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Young Survivors

Breast Cancer in Women Diagnosed Before Age 40

Identification of Novel Genetic Risk Factors That Contribute to the Risk for Breast Cancer (NCT00276120)

Summary

Breast cancer is the leading cause of cancer deaths in women 20-39 years of age. The goal of this trial is to identify the genetic factors that distinguish breast cancer in younger women compared to older women. The researchers hope that identifying these genetic factors will lead to new treatments for younger women who have been diagnosed with breast cancer or who are at high-risk for developing the disease. All women who were diagnosed with breast cancer at age 40 or younger (regardless of current age) are eligible to participate. Because all study-related materials will be mailed, participants can live anywhere in the U.S.

  • Participation TimeBlood sample and questionnaire by mail
  • No Visits Required for this TrialNo travel required 
What's Involved    Contact information

A Study of the Relationship Between Lifestyle Behaviors and Cognitive Function

Relationships Among Cognitive Function, Lifestyle, and Exercise After Cancer Treatment (NCT02523677)

Summary

Cancer and it treatment can cause problems with memory and other brain (cognitive) functions. Previous research in people without cancer suggests lifestyle behaviors, such as exercise and sleep, can affect cognitive function and quality of life. This study is investigating the relationship between lifestyle behaviors and brain function in breast cancer patients and survivors. To be eligible, a woman must have been diagnosed with breast cancer (it doesn't matter if treatment has started or been completed) and have access to an iPad, iPad Air, or iPad Mini and the Internet.

  • Participation Time2 online questionnaires and 2 cognitive tests over 6 months
  • No Visits Required for this TrialNo travel required 
What's Involved    Contact information: Call BCT at (415) 476-3793

Nutrition, Physical Activity & Brain Function in Breast Cancer Survivors & Healthy Women

Lifestyle Factors, Inflammation, and Cognition in Breast Cancer Survivors (NCT02591316)

Summary

This study is looking at physical activity, nutrition, body composition and brain function in breast cancer survivors and healthy women. Participants will wear an activity monitor to measure their physical activity level. To be eligible, women must be able to attend 2 testing sessions at Texas State University San Marcos with up to 1 month in between each session. Breast cancer survivors must have competed primary treatment (surgery, radiation and/or chemotherapy) within 5 years.

  • Participation Time2 visits over 1 month
  • Participating research sites
    Research sites:
    Call BCT: (415) 476-3793
What's Involved    Contact information: Call BCT at (415) 476-3793

Sexual and Reproductive Health Study

Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma (NCT01788839)

Summary

Cancer and its treatment may affect sexual and reproductive health. To help researchers learn more about the problems women face, participants in this study will complete questionnaires on sexuality and pregnancy before, during, and after cancer treatment. The information will be used to help doctors identify which women are most likely to have early menopause or develop sexual problems during cancer therapy, or have difficulty getting pregnant after cancer treatment. To be eligible for this study a woman must be age 50 or younger, newly diagnosed with breast cancer, and planning on having, or within one month of starting, chemotherapy.

What's Involved    Contact information

The Young Women's Breast Cancer Study

Helping Ourselves, Helping Others: The Young Women's Breast Cancer Study (NCT01468246)

Summary

Young women with breast cancer have unique needs and concerns. The goal of this study is to follow a large group of young women with breast cancer over time to learn more about the types of tumors they develop, the treatments they have, the side effects they experience, and the psychosocial concerns they face. The researchers are also interested in seeing if there is a relationship between tumor biology and patient outcome. To be eligible, participants must have been diagnosed with breast cancer at age 40 or younger.

What's Involved    Contact information

Measuring Breast Density in Premenopausal Breast Cancer Patients on Tamoxifen

Development of a Quantitative Tissue Optical Index of Breast Density (NCT01773551)

Summary

Some studies have suggested that premenopausal breast cancer patients whose breasts become less dense (as measured by a mammogram) while they are on tamoxifen are less likely to have a recurrence than women on tamoxifen whose breast density does not change. Researchers have developed a new tool called diffuse optical spectroscopic imaging that uses light to measure tissue thickness. This study is looking at whether this new tool can be used to measure changes in breast density. To be eligible, a woman must be premenopausal and taking tamoxifen to treat stage I - III breast cancer.

What's Involved    Contact information

Ovarian Function After DCIS and Breast Cancer

Predictors of Ovarian Insufficiency Through Serial Exams in Young Breast Cancer Patients (POISE Study) (NCT01197456)

Summary

Premenopausal women may face issues related to having children as they undergo breast cancer care, and these concerns may influence their treatment choices. Tools that can accurately predict how treatment may affect ovarian function could help women and their doctors make choices that take into account the potential impact on fertility. The goal of this study is to identify pre-chemotherapy hormonal, genetic, and ovarian imaging markers that can predict whether a woman's ovaries are likely to continue to function at the end of her cancer treatments. Participants will be followed from the time of diagnosis to five years after treatment.

What's Involved    Contact information

Immune System Response to Breast Cancer in Women Under Age 50

A Translational Study of the Interactions Between Prior Pregnancy and the Biologic Subtype of Breast Cancer in Defining the Cancer: Host Immunologic Interaction (NCT01503190)

Summary

Researchers are interested in learning more about the role the immune system plays in cancer. This study is looking specifically at the immune system in women with breast cancer who are under age 50. The researchers will look to see if differences in their immune system correspond to different types of tumors including tumors that develop during or after a pregnancy. The investigators may go on to use some of the breast cancer tissue collected in this study to create models that could be used to develop and test new drug treatments.

What's Involved    Contact information