatbot in this study is called Cecebot and is a personalized text message-based behavioral intervention that combines cognitive behavioral therapy and exercise with the goal of improving sleep.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06392789' target='_blank'>ClinicalTrials.gov</a> </li></ul>
7
Online Meditation to Reduce Anxiety and Depression After Treatment for Women with Stage I-III Breast Cancer
The SUPORT Project: Leveraging Social Connection by Including Informal Caregivers in an Internet Video Conference-based Compassion Meditation Intervention to Reduce Psychological Distress in Breast Cancer Survivors Scientific Title
Purpose
To study if meditation with or without caregivers will reduce depression and anxiety in breast cancer survivors.
Who is this for?
Women with stage I, stage II, or stage III breast cancer who completed treatment between 3 months and 5 years ago. You may still be receiving hormone therapy or trastuzumab (Herceptin®). You must have a partner or caregiver who lives with you and is willing to participate.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 3 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Meditation sessions without your partner, virtual, weekly for 2 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Meditation sessions with your partner, virtual, weekly for 2 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3: Health Education</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Health education sessions with your partner, virtual, weekly for 2 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Many breast cancer survivors (around 70%) experience depression and/or anxiety after finishing cancer treatments.</li> <li class="seamTextUnorderedListItem">Meditation may reduce feelings of anxiety and depression.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05676255' target='_blank'>ClinicalTrials.gov</a> </li></ul>
8
Counseling by Phone to Help Manage Side Effects of Immunotherapy for Stage II-IV Breast Cancer
Adaptive Symptom Self-Management to Reduce Psychological Distress and Improve Symptom Management for Survivors on Immune Checkpoint Inhibitors Scientific Title
Purpose
To study whether telephone-based counseling will improve your ability to manage immunotherapy side effects.
Who is this for?
People with stage II, stage III, or stage IV (metastatic) breast cancer who have begun treatment with an immune checkpoint inhibitor within the past 3 months. You must be experiencing at least mild psychological distress.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Counseling, by phone call, weekly</li> <li class="seamTextUnorderedListItem">Handbook about managing side effects</li> <li class="seamTextUnorderedListItem">Assessment of side effects, weekly</li> <li class="seamTextUnorderedListItem">Interviews, 2 times within 4 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Assessment of side effects, weekly</li> <li class="seamTextUnorderedListItem">Interviews, 2 times within 4 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Immunotherapies are drugs that trigger the immune system to see, go after, and kill cancer cells.</li> <li class="seamTextUnorderedListItem">Side effects from immunotherapy are common.</li> <li class="seamTextUnorderedListItem">The ability to manage the side effects you experience from immunotherapy may reduce your distress, prevent treatment interruption, and lead to fewer visits to your doctor.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05715255' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/cancer/types/breast-cancer/treatment/immunotherapy.html#:~:text=Possible%20side%20effects%20of%20immune,reaction%20while%20getting%20these%20drugs.' target='_blank'>American Cancer Society: Immune Checkpoint Inhibitors for Breast Cancer and Their Side Effects</a> </li></ul>
9
Support Improving Treatment Completion for People in Rural Counties with Stage I-III Breast Cancer
Improving the Timeliness and Quality of Care for Rural Patients With Solid Tumors Scientific Title
Purpose
To study if the CARES intervention improves the time to start and complete treatment for people living in rural counties.
Who is this for?
People with stage I, stage II, or stage III breast cancer who live in a rural county and are planning to receive treatment at University of Colorado Health System. You must have no insurance or not enough insurance.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive CARES navigation and counseling, virtually or in person, up to 20 times within 6 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive list of resources</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The CARES (Cancer Advocacy, Resources, Education and Support) intervention includes up to 10 navigation and 10 counseling sessions provided by oncology nurses and counselors. </li> <li class="seamTextUnorderedListItem">CARES sessions will be scheduled during key treatment transition points.</li> <li class="seamTextUnorderedListItem">This study is also enrolling people with other types of cancer.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04916990' target='_blank'>ClinicalTrials.gov</a> </li></ul>
10
Online Program to Improve Attitudes About Hormone Therapy for Women with Stage 0-III HR+ Breast Cancer
Pilot Study of Positive Affect Training for Endocrine Therapy Medication Adherence (THRIVE) Scientific Title
Purpose
To study the THRIVE online behavioral program that aims to increase positive attitudes and decrease negative attitudes toward hormone therapy.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III hormone receptor positive (ER+ and/or PR+) breast cancer who have completed treatment. You must be receiving or recommended to receive hormone therapy and have concerns about hormone therapy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">THRIVE behavioral program, online</li> <li class="seamTextUnorderedListItem">Surveys</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Hormone therapy blocks the body's production of estrogen or response to estrogen.</li> <li class="seamTextUnorderedListItem">Side effects of hormone therapy may include bone or joint pain, hot flashes, fatigue, mood swings, and nausea.</li> <li class="seamTextUnorderedListItem">The THRIVE behavioral intervention is based on Positive Affect Training (PAT) and aims to improve attitudes about hormone therapy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06388304' target='_blank'>ClinicalTrials.gov</a> </li></ul>
11
Survey to Understand Breast Cancer Screening Knowledge and Attitudes
Promoting Informed Choice for Breast Cancer Screening: A Longitudinal Study Scientific Title
Purpose
To study attitudes and knowledge about breast cancer screening and to determine if conversations with primary care doctors increase breast cancer screening.
Who is this for?
Women 39-49 years old who have not been diagnosed with breast cancer and do not have a known BCRA1/2 gene mutation.
Full eligibility criteria
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Surveys, by email or phone, 4 times within 1 year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Conversations between primary care doctors and healthy women may affect women's attitudes and understanding of breast cancer screening and therefore may increase screening.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05838417' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/screening-testing/mammograms/recommendations' target='_blank'>Breastcancer.org: Mammogram Screening Guidelines</a> </li></ul>
12
Studying Alopecia During Hormone Therapy in Women with Breast Cancer
Endocrine Therapy-Induced Alopecia Natural History Evaluation Among Female Breast Cancer Survivors Scientific Title
Purpose
To study the incidence, timing, duration, and severity of alopecia (hair loss) during hormone therapy.
Who is this for?
Women with stage I, stage II, or stage III hormone receptor positive (ER+ and/or PR+) breast cancer who are receiving or planning to receive hormone therapy.
Full eligibility criteria
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires, every 3 months for 2 years</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">While alopecia (hair loss) is a well-known side effect of many chemotherapy drugs, it has also been reported by women undergoing hormone therapy.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05612100' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment-side-effects/hair-loss' target='_blank'>Breastcancer.org: Alopecia/Hair Loss</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy' target='_blank'>Breastcancer.org: Hormone Therapy</a> </li></ul>
13
Online Pain and Depression Support Program for Asian Women with Stage I-IV Breast Cancer
Cancer Pain Management: A Technology-Based Intervention for Asian American Breast Cancer Survivors (CAI) Scientific Title
Purpose
To study if an online pain and depression management program can support Asian women with breast cancer.
Who is this for?
Chinese, Korean, or Japanese women who were diagnosed with breast cancer in the past and are experiencing pain and depression.
Full eligibility criteria
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: CAI (Web App Based, Individualized Coaching and Support Program for Cancer Pain)</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Personalized information and support program, online</li> <li class="seamTextUnorderedListItem">Fitbit</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: CAPA (Web App Based Information and Coaching/Support Program for Cancer Pain Management)</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">General information and support program, online</li> <li class="seamTextUnorderedListItem">Fitbit</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem"> The pain and depression management program provides web-based information, coaching, and support that is culturally tailored to Asian American women with breast cancer.</li> <li class="seamTextUnorderedListItem">This trial is also available in Mandarin (simplified or traditional), Korean, and Japanese.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06085313' target='_blank'>ClinicalTrials.gov</a> </li></ul>
14
Susan G. Komen ShareForCures Research Registry
ShareForCures: Susan G. Komen's People-powered, Data-driven Breast Cancer Research Registry Scientific Title
Purpose
To create a research registry of data from people with breast cancer, including minority and marginalized people, to ensure data is as diverse as the people touched by the disease.
Who is this for?
People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will provide the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Tissue samples</li> <li class="seamTextUnorderedListItem">Blood samples</li> <li class="seamTextUnorderedListItem">Saliva samples</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Researchers will have a better understanding of breast cancer and everyone can potentially benefit from scientific advances and improvements in care.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05654246' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/shareforcures/' target='_blank'>Susan G. Komen: ShareForCures</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/cancer/npcr/value/registries.htm' target='_blank'>Centers for Disease Control and Prevention: How Cancer Registries Work</a> </li></ul>
15
Understanding How Cancer Treatment Affects Musicians
Defining Musical Toxicity and Its Effect on Patient Well-being Scientific Title
Purpose
To study the experience of musicians who are going through cancer treatment.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are planning to receive or are receiving treatment. You must also be a musician.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Interview</li> <li class="seamTextUnorderedListItem">Questionnaire</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial defines musicians as people who identify with one of the following: those performing in the community as part of a group or as a soloist; those teaching lessons in an individual or group setting; those for whom music teaching or performance is a primary source of income; those who play music multiple times per week.</li> <li class="seamTextUnorderedListItem">Musical difficulties that happen during and after cancer treatments is called <q>musical toxicity</q>.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06494046' target='_blank'>ClinicalTrials.gov</a> </li></ul>
16
Care and Monitoring at Home for People with Brain Metastasis
Neuro-Oncology Anywhere: Deploying Mayo Clinic's Remote Cognitive Assessment Battery and Wearable Device Monitoring Platform While Assessing the Impact of Metformin on Cognition and Quality of Life in Patients With History of Cranial Radiation Scientific Title
Purpose
To study if giving metformin and monitoring can be done at home for people receiving brain radiation or who have previously had brain radiation.
Who is this for?
People with metastatic (stage IV) breast cancer that has spread to the brain (brain metastasis). You must be planning to receive brain radiation or completed brain radiation within the last 3 years.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Metformin, by mouth, daily, 1 year</li> <li class="seamTextUnorderedListItem">FitBit wearable device</li> <li class="seamTextUnorderedListItem">Cognitive tests</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care treatment, 1 year</li> <li class="seamTextUnorderedListItem">FitBit wearable device</li> <li class="seamTextUnorderedListItem">Cognitive tests</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Brain radiation can result in significant negative effects on cognition (the ability to clearly think, learn, and remember).</li> <li class="seamTextUnorderedListItem">Cognitive tests study your cognition, which is your ability to think.</li> <li class="seamTextUnorderedListItem">Metformin is a drug approved to treat type 2 diabetes (a condition in which the body cannot control the level of sugar in the blood).</li> <li class="seamTextUnorderedListItem">Metformin may also be used to treat cancer and improve your cognition (ability to think) and quality of life.</li> <li class="seamTextUnorderedListItem">In this study, a FitBit wearable device will be used to monitor and detect seizures.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06377696' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://mbcbrainmets.org/' target='_blank'>MBCBrainMets.org</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayo.edu/research/clinical-trials/cls-20567690' target='_blank'>Mayo Clinic: Trial Information Page</a> </li></ul>
17
Questionnaires to Understand Financial Impacts of Surgery and COVID-19 for Women Receiving a Mastectomy
Financial Toxicity in Patients Undergoing Breast Reconstruction: The Impact of Out of Pocket Costs, Lost Wages and Unemployment Scientific Title
Purpose
To collect information about the financial impact of breast cancer surgery and to learn if the COVID-19 pandemic affects patient costs of breast reconstruction.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women at high risk for breast cancer who are planning to receive a mastectomy and breast reconstruction at MD Anderson Cancer Center.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires, virtual, 4 times within 2 years</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">People receiving breast reconstruction after a mastectomy are at high risk for financial toxicity (harmful effects of high health care cost on well-being).</li> <li class="seamTextUnorderedListItem">The COVID-19 pandemic may affect these costs.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04169542' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/resources-support/find-financial-support-cancer/' target='_blank'>Metastatic Trial Talk: Where to Find Financial Support</a> </li></ul>
18
Writing to Heal: Writing Intervention After Treatment for Chinese-Born Women with Stage 0-III Breast Cancer
Writing to Heal: A Culturally Based Brief Expressive Writing Intervention for Chinese Immigrant Breast Cancer Survivors Scientific Title
Purpose
To determine the health benefits of a culturally-based expressive writing intervention for Chinese-born women after treatment.
Who is this for?
Chinese-born women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer who completed treatment less than 5 years ago. You must have lived in the US for at least 6 months.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 3 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Write about diagnosis and treatment, weekly for 3 weeks</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Write about stress, coping, and emotions, weekly for 3 weeks</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Write about positive thoughts and feelings about cancer experience, weekly for 3 weeks</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Culturally-based brief expressive writing interventions may help researchers learn more about the experiences of Chinese immigrant breast cancer survivors and how writing about their experiences may affect their health.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04754412' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mdanderson.org/publications/cancer-frontline/2019/expressive-writing-improves-quality-of-life-for-breast-cancer-su.html' target='_blank'>MD Anderson Cancer Center: Expressive writing improves quality of life for breast cancer survivors</a> </li></ul>
19
Phone Survey to Improve Telemedicine Visits for Brain Metastasis
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology Scientific Title
Purpose
To compare opinions of telemedicine (virtual) visits and in-person visits to improve telemedicine (virtual) visits.
Who is this for?
People with metastatic (stage IV) breast cancer that has spread to the brain (brain metastases) who had at least 2 visits at the MD Anderson Cancer Center Brain and Spine Center.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Survey, by phone</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">During the phone survey, you will be asked about your opinions on the quality of care you received at your telemedicine (virtual) or in-person visits.</li> <li class="seamTextUnorderedListItem">Telemedicine visits are also called virtual visits.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04988009' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://mbcbrainmets.org/' target='_blank'>MBCBrainMets.org</a> </li></ul>
20
Empowerment and Navigation Sessions for Latina Women Ages 30+ with Breast Cancer or a Family History of Breast/Ovarian Cancer
Empowering Vulnerable and Resilient Latinas to Obtain Breast Cancer Care Scientific Title
Purpose
To compare the impact of empowerment and navigation sessions with standard of care sessions on whether Latina women decide to receive genetic testing and/or genetic counseling.
Who is this for?
Latina women ages 30+ with stage I, stage II, stage III, or stage IV (metastatic) breast cancer or with a family history of breast or ovarian cancer. You must have one social determinant of health risk factor, such as: perceived financial struggles, transportation difficulties, exposure to violence, housing challenges, social isolation/challenges. You must not have received genetic testing or genetic counseling.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Standard of care sessions, by phone, 3 times within 3 weeks</li> <li class="seamTextUnorderedListItem">Personalized educational materials</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Empowerment and navigation sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, breast cancer screening, and diet and physical activity for breast cancer prevention.</li> <li class="seamTextUnorderedListItem">Standard of care sessions will discuss social determinants of heath, genetic risk factors, individual behavior change action plans, how to share breast cancer information, and testimonials and include role playing activities and group discussions.</li> <li class="seamTextUnorderedListItem">You can receive up to $100 for participation.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05483283' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/cancer-prevention-and-early-detection-facts-and-figures/making-the-case-for-health-equity.pdf' target='_blank'>American Cancer Society: Health Equity and Social Determinants of Health</a> </li><li class='seamTextUnorderedListItem'><a href='https://health.gov/healthypeople/priority-areas/social-determinants-health' target='_blank'>US Department of Health and Human Services: Social Determinants of Health</a> </li></ul>
21
WeCanManage App to Help People with Disabilities After Breast Cancer Treatment
WeCanManage: An mHealth Self-management Tool to Empower Survivors With Disabilities Due to Long-term Effects of Cancer and Its Treatment Scientific Title
Purpose
To study if the WeCanManage app can help people with disabilities manage their cancer.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, or some stage III breast cancer who have completed treatment (except for hormone therapy) and who have a disability.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaire, by phone, 3 times</li> <li class="seamTextUnorderedListItem">WeCanManage app introduction, virtual, 1 time</li> <li class="seamTextUnorderedListItem">WeCanManage app, daily for 1-1.5 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The app contains 4 sections: WeCanRelate, WeCanAdapt, WeCanBe, and WeCanSpeakUp.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06185738' target='_blank'>ClinicalTrials.gov</a> </li></ul>
22
Web-Based Coping Skills Training to Decrease Pain from Hormone Therapy
Web-based Pain Coping Skills Training to Improve Pain and Poor Adherence Caused by Aromatase Inhibitor-Associated Arthralgia In Breast Cancer Survivors (SKIP-Arthralgia): A Randomized Controlled Trial Scientific Title
Purpose
To study if an online pain coping skills training program reduces the severity and effects of pain from treatment with aromatase inhibitors.
Who is this for?
Postmenopausal women with stage I, stage II, or stage III hormone receptor positive (ER+ and/or PR+) breast cancer who have completed treatment. You must be taking an aromatase inhibitor and experience pain in your joints, bones, and/or muscles.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online pain coping skills training program, weekly for 2-3 months</li> <li class="seamTextUnorderedListItem">Educational booklet about aromatase inhibitors and side effects</li> <li class="seamTextUnorderedListItem">Electronic pill bottle to track use of aromatase inhibitor medication</li> <li class="seamTextUnorderedListItem">Continue usual care</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Educational booklet about aromatase inhibitors and side effects</li> <li class="seamTextUnorderedListItem">Electronic pill bottle to track use of aromatase inhibitor medication</li> <li class="seamTextUnorderedListItem">Continue usual care</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Additional Procedures</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires, 4 times within 9-10 months</li> <li class="seamTextUnorderedListItem">Virtual visits, 3 times within 1 month</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Aromatase inhibitors are a type of hormone therapy that block some production of estrogen that helps cancer grow. Approved aromatase inhibitors include anastrozole (Arimidex®), letrozole (Femara®), and exemestane (Aromasin®).</li> <li class="seamTextUnorderedListItem">Arthralgia is pain in the joints, bones, and/or muscles and is a common side effect of aromatase inhibitors.</li> <li class="seamTextUnorderedListItem">The online pain coping skills training is an interactive, web-based program that teaches cognitive and behavioral skills to reduce pain and pain-related interference with daily activities. The program includes 8 sessions that are 35-45 minutes each. You will complete about 1 session per week.</li> <li class="seamTextUnorderedListItem">If you do not have a device capable of accessing the program, you will be loaned a tablet computer for the study.</li> <li class="seamTextUnorderedListItem">Benefits of the online pain coping skills training may include reduced severity of pain, improvements in quality of life, and improved adherence to aromatase inhibitor medication. The training may also increase your confidence in managing your pain and reduce unhelpful thinking patterns about pain.</li> <li class="seamTextUnorderedListItem">The educational booklet contains information about aromatase inhibitors, side effects including arthralgia, methods for managing arthralgia, and tips for talking with doctors about arthralgia and other side effects.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05703178' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.scholars.northwestern.edu/en/projects/web-based-pain-coping-skills-training-to-improve-pain-and-poor-ad' target='_blank'>Northwestern University: Pain Coping Skills Training</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy/aromatase-inhibitors' target='_blank'>Breastcancer.org: Aromatase Inhibitors</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/treatment/type/hormone-therapy/aromatase-inhibitors/side-effects/' target='_blank'>Susan G Komen: Side Effects of Aromatase Inhibitors</a> </li></ul>
23
Websites to Improve Communication About Cancer Risk and Screening for People at Risk for Breast Cancer
Improving Care After Inherited Cancer Testing (IMPACT) Study Scientific Title
Purpose
To study the use of 2 websites to improve management of cancer risk and communication with family members about genetic test results.
Who is this for?
People who have a genetic risk factor for breast cancer and meet at least 1 of the following criteria: 1) Have at least 1 relative who does not know your genetic risk results; 2) Have at least 1 relative who has not received genetic testing; 3) Are not following recommended cancer screening; or 4) Require ongoing cancer screening.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 3 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Access to GeneSHARE website</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews (optional)</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Access to LivingLabReport website</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews (optional)</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 3: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care</li> <li class="seamTextUnorderedListItem">Surveys</li> <li class="seamTextUnorderedListItem">Interviews (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">GeneSHARE is a website with a toolkit designed to enhance communication with family members about genetic test results.</li> <li class="seamTextUnorderedListItem">LivingLabReport is a website with resources including your genetic test results, disease specific information, recommended cancer risk management, and information on accessing cancer risk management services.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with genetic risk for ovarian, pancreatic, or colorectal cancers.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04763915' target='_blank'>ClinicalTrials.gov</a> </li></ul>
24
Coaching Program to Reduce Stress and Promote Resilience for People with Metastatic Breast Cancer
Promoting Resilience in Stress Management for Metastatic Breast Cancer (PRISM-MBC PRISMMBC) Scientific Title
Purpose
To study the ability of the PRISM program to reduce stress and improve resilience for people with metastatic breast cancer.
Who is this for?
People with stage IV (metastatic) breast cancer who were diagnosed with metastatic disease in the last 6 months.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Promoting Resilience in Women with Breast Cancer (PRISM) program, virtual, 4 sessions in 1-2 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Promoting Resilience in Women with Breast Cancer (PRISM) program helps improve 4 areas of resilience: stress management, goal setting, cognitive reframing, and meaning-making.</li> <li class="seamTextUnorderedListItem">This study will compare the resilience of Black women to non-Black women.</li> <li class="seamTextUnorderedListItem">It also includes an optional family session.</li> <li class="seamTextUnorderedListItem">Each session is 30-60 minutes every 1-2 weeks.</li> <li class="seamTextUnorderedListItem">Black women with MBC have worse outcomes than white women with MBC because of social determinants of health (SDOH).</li> <li class="seamTextUnorderedListItem">Social determinants of health (SDOH) describe non-medical factors that influence your health, such as race, gender identity, education, occupation, transportation, food and health access, medication affordability, safety at home, housing, and financial stability.</li> <li class="seamTextUnorderedListItem">Reducing stress and improving resilience during MBC treatment may improve quality of life and even improve disease outcomes.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06855654' target='_blank'>ClinicalTrials.gov</a> </li></ul>
25
Improving Quality of Life of Young Black Women After Treatment
Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors Scientific Title
Purpose
To compare how Y-AMBIENT education sessions and follow up phone calls improve quality of life after breast cancer treatment.
Who is this for?
Black or African American women ages 18 to 44 years old with stage I, stage II, or stage III breast cancer who have completed treatment with chemotherapy and/or radiation.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Y-AMBIENT education sessions, 3 times within 4 months</li> <li class="seamTextUnorderedListItem">Y-AMBIENT follow up phone calls, 3 times within 4 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education sessions, 3 times within 4 months</li> <li class="seamTextUnorderedListItem">Follow up phone calls, 3 times within 4 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Additional Procedures</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Y-AMBIENT is telephone-based intervention with education sessions designed to improve quality of life. Session 1, titled <q>My Self, My Soul,</q> covers topics related to spiritual growth and finding meaning in illness. Session 2, titled <q>My Body,</q> covers topics related to breast changes, aches/pains, fatigue, and weight changes. Session 3, titled <q>My Mind and My Relationships,</q> covers topics related to anxiety, fear, and relationships with others.</li> <li class="seamTextUnorderedListItem">If you are in Group 2, education sessions include a culturally-targeted cookbook and a guide to grocery shopping smart.</li> <li class="seamTextUnorderedListItem">For both groups, all sessions will take approximately one hour, and follow-up phone calls will last about 20 minutes.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05452681' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/survivorship/health-concerns/quality-of-life/#:~:text=Quality%20of%20life%20after%20treatment,even%20years%20after%20treatment%20ends.' target='_blank'>Susan G. Komen: Quality of Life After Breast Cancer Treatment</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/pcd/issues/2016/16_0096.htm' target='_blank'>Centers for Disease Control and Prevention: Quality of Life of Black Breast Cancer Survivors</a> </li></ul>
26
Healthy Eating and Nutrition Counseling to Improve Cognition During Chemotherapy for Women with Stage II-III Triple Negative Breast Cancer
Food for Thought - Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Triple Negative Breast Cancer (MIND-TNBC) Scientific Title
Purpose
To study if the MIND eating plan can improve memory and mental function, fatigue, sleep quality, anxiety, and depression.
Who is this for?
Women 40-65 years old with stage II or stage III triple negative (ER-, PR-, HER2-) breast cancer who are receiving (within the past 6 months) or planning to receive chemotherapy before surgery (neoadjuvant).
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MIND counseling sessions, virtual, weekly for 1 month, then every 2 weeks for 2 months</li> <li class="seamTextUnorderedListItem">Personalized eating plan, 3 months</li> <li class="seamTextUnorderedListItem">Wear a FitBit</li> <li class="seamTextUnorderedListItem">Cognitive tests, 2 times in 6 months</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">General health sessions, virtual, weekly for 1 month, then every 2 weeks for 2 months</li> <li class="seamTextUnorderedListItem">Wear a FitBit</li> <li class="seamTextUnorderedListItem">Cognitive tests, 2 times in 6 months</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> <p class="seamTextPara"> followed 6 months later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MIND counseling sessions, virtual, weekly for 1 month, then every 2 weeks for 2 months</li> <li class="seamTextUnorderedListItem">Personalized eating plan, 3 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cancer treatment can lead to cognition (ability to think) problems and low quality of life.</li> <li class="seamTextUnorderedListItem">The Neurodegenerative Delay (MIND) eating plan is high in anti-inflammatory nutrients (omega-3, carotenoids, B vitamins, etc.) and limits foods that are not healthy for the brain (butter, cheese, red meat, fried foods, sugar, etc.).</li> <li class="seamTextUnorderedListItem">The MIND eating plan may help improve brain function during cancer treatment.</li> <li class="seamTextUnorderedListItem">In this trial, you will be sent some of the main foods in the MIND eating plan.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06582615' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://health.osu.edu/wellness/exercise-and-nutrition/the-mind-diet' target='_blank'>Ohio State University: The MIND Diet and Brain Health</a> </li></ul>
27
Improving Quality of Life for Young African American Women with Stage I-III Breast Cancer
Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment Scientific Title
Purpose
To study if Y-AMBIENT education sessions help African American women with breast cancer manage daily life.
Who is this for?
Black or African American women 18-44 years old with stage I, stage II, or stage III breast cancer who are receiving chemotherapy and/or radiation.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Y-AMBIENT education sessions, by phone, 3 sessions within 4 months</li> <li class="seamTextUnorderedListItem">Phone calls discussing treatment and concerns, 3 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Enhanced Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Phone calls discussing treatment and concerns, 3 times within 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Y-AMBIENT is a telephone-based intervention that includes three themed education sessions with three follow-up sessions, written materials, and videos.</li> <li class="seamTextUnorderedListItem">The Y-AMBIENT sessions are 1 hour each and may improve quality of life and other health-related outcomes.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05243056' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/managing-life' target='_blank'>Breastcancer.org: Managing Life With Cancer</a> </li></ul>
28
Web App to Improve Adherence to Hormone Therapy for People with Stage I-III HR+, HER2- Breast Cancer
A Feasibility Trial of a Web Based App Intervention in Hormone Positive Breast Cancer Patients to Improve Adherence to Endocrine Therapy Scientific Title
Purpose
To study the ability of a web app to improve your ability to take hormone therapy on time as prescribed.
Who is this for?
People with stage I, stage II, or stage III hormone receptor positive (HR+), HER2 negative (HER2-) breast cancer who have begun treatment with an aromatase inhibitor or tamoxifen (Nolvadex®) less than 6 months ago.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Web app, 3 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Adherence is your ability to take medication on time as prescribed.</li> <li class="seamTextUnorderedListItem">Through the app, you will receive weekly reminders about hormone therapy, report any side effects, and watch videos with tips to help reduce side effects.</li> <li class="seamTextUnorderedListItem">In the app, you can also send messages with questions about the side effects you may be experiencing.</li> <li class="seamTextUnorderedListItem">Anastrozole (Arimidex®), letrozole (Femara®), and exemestane (Aromasin®) are types of hormone therapy called aromatase inhibitors. Aromatase inhibitors block some production of estrogen that helps cancer grow.</li> <li class="seamTextUnorderedListItem">Tamoxifen (Nolvadex®) is a type of hormone therapy called a selective estrogen receptor modulator (SERM). SERMs work by blocking the activity of estrogen.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05488145' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy' target='_blank'>Breastcancer.org: Hormone Therapy</a> </li></ul>
29
Understanding Patient Reported Outcomes for Young Adults with Stage I-III Breast Cancer
Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials Scientific Title
Purpose
To understand the most important patient reported outcomes (PROs) for young adults with cancer and how best to ask about PROs.
Who is this for?
People 18-39 years old who were diagnosed with stage I, stage II, or stage III breast cancer in the last 3 months.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Rank most important patient reported outcomes</li> <li class="seamTextUnorderedListItem">Choose 5 PRO surveys to complete, 5 times in 1 year</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Rank most important patient reported outcomes</li> <li class="seamTextUnorderedListItem">Complete 5 pre-selected PRO surveys, 5 times in 1 year</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A patient reported outcome (PRO) is information reported during a clinical trial by a person with breast cancer without interpretation by a doctor or anyone else.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05108298' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ecog-acrin.org/clinical-trials/eaq202-various-cancer/' target='_blank'>Eastern Cooperative Oncology Group: Trial Information Page</a> </li></ul>
30
Quality of Life Survey for Young Women After Breast Cancer Treatment
Factors Affecting Quality of Life and Treatment Adherence Among Early-Age-at-Onset Breast Cancer Survivors Scientific Title
Purpose
To study the quality of life of women after completing breast cancer treatment.
Who is this for?
Women with stage I, stage II, or stage III breast cancer who have completed treatment. You must have been diagnosed within the past 10 years and diagnosed before age 50.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Complete online survey</li> <li class="seamTextUnorderedListItem">You will be entered to win a $50 electronic gift card in appreciation for your time</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">If you are interested in participating, reach out to Dr. Susan Steck at stecks@mailbox.sc.edu or 803-777-1527.</li> <li class="seamTextUnorderedListItem">The survey will ask about factors that impact your quality of life, such as your diet and social determinants of health (SDOH).</li> <li class="seamTextUnorderedListItem">Social determinants of health (SDOH) describe non-medical factors that influence your health, such as race, gender, education, work, and access to resources.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05981716' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://ybcss2.org/' target='_blank'>Trial Information Page: Young Breast Cancer Survivor Study (YBCSS)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/survivorship/health-concerns/quality-of-life/' target='_blank'>Susan G. Komen: Quality of Life After Breast Cancer Treatment</a> </li></ul>
31
Questionnaires to Prevent Treatment Delays for People with Newly Diagnosed Stage I-IV Breast Cancer
The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparities in Cancer Treatment Delay Scientific Title
Purpose
To understand when patients may be at risk of treatment delays and to help patients get treatment faster.
Who is this for?
People with newly diagnosed stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have been diagnosed within the past 1.5 months and are planning to receive treatment at the University of North Carolina.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Patient reported outcome (PRO) questionnaires, weekly for 2 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A patient reported outcome (PRO) is information reported during a clinical trial by a person with breast cancer without interpretation by a doctor or anyone else.</li> <li class="seamTextUnorderedListItem">The questionnaires will identify social determinants of health (SDOH), the non-medical factors that influence your health, such as race, gender identity, education, occupation, access to health services and economic resources.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06096623' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.net/blog/2023-06/what-are-patient-reported-outcomes-and-why-are-they-important-cancer-care' target='_blank'>Cancer.Net: What Are Patient-Reported Outcomes and Why Are They Important in Cancer Care?</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/about/sdoh/index.html' target='_blank'>Centers for Disease Control and Prevention: Social Determinants of Health (SDOH)</a> </li></ul>
32
Mobile Weight Loss Program and Support for Adolescents and Young People with Stage I-III Breast Cancer
A Pilot Randomized Trial of a Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors (AYAConnect) Scientific Title
Purpose
To study a mobile weight loss program for adolescent and young adult (AYA) breast cancer survivors.
Who is this for?
People 18-39 years old with stage I, stage II, or stage III breast cancer who have completed treatment. You must have been diagnosed within the last 10 years and have a BMI of at least 25 kg/m2.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The AYA Connect programs use a mobile smartphone app, previously developed for individuals at risk for type 2 diabetes, that integrates weight and physical activity from digital devices with simplified dietary monitoring.</li> <li class="seamTextUnorderedListItem">The app includes weekly behavioral lessons, dietary tracking log, daily weight-related behavioral goals, tailored feedback summaries, and in-app health-related messages.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06171945' target='_blank'>ClinicalTrials.gov</a> </li></ul>
33
CSC Online Survey: The Cancer Experience Registry
Cancer Experience Registry: An Online Initiative to Understand the Experiences of Those Impacted by a Cancer Diagnosis (CER) Scientific Title
Purpose
To learn more about the emotional and social experiences and needs of people affected by cancer.
Who is this for?
People diagnosed with DCIS, stage I, stage II, stage III, or metastatic (stage IV) breast cancer and people who provide care to individuals diagnosed with cancer.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> Participation in this study involves the completion of an online questionnaire. The questionnaire may be accessed at the following link: </p> <a href="http://www.cancersupportcommunity.org/MainMenu/ResearchTraining/Cancer-Experience-Registry.html" target="_blank">www.cancerexperienceregistry.org</a>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The researchers hope to use this information to improve the educational materials and the overall quality of care that cancer patients receive. </li> <li class="seamTextUnorderedListItem">This study is also enrolling people diagnosed with other types of cancer. </li> <li class="seamTextUnorderedListItem">The data collected from this study can be found <a href="https://www.cancersupportcommunity.org/RegistryIndexReport2017" target="_blank">here.</a></li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT02333604' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancerexperienceregistry.org/' target='_blank'>Cancer Support Community Study Website: Cancer Experience Registry</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancersupportcommunity.org/RegistryIndexReport2017' target='_blank'>Cancer Support Community: Cancer Experience Registry Index Report 2017</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.youtube.com/watch?v=SyyUYqyNaCc' target='_blank'>Cancer Support Community YouTube Channel: What is the Cancer Experience Registry?</a> </li></ul>
34
Registry to Use Artificial Intelligence to Improve Breast Cancer Screening
Elucidating the Impact of Social Wellness and Artificial Intelligence on the Psychological Consequences of Breast Cancer Imaging Scientific Title
Purpose
To use artificial intelligence (AI) to detect breast cancer earlier and more accurately.
Who is this for?
Anyone who has received a mammogram.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be asked to: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Upload mammogram images</li> <li class="seamTextUnorderedListItem">Use social platform (optional)</li> <li class="seamTextUnorderedListItem">Complete questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Breast cancer screening can cause stress and anxiety from false positive or unknown results.</li> <li class="seamTextUnorderedListItem">This UCF WEALTH platform is one of the first projects that allows patients to donate their breast cancer mammogram imaging results to reduce the mental challenges using social platforms and artificial intelligence.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06604078' target='_blank'>ClinicalTrials.gov</a> </li></ul>
35
Impact of Digital Exercise Coaching on Well-Being and Cost of Care for People with Stage I-IV Breast Cancer
A Decentralized, Double-blinded, Randomized, 18 Month, Parallel-group, Superiority Study to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalized Digital Application on Cancer Survivors' Cost of Care Scientific Title
Purpose
To study the ability of a personalized and interactive exercise program to reduce healthcare costs and improve health outcomes.
Who is this for?
People 21-64 years old with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have received treatment in the last year.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Live exercise coaching sessions using digital app, 3-5 sessions every week, 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Access to digital app about lifestyle modifications, 6 months</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">If you are in group 1, the sessions will focus on exercise and meditation with additional information on diet, sleep, and other lifestyle practices.</li> <li class="seamTextUnorderedListItem">If you are in group 2, the digital app includes expert guidelines on lifestyle modification focusing on exercise, meditation, as well as information on diet, sleep and other lifestyle practices.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06397651' target='_blank'>ClinicalTrials.gov</a> </li></ul>
36
Registry to Study the CTNNA1 Gene and Cancer Risk
CTNNA1 Familial Expansion (CAFÉ) Study Scientific Title
Purpose
To identify the cancer risks associated with inherited mutations and other changes in a gene called CTNNA1.
Who is this for?
People with mutations in the CTNNA1 gene, and people with family members who have mutations in the CTNNA1 gene.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will complete the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Online questionnaire about medical, genetic, and family history</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Mutations and other changes in a gene called CTNNA1 may be associated with inherited cancers, including gastric cancer, breast cancer, and other cancers.</li> <li class="seamTextUnorderedListItem">Better understanding of the relationship between CTNNA1 variations and breast cancer will be important for cancer risk management of individuals with these variations and their family members.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05126290' target='_blank'>ClinicalTrials.gov</a> </li></ul>
37
Therapy for Fatigue and Sleep Problems for Women with Stage I-III Breast Cancer
The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients Scientific Title
Purpose
To study the ability of therapy to reduce fatigue and sleep problems in women with breast cancer.
Who is this for?
Women with stage I, stage II, or stage III breast cancer who plan to receive, are receiving, or have received radiation. You must be experiencing fatigue and sleep problems.
Full eligibility criteria
Contact research site
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cognitive behavioral therapy (CBT), by telehealth, weekly for 1-3 months</li> <li class="seamTextUnorderedListItem">Sleep diary, daily</li> <li class="seamTextUnorderedListItem">Questionnaires, weekly</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Fatigue and sleep problems (insomnia) are common in people with cancer.</li> <li class="seamTextUnorderedListItem">Cognitive behavioral therapy (CBT) is a type of therapy that focuses on the relationship between thoughts, feelings, and behaviors.</li> <li class="seamTextUnorderedListItem">All therapy appointments will be held by telehealth (virtually).</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05226078' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.komen.org/breast-cancer/treatment/side-effects/fatigue-and-insomnia/#:~:text=Some%20treatments%20may%20cause%20fatigue,time%20%5B279%2D280%5D.' target='_blank'>Susan G. Komen: Fatigue and Insomnia</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mayoclinic.org/diseases-conditions/insomnia/in-depth/insomnia-treatment/art-20046677' target='_blank'>Mayo Clinic: Cognitive Behavioral Therapy (CBT) for Insomnia</a> </li></ul>
38
Questionnaires About Pain After Mastectomy and Breast Reconstruction
Persistent Postmastectomy Pain: Defining the Burden of Disease and the Role of Surgical Reinnervation in Patients With Breast Reconstruction Scientific Title
Purpose
To study how common long-term pain is after mastectomy and breast reconstruction.
Who is this for?
Women with stage 0 (DCIS), stage I, stage II, or stage III breast cancer or women with high risk of breast cancer who received a mastectomy and breast reconstruction surgery between 6 months and 15 years ago.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires about pain</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Pain may continue even after healing from surgery is complete.</li> <li class="seamTextUnorderedListItem">This study seeks to understand how long this pain lasts after surgery.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06627582' target='_blank'>ClinicalTrials.gov</a> </li></ul>
39
Integrative Medicine at Home Program for People With Stage I-IV Breast Cancer
Integrative Medicine for Patient-reported Outcomes, Values, and Experience (IMPROVE) Scientific Title
Purpose
To find out whether the Integrative Medicine at Home program can help reduce symptoms and improve treatment satisfaction.
Who is this for?
People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are currently receiving treatment.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Integrative Medicine at Home program, 3 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Enhanced Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Integrative medicine handout</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Integrative Medicine at Home program offers virtual (online rather than in-person) group classes focusing on mind-body practice.</li> <li class="seamTextUnorderedListItem">Mind-body practice is a health practice that combines mental focus, controlled breathing, and body movements to help relax the body and mind and reduce symptoms such as tiredness, pain, or insomnia.</li> <li class="seamTextUnorderedListItem">The classes will be led by an Integrative Medicine Service (IMS) clinical therapist using Zoom video conferencing platform.</li> <li class="seamTextUnorderedListItem">If you are in Group 2, you will be given a handout to encourage you to visit Memorial Sloan Kettering's Integrative Medicine website to access pre-recorded, on-demand meditation videos and audios.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05053230' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine' target='_blank'>Memorial Sloan Kettering Cancer Center: Integrative Medicine</a> </li></ul>
40
Saliva Samples and Questionnaires to Study How Genes Affect Breast Cancer Risk
The Rutgers University Genetics Coordinating Center Breast Cancer Study Scientific Title
Purpose
To study how genes impact breast cancer risk.
Who is this for?
People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer, and people who have not been diagnosed with breast cancer.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide saliva (spit) sample, by mail</li> <li class="seamTextUnorderedListItem">Questionnaires, online</li> <li class="seamTextUnorderedListItem">Access to your health records (optional)</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">By participating in this study, you will receive information about your genetic risk for free.</li> <li class="seamTextUnorderedListItem">Mutations in genes called BRCA1 and BRCA2 explain only about 25% of the genetic cause of breast cancer. </li> <li class="seamTextUnorderedListItem">Researchers are trying to learn more about the genetic cause of breast cancer, which will help researchers create new treatments and improve current treatment options.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06773897' target='_blank'>ClinicalTrials.gov</a> </li></ul>
41
Using Artificial Intelligence to Match Patients to Clinical Trials (SYNERGY-AI)
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry Scientific Title
Purpose
To study if a computer that has been taught how to match people to clinical trials (artificial intelligence) can help increase enrollment in clinical trials.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer who have already decided to enroll in a clinical trial.
Full eligibility criteria
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A clinical trial matching report based on your medical records that you can review with your doctor.</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This trial will use artificial intelligence and virtual tumor boards to help match people to clinical trials.</li> <li class="seamTextUnorderedListItem">The researchers will also create a registry to study the medical and financial effects of this program. </li> <li class="seamTextUnorderedListItem">This is an international trial that is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03452774' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://massivebio.com/' target='_blank'>Massive Bio Study Information Page</a> </li></ul>
42
MBC Connect Patient Registry: Sharing MBC History, Experiences, and Quality of Life
MBC Connect -- Patient Powered. Research Driven Scientific Title
Purpose
To collect information about the experiences of people with metastatic breast cancer for researchers and clinicians and to provide personalized information to each participant.
Who is this for?
People with metastatic (stage IV) breast cancer.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">You will be asked to fill out surveys about your breast cancer diagnosis, treatment history and quality of life.</li> <li class="seamTextUnorderedListItem">Based on information you enter, you will get personalized insights and alerts with MBC news, events, and clinical trial opportunities.</li> </ul> <p class="seamTextPara"> To join the registry, click here: <a href="https://www.mbcconnect.org/" target="_blank">www.mbcconnect.org/</a><p></p></p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MBC Connect is a free, web and mobile-friendly registry that collects information about the experiences of people with metastatic breast cancer. </li> <li class="seamTextUnorderedListItem">Joining the registry allows you to receive personalized information about MBC-related news, events, and clinical trial opportunities. </li> <li class="seamTextUnorderedListItem">Researchers and clinicians will be able to analyze information collected in the registry in research studies. </li> <li class="seamTextUnorderedListItem">MBC Connect is available in English and Spanish.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'><a href='https://www.mbcconnect.org/' target='_blank'>MBC Connect</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mbcalliance.org/' target='_blank'>Metastatic Breast Cancer Alliance</a> </li></ul>
43
RealRisks Online Program for Breast Cancer Risk Assessment
Integrating EHR and Patient-generated Health Data for Breast Cancer Risk Assessment and Decision Support in a Diverse Multiethnic Population Scientific Title
Purpose
To study how the RealRisks program promotes understanding of breast cancer risk and prevention and perceptions by users of their risk for breast cancer.
Who is this for?
Women, age 35-74 years old, at high risk for breast cancer but who have not been diagnosed with breast cancer.
Full eligibility criteria
Contact research site
Share with my doctor
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- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Use of the RealRisks program, online</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">RealRisks is a web-based patient-centered program designed to improve: 1) accurate understanding of breast cancer risk; 2) knowledge about drugs that could prevent breast cancer, and 3) making choices based on information. RealRisks includes audio and modules about breast cancer risk (including interactive games on risk communication) and drugs that could prevent breast cancer. </li> <li class="seamTextUnorderedListItem">Through RealRisks, study investigators will collect information on breast cancer risk factors to calculate a person's breast cancer risk score and also factors that influence decision-making about prevention. </li> <li class="seamTextUnorderedListItem">RealRisks generates an action plan for patients summarizing their personalized breast cancer risk and preference for prevention.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05810025' target='_blank'>ClinicalTrials.gov</a> </li></ul>
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No Travel Required
VISITS: Online forms, questionnaires, saliva sample by mail
PHASE: NA
NCT ID: NCT00000002
MBC Project: Collecting Information About Metastatic Breast Cancer To Further Research
The Metastatic Breast Cancer Project Scientific Title
Purpose
To accelerate research in treating, curing and preventing metastatic breast cancer.
Who is this for?
People with metastatic (stage IV) breast cancer.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> Your participation will include the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Complete a simple online form about yourself and your cancer</li> <li class="seamTextUnorderedListItem">Fill out an online consent form that gives your permission for the researchers to obtain copies of your medical records and some of your stored tumor tissue</li> <li class="seamTextUnorderedListItem">Provide a saliva sample and send back via U.S. mail </li> </ul> <p class="seamTextPara"> To learn more and/or to participate, click here: <a href="https://www.mbcproject.org/" target="_blank">https://www.mbcproject.org/</a><p></p></p>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The goal of the Metastatic Breast Cancer Project is to accelerate research in treating, curing and preventing metastatic breast cancer. </li> <li class="seamTextUnorderedListItem">If you take part in the project, you will fill out questionnaires, provide a saliva sample, and share a piece of your stored tumor tissue and copies of your medical records with the researchers. </li> <li class="seamTextUnorderedListItem">The researchers believe analyzing this data will help them learn more about metastatic breast cancer and make more research advances. </li> <li class="seamTextUnorderedListItem">The MBC Project was created by a coalition of researchers and breast cancer advocacy organizations.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'><a href='https://www.mbcproject.org/' target='_blank'>The Metastatic Breast Cancer Project</a> </li></ul>
45
Understanding the Experience of People with Advanced Breast Cancer Receiving Hospice Care
The COMPASSION Study: Applying Telehealth to Innovate and Strengthen Connections for Patients with Metastatic Breast Cancer Receiving Hospice Care Scientific Title
Purpose
To better understand the in-home hospice experience for people with advanced breast cancer and their caregivers.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer who live in Massachusetts and are planning to receive hospice care at home. Caregivers are also eligible to participate.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Telehealth appointments, by Zoom or phone, weekly for 1 month</li> <li class="seamTextUnorderedListItem">Survey, by email or phone</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care</li> <li class="seamTextUnorderedListItem">Survey, by email or phone</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Telehealth check-in appointments will be with your oncology care team (doctor, physician assistant, nurse practitioner, or hospice nurse) by Zoom or phone call.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06507930' target='_blank'>ClinicalTrials.gov</a> </li></ul>
46
Genetic Testing Educational Video for People with Stage I-IV Breast Cancer
Video Education With Result Dependent dIsclosure Scientific Title
Purpose
To study if an educational video improves knowledge of genetic testing for inherited cancer risk and could be used as an alternative to genetic counseling before genetic testing.
Who is this for?
People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have not received genetic testing.
Full eligibility criteria
Contact research site
Share with my doctor
Share with my patient
- What's involved?
- What's being studied?
- How can I learn more?
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<p class="seamTextPara"> You will be assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Watch educational video about genetic testing for inherited cancer risk</li> <li class="seamTextUnorderedListItem">Complete interview, by video or telephone</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times in 3 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Receive genetic counseling</li> <li class="seamTextUnorderedListItem">Questionnaires, 2 times in 3 weeks</li></ul>
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<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The video summarizes the core educational components of a genetic counseling visit.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>
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<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05225428' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/genomics/gtesting/genetic_testing.htm' target='_blank'>Centers for Disease Control and Prevention: Genetic Testing</a> </li></ul>
