Home   /  Find a Trial  /  See All TrialsHELP  /   AYUDA  /   求助 : help-desk@bctrials.org  /   (415) 476-5777Click to print page Print
 

See All Trials

QuickViews

Match by Tumor Type:

Newly Diagnosed (Stage I-III)
Biomarker status:
 Hormone-positive (ER+ and/or PR+)
 HER2-positive (HER2+)
 Triple negative (ER-/PR-/HER2-)
Inflammatory Breast Cancer
Biomarker status:
 Hormone-positive (ER+ and/or PR+)
 HER2-positive (HER2+)
 Triple negative (ER-/PR-/HER2-)

View by Trial Type:

Treatment:

 

Non-Treatment:

see All Trials

Sort by zip code:  

 

Share

Facebook
Twitter
Twitter

 
Support/Education

Reproductive Health Survivorship Care Plan for Young Survivors

Intervening on Reproductive Health in Young Breast Cancer Survivors (NCT02667626)

Summary

Young breast cancer survivors frequently have concerns about fertility, birth control, and sexual function. Researchers have developed a survivorship care plan for young survivors that addresses these reproductive health issues. This study is comparing the effectiveness of two different survivorship care plans for young survivors. As part of the study, participants will discuss reproductive health issues with the healthcare provider of their choice. To be eligible, a woman must have been diagnosed with breast cancer within the past five years and must have been age 45 or younger at the time of her diagnosis.
This is a Phase III trial

  • Participation Time3 online questionnaires over 6 months
  • No Visits Required for this TrialNo travel required 

Online-Based Decision Support for Metastatic Breast Cancer Patients

Four Conversations Randomized Controlled Trial (NCT02944344)

Summary

To take part in this study, you must have metastatic (stage IV) breast cancer. You must also have internet access through a computer, laptop, tablet or other mobile device. This study is looking at whether an online-based decision support program improves quality of care for metastatic breast cancer patients. The Four Conversations is an online-based decision support program designed to help patients with decision-making and care planning. It encourages patients to have four conversations: an informative conversation with healthcare professionals, a supportive conversation with family and friends, an inspirational conversation with or about spirituality, and an honest conversation with yourself.

  • Participation TimeOnline-based decision support and surveys over 2 months
  • No Visits Required for this TrialNo travel required 

Information About Mammography Screening for Women Age 75 and Older

Randomized Trial of a Mammography Decision Aid for Women Aged 75 and Older (NCT02198690)

Summary

It is not known whether the benefits of mammography screening outweigh the risks in women age 75 and older. To improve older women's understanding of the benefits and risks of mammography screening, researchers have developed a pamphlet that provides information about mammography specifically for this age group. This study is investigating whether the pamphlet improves older women's decision-making about mammography screening. To be eligible, women must be between the ages of 75 and 89.

Stress Management Program for Latina Survivors in Three Rural California Areas

Translating a Stress Management Program for Latinas (NCT02931552)

Summary

To take part in this study, you must identify as Latina and have been diagnosed with DCIS (ductal carcinoma in situ) or stage I-III breast cancer. You must also live in a rural area (Tulare, Santa Cruz or Imperial Valley County) in California, and be primarily Spanish-speaking, or Spanish monolingual. This study is investigating whether a community-based Stress Management Program called Nuevo Amanecer-II helps improve quality of life and reduce stress in Latinas living in rural areas in California. The stress management program is provided in-person by Compañeras (Companions), Latinas who have had breast cancer and have received training on ways to support others with breast cancer.

Using Telemedicine for Genetic Counseling for the BRCA1/2 Mutations

A Randomized Study Of TeleGenetics Versus Usual Care To Increase Access To Cancer Genetic Services (NCT02517554)

Summary

To take part, you must be at high risk for having the BRCA mutations that increase breast and ovarian cancer risk. You must also have insurance coverage for genetic testing. Telemedicine (telephone and videoconferencing) may provide a way to offer genetic counseling to women who do not have a genetic counselor in their area. This study will allow researchers to learn if using telemedicine to deliver genetic counseling works as well as in-person genetic counseling sessions.

An Internet Program to Improve Communication Between Doctors and Cancer Patients

PatientCareAnywhere: Patient Support and Empowerment Across the Care Continuum (NCT02408406)

Summary

To take part in this study, you must be getting treated for breast cancer at City of Hope Medical Center in California. You must also have internet access at home. PatientCareAnywhere is an interactive internet (online) program that was designed to help patients communicate better with their doctors during their cancer treatment. This study will allow researchers to see if the program works better than traditional printed education materials.

A Study of Inflammatory Markers, Chemotherapy and Chemobrain

Inflammation-Induced CNS Glutamate During Breast Cancer Treatment (NCT02421978)

Summary

Chemotherapy often causes cognitive symptoms (chemobrain) that can continue for months to years after treatment has ended. Inflammation caused by chemotherapy may contribute to these cognitive problems. In this study, researchers will measure the level of inflammatory markers in the blood and the brain of breast cancer patients receiving chemotherapy, breast cancer patients not receiving chemotherapy, and healthy volunteers to better understand the link between chemobrain and chemotherapy.

Clinical Pharmacists for Adults Age 65 and Older During Chemotherapy

Pilot Study of a Pharmacy Intervention for Older Adults With Cancer (NCT02871115)

Summary

To take part in this study, you must be age 65 or over and you must be planning to have your first chemotherapy treatment for your breast cancer at Massachusetts General Hospital. This study is looking at whether meeting with a clinical pharmacist during a chemotherapy session to discuss your history of medications and vaccinations improves your overall care. The group of patients who meet with the pharmacist will be compared with a group of patients who do not see a pharmacist as part of their routine care. This study also is enrolling patients with gastrointestinal and lung cancer.

Skills Workshop to Improve Memory & Thinking in Breast (and Other) Cancer Survivors

Behavioral and Neural Indices of Cognitive Rehabilitation in Women's Cancer: A Pilot Study (NCT01641068)

Summary

Thinking abilities, concentration, mood and quality of life can be affected by cancer and its treatments. This study is investigating the benefits of a memory and thinking skills workshop designed for breast and other cancer survivors. To be eligible for the study, survivors must have been treated with chemotherapy. Participants will be randomly assigned to either the skills workshop or a workshop on the brain and cognition. After the study is completed, the individuals who took part in the brain and cognition education workshop can take part in the memory and thinking skills workshop. To be eligible, participants must be able to attend a minimum of 3 testing sessions in Seattle, WA.

Comparing Two Types of Support Groups for Women with Metastatic Breast Cancer

Self-management Interventions for Pain in Advanced Breast Cancer (NCT01927081)

Summary

Studies have found that breast cancer patients often benefit from talking about their illness with other breast cancer patients. Support groups can foster these types of discussions. This study is comparing two different types of support groups for women with metastatic breast cancer. To be eligible, a woman must be receiving breast cancer care at the Duke Cancer Institute in Durham, North Carolina.

Improving Quality of Life Among Latina, Spanish-Speaking Breast Cancer Survivors

Developing an Intervention to Reduce Stress and Improve Quality of Life in Underserved Urban Latina Breast Cancer Survivors (NCT02521961)

Summary

Taking part in a support group may help Latina breast cancer survivors reduce distress and improve their health-related quality of life. This study is evaluating the effectiveness of a support group developed specifically for Latina breast cancer survivors. The group will address topics such as stress management and emotional coping strategies, nutrition and physical activity, sexuality and body image, medical advocacy and self-care, and social support. To be eligible, participants must be a Spanish-speaking Latina and a current resident of King, Snohomish, or Pierce counties in Washington State.

Sex & Intimacy Counseling for Stage I-III Breast (or Gynecologic) Cancer Survivors

Psychosexual Intervention for Gynecologic and Breast Cancer Patients (NCT01764802)

Summary

It is common for female breast and gynecologic cancer survivors to have concerns about sex and intimacy. Researchers think individual and/or group counseling can help survivors address these concerns. This study is comparing two different ways of providing support and counseling around sexual intimacy issues to female breast and gynecologic cancer survivors. To be eligible, participants must live less than 70 miles from the Ohio State University Medical Center.
This is a Phase II trial

Counseling to Enhance Intimacy in Couples Facing Breast Cancer

Pilot Study of an Intimacy Enhancement Intervention for Couples Facing Breast Cancer (NCT02721147)

Summary

Many breast cancer survivors have concerns about how their diagnosis will affect sex, intimacy, and quality of life. Researchers have developed a counseling program to enhance intimacy among couples facing breast cancer. Half of the women who enroll in this study will be enrolled in this new intimacy counseling program. The other half will receive educational materials through the mail. This will allow the researchers to see if the new intimacy program is more effective than the educational program at improving patient and partner sexual quality of life. It will also allow the researchers to evaluate the effect of the program on both the breast cancer survivor and her relationship. To be eligible, a woman must have completed breast cancer treatment for non-recurrent stage I-III breast cancer between 6 months to 5 years ago, have been living with a romantic partner for over 6 months, and be a patient at Fox Chase Cancer Center in Pennsylvania.

Integrative Therapy Program to Prevent Lymphedema after Surgery

Prevention of Secondary Lymphedema by Utilizing Self-management Education in Conjunction With Acupuncture Among Breast Cancer Patients Who Are at High Risk of Developing Lymphedema (NCT02528539)

Summary

Lymphedema is a painful swelling in the arm, hand, or wrist caused by a build-up of lymph fluid. Women whose breast cancer surgery includes removing lymph nodes under the arm that contain cancer cells--called an axillary lymph node dissection--are at increased risk of developing lymphedema. Researchers have developed an integrative therapy program for lymphedema that includes acupuncture along with education on the benefits of a healthy diet, exercise, and lymphatic drainage techniques women can do on their own. This study is evaluating the feasibility and effectiveness of using this integrative therapy program to reduce the risk of lymphedema after breast cancer surgery. To be eligible, women must be newly diagnosed with stage I-III breast cancer and have had an axillary lymph node dissection within 4-6 weeks prior to enrollment.

Study of Palliative and Cancer Care for Individuals with Metastatic Breast Cancer

A Collaborative Palliative and Oncology Care Model for Metastatic Breast Cancer (NCT02730858)

Summary

Palliative care is designed to decrease pain and other symptoms like fatigue. It also is designed to support individuals and their families as they cope with an illness. Palliative care is not the same as hospice care, which is focused on end-of-life care. Palliative care specialists are trained to help individuals with serious illnesses. This study is evaluating the impact of a collaborative palliative and cancer care model to a standard oncology care model that makes palliative care available when requested for individuals with metastatic breast cancer. To be eligible, participants must be receiving cancer care at Massachusetts General Hospital in Boston.

Helping Mothers Talk to Their Children About BRCA1/2 Testing

Parent Communication Study II - Randomized Controlled Trial of Decision Support vs. Education for Parent Communication of BRCA 1/2 Cancer Genetic Test Results to Children (NCT00685256)

Summary

Mothers who undergo BRCA testing often have questions about how and when to discuss genetic testing with their children. Researchers have developed a decision-making guide to help improve mother-child communication about BRCA testing. This study is investigating whether using this decision-making guide along with genetic counseling is better than genetic counseling alone in addressing the needs of mothers undergoing BRCA1/2 testing and their minor-age children.
This is a Phase III trial

An Online Stress Reduction Program for Young Breast Cancer Survivors & Their Partners

Couples-Based Mindfulness for Young Breast Cancer Survivors (NCT02840344)

Summary

To take part in this study, you must have been age 45 or younger at the time of your breast cancer diagnosis; you must have been diagnosed between one and six years ago; and you and your partner must have access to email and the internet. Researchers have developed an 8-week mindfulness-based stress reduction program to help young breast cancer survivors and their partners live healthier lives. This study will see whether the program helps improve you and your partner's well-being. Study participants will receive an Android tablet to access the program.

Increasing Mammography Screening Rates Among Korean-American Women in Minnesota

Mobile Phone Multimedia Messaging Intervention for Breast Cancer Screening: Intervention Phase (NCT01972048)

Summary

Korean-American women have one of the lowest breast cancer screening rates of U.S. American women. mMammogram is a mobile app that uses messages, video, audio, and emoticons to educate, promote, and reinforce breast cancer screening. This study is comparing the effectiveness of mMammogram to an educational brochure for increasing mammography screening rates among Korean-American women between the ages of 40 and 70. To be eligible, a woman must be Korean-American, have a phone that can receive text messages, and be living in Minnesota.

An Internet-based Support Program for Women with Metastatic Breast Cancer

Project Connect: Enhancing Connections During Metastatic Breast Cancer (PCO) (NCT02866994)

Summary

To take part in this study, you must have stage IV, metastatic breast cancer, and reside in greater Los Angeles area in California. This study is investigating whether women with metastatic breast cancer benefit psychologically or physically from creating a personal website they can use to write about their breast cancer experience and share with friends, family members and other women diagnosed with breast cancer.

Vitamin D to Treat Anti-Estrogen Therapy Side Effects in Women with Stage IV Breast Cancer

Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D) (NCT02186015)

Summary

Anti-estrogen therapies are used to treat ER+ and/or PR+ breast cancer. Side effects of these therapies include pain, fatigue, mood and sleep disturbances. Researchers think that vitamin D supplements may help reduce these side effects. However, vitamin D can also lead to excess calcium in the blood, which could increase estrogen production in the body. This study will monitor blood calcium and vitamin D levels to identify the best dose and effectiveness of a vitamin D supplement for reducing anti-estrogen related side effects in women with metastatic breast cancer.
This is a Phase I trial

A Program to Reduce the Number of Hours Breast Cancer Survivors Spend Sitting Down

Randomized Controlled Trial of Sitting Time Interventions in Breast Cancer Survivors (NCT02510430)

Summary

To take part in this study, you must have been treated for DCIS or stage I, II or III breast cancer and typically spend 8 or more hours a day sitting down. You must also use the internet on a regular basis. And you must be able to attend 3 study visits at the University of Wisconsin in Madison. Previous studies suggest that spending many hours a day sitting down is associated with an increased cancer risk. This study will test different strategies for helping you modify the amount of time you spend sitting down.

Nutrition Education and Acupuncture for Weight Loss After Chemotherapy

Comparison of Weight Loss Among Early Stage Breast Cancer Patients Post Chemotherapy: Nutrition Education in Combination With Weight Loss Acupuncture Vs. Nutrition Education Alone (NCT02081612)

Summary

Studies have found that women with breast cancer who are overweight or who gain weight after their diagnosis are at increased risk of having a cancer recurrence. Acupuncture uses hair-thin needles to stimulate energy in the body. Acupuncture may help improve short and long-term weight loss among breast cancer survivors who have been treated with chemotherapy. This study is investigating whether using acupuncture along with a nutrition education program is better than using a nutrition education program alone in helping breast cancer survivors lose weight. To be eligible, participants must have completed breast cancer treatment and have a body mass index (BMI) of 30 or greater.

Educating Latinas About BRCA Mutations and Inherited Cancer Risk

Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer: Using Mental Models to Develop Culturally Targeted Media (NCT03075540)

Summary

To take part in this study, you must have a personal or family cancer history that makes your doctor think you are at high risk for having inherited a BRCA1 or BRCA2 genetic mutation. You must also identify as Latina. Mutations in the BRCA genes increase the risk of breast cancer. These mutations are inherited--they are passed down genetically through families by mothers and fathers. This study is evaluating whether a new educational video for Latinas about hereditary breast cancer, risk assessment, and genetic testing is an effective teaching tool.

Decision Aid for Women Age 70 and Older Diagnosed with ER+, HER2- Stage I-II Breast Cancer

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older (NCT02823262)

Summary

To take part in this study, you must be age 70 or older and have been diagnosed with ER+, HER2- breast cancer. In addition, your tumor must be stage I or stage II. This study is evaluating a breast cancer treatment Decision Aid created specifically for newly diagnosed older women. There are two phases to this study. In phase I, the researchers will collect feedback about the Decision Aid from breast cancer patients age 70 and over who were treated at least six months ago and their family members and clinicians. The researchers will use this feedback to improve the Decision Aid. In Phase II, the researchers will see if the revised Decision Aid helps women age 70 and older who have been diagnosed with ER+, HER2- stage I-II breast cancer make treatment decisions.

A Positive Piggy Bank: A Mindfulness Program for Women Scheduled for Breast Cancer Surgery

A Pilot Study of a Brief Pre-Operative Intervention for Patients Undergoing Breast Surgery (NCT02939040)

Summary

To take part in this study, you must be scheduled to have surgery for stage I, II, or III breast cancer. The goal of this study is to determine if participating in a mindfulness program called "Positive Piggy Bank" improves well-being and reduces post-surgery symptoms. If you take part in the "Positive Piggy Bank" program, you will note at least one positive event that happens each day, write it down on a piece of paper, and deposit the piece of paper in a piggy bank. You will read all the notes in the piggy bank the night before your surgery.

A Culturally Sensitive Social Support Program for Chinese-Speaking Survivors

A Culturally Sensitive Social Support Intervention (NCT02946697)

Summary

To take part in this study, you must speak Chinese (Mandarin or Cantonese) and have been treated for DCIS or stage I, II, or III breast cancer within the last 3 years. You must also live in or near Los Angeles, California. This study is looking at whether a social support program can help improve the quality of life of Chinese-speaking breast cancer survivors living in or near Los Angeles, California. The program will address topics including treatment-related side effects, symptoms of cancer recurrence, physical therapy and other complementary treatments, stress, depression and other emotional problems, communicating with family members, and body image. Each study participant will have the opportunity to establish a relationship with a peer-mentor who is also a Chinese-speaking breast cancer survivor.

Diet & Exercise Program for Overweight Women After Treatment For Stage I-III Breast Cancer

PANCREATIC NUTRITIONAL PROGRAM (PNP): A Novel Weight Reduction Program in Overweight/Obese Breast Cancer Survivors (NCT02432950)

Summary

To take part in this study, you must be a breast cancer survivor and be overweight (body mass index of 25-33). The pancreas helps turn the food you eat into fuel for your body. The pancreatic diet and lifestyle program helps protect the pancreas by keeping blood sugar levels low. Studies have found that women who are overweight are more likely to have their breast cancer come back. Researchers want to see whether a 12-week pancreatic diet and lifestyle program helps overweight survivors lose weight. The researchers will also investigate whether the diet and lifestyle program improves health and quality of life.

Exercise & Weight Management for People at High Risk for Triple-Negative Breast Cancer

Pilot Tests to Optimize the Delivery of Energy Balance Interventions (NCT02194387)

Summary

Previous studies have suggested that risk for triple-negative breast cancer (TNBC) is higher in people who are overweight and not physically active. Researchers are trying to determine what types of programs can help people lose weight and exercise more. Fitbit® is a small, wearable physical activity tracker that is designed to help with exercise and weight management. Telephone coaching, text messages, social networking, and self-monitoring can also help people trying to exercise more and lose weight. This study is looking at which combination of coaching, texting, and social networking is most effective in helping women at high-risk for breast cancer exercise more and lose weight. To be eligible, participants must have a BMI ≥25. They must also know they carry a BRCA mutation or be a family member of a breast cancer survivor.

Web-Based Weight Loss Program for African American Breast Cancer Survivors

Virtual Weight Loss Program for African-American Breast Cancer Survivors (NCT02699983)

Summary

SparkPeople is a free web-based, weight-loss program. It provides educational materials along with the social support that can help encourage women to to eat well and exercise. This study is looking at whether the SparkPeople program can help African-American breast cancer survivors maintain a healthy diet. To take part, you must identify as an African-American woman and have a BMI ≥ 30. It must be at least two years since your breast cancer diagnosis. You must have access to the internet or a smartphone, and must reside in New Jersey to participate.

Promoting Exercise to Enhance Well-Being in Breast Cancer Survivors

Peers Promoting Exercise Adoption and Maintenance Among Cancer Survivors (NCT02694640)

Summary

Exercise can be beneficial for women who have been treated for breast cancer. Studies have shown that exercise adoption among cancer survivors can improve their quality of life, mood, and fatigue. In this study, community volunteers from the American Cancer Society Reach to Recovery® program will be trained to talk with other breast cancer survivors and encourage them to exercise regularly. The study will evaluate the effects of three exercise maintenance programs on fatigue, mood, quality of life and physical functioning. Survivors diagnosed with breast cancer in the past 5 years are eligible to participate in this study.

Pink Warrior—Support Group Toolkit for Breast Cancer Survivors

Pink Warrior—Support Group Toolkit for Breast Cancer Survivors (NCT02750241)

Summary

To take part in this study, you must have been diagnosed with breast cancer within the last 6 months. You must also be able to go to the University of Texas Medical Branch Breast Health Clinic in Galveston. Pink Warrior is a physical activity program that was developed to help breast cancer survivors be more physically active. This study is looking at whether taking part in a weekly support group with a video game-based physical activity benefits breast cancer survivors.

Lifestyle Changes During Radiation Therapy to Improve Outcomes

The Role of Lifestyle Factors in Breast Cancer-Related Outcomes (NCT02079662)

Summary

Researchers are studying the effects that lifestyle has on the risk of a breast cancer recurrence, quality of life, physical functioning, hormone levels and immune function. This study is looking at the effect that a comprehensive lifestyle change program that addresses diet, exercise, and stress has on women with stage III breast cancer who are scheduled to have a 4 to 6-week course of radiation. To be eligible patients must have a body mass index (BMI) of 25 or higher. They must also not eat more than 3 servings of fruits/vegetables a day or exercise more than 75 minutes per week.

An Exercise Study for Older African-American and White Breast Cancer Survivors

A Physical Activity Intervention to Reduce Functional Health Disparities Among Older Breast Cancer Survivors (NCT02763228)

Summary

To take part in this study, you must have been treated for stage I, II, or III breast cancer within the last 5 years. You must also identify as non-Hispanic White or African-American and be age 65 or older. This study is investigating whether older breast cancer survivors who take part in an exercise program offered in their community have improved quality of life. The researchers also want to see if there are differences in how African-American and White breast cancer survivors respond to the exercise program.

A Supportive Program for Women with Metastatic Breast Cancer

A Trial to Strengthen Existential Resiliency Among Women With Metastatic Breast Cancer (NCT02707510)

Summary

The purpose of this study is to assess the impact of the Growing Resiliency and Courage (GRACE) program on spiritual and psychological well-being in women with metastatic breast cancer (breast cancer that has spread to other parts of the body). GRACE is a six-week, clinical program that covers topics such as hope, meaning, purpose, gratitude, strength, courage, perseverance, connectivity, humor and blessings. Each class lasts two hours; researchers will measure spiritual and psychological well-being with surveys.

Weight Loss Program to Prevent Recurrence in Women with HER2-, Stage II-III Breast Cancer

Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women With Early Breast Cancer (BWEL Study) (NCT02750826)

Summary

To take part in this study, you must have HER2-negative, early stage (stage II-III) breast cancer and be overweight or obese (BMI ≥27). It must also be 12 months or less since you were diagnosed with breast cancer. If you are overweight or obese at the time of your breast cancer diagnosis, you have a greater risk of having your cancer come back (recur) than do women who are not overweight or obese. This study is investigating whether overweight or obese women who take part in a weight loss program after being diagnosed with breast cancer are less likely to have their cancer come back than those who do not take part in the weight loss program.
This is a Phase III trial

Pain Coping Program for Managing Pain After Surgery in DCIS/Stage I-III Breast Cancer

Targeted Pain Coping Skills Training (PCST) for Prevention and Treatment of Persistent Post-Mastectomy Pain (NCT02439437)

Summary

Researchers have developed a Targeted Pain Coping Skills Training program women can take part in over the phone that may help reduce pain and stress after a mastectomy. This study is comparing this new phone-based skills training program to a program that gives patients printed educational materials. To take part, you must have ductal carcinoma in situ (DCIS) or stage I-III breast cancer, had breast surgery within the last 6 weeks, and have had a pain score of 3 or more during the first month following your breast cancer surgery. To be eligible, participants must receive cancer treatment in the Duke Health System.

Counseling for Breast Cancer Patients Age 70 and Over

Pilot of a Geriatric Group Psychoeducational Intervention for Elderly Patients With Cancer (NCT00984321)

Summary

Many women seek counseling after a breast cancer diagnosis. This counseling program was developed to meet the specific needs of older cancer patients, who often find themselves facing problems related to both cancer and aging. The goal of this trial is to see whether a counseling program can help reduce depression, anxiety, and feelings of loneliness and isolation as well as improve the quality of life of older women with breast cancer. To be eligible, participants must be receiving treatment at Memorial Sloan-Kettering Cancer Center.

Hypnosis for Reducing Pain Associated With Aromatase Inhibitors

Hypnosis to Reduce Aromatase Inhibitor (AI) Associated Musculoskeletal Pain and to Improve AI Adherence: An RCT to Explore Efficacy and Cost Effects (NCT02657993)

Summary

Aromatase inhibitors are used to treat hormone-sensitive breast cancer in postmenopausal women. Muscle pain, joint pain and decreased grip strength are some of the most common side effects of these medications. These side effects can reduce quality of life and lead women to stop taking their aromatase inhibitors. Hypnosis is a mind-body intervention that has been shown to reduce pain. In this study, researchers will evaluate the feasibility of using hypnosis to reduce aromatase inhibitor-related pain and compare the effectiveness of hypnosis to empathetic listening for pain reduction. To be eligible, a patient must be currently taking an aromatase inhibitor (anastrozole, letrozole, or exemestane; have taken an aromatase inhibitor for at least three months; have at least two years of treatment remaining; and have ongoing pain and/or stiffness in one or more joints that began or worsened after starting on an aromatase inhibitor.

Mindfulness Meditation & Survivorship Education After DCIS & Stage I-III Breast Cancer

Improving Outcomes for Younger Breast Cancer Survivors: A Phase III Randomized Trial Targeting Behavioral Symptoms in Younger Breast Cancer Survivors (NCT03025139)

Summary

To take part in this study, you must be have been diagnosed with DCIS or stage I, II, or III breast cancer within the last five years. Your diagnosis must have occurred when you were age 45 or younger. You must also show symptoms of depression on the study's screening questionnaire. This study is comparing the benefits of mindfulness meditation and survivorship education for reducing symptoms of depression in women who were diagnosed with DCIS or stage I, II or III breast cancer before age 45. Mindfulness meditation may help you change the way you respond to thoughts and life events. Survivorship education tailored to younger survivors may help help reduce stress and improve well-being and quality of life.

Health Education for Reducing Chemotherapy-Related Weight Gain

Taking Health Realization Into Valued Eating and Exercise (THRIVE): A Feasibility Study of an Intervention to Prevent Weight Gain for Breast Cancer Survivors During Chemotherapy (NCT01941784)

Summary

Weight gain is a common side effect of chemotherapy treatment. The average patient gains about 5-8 pounds over a year. THRIVE (Taking Health Realization Into Valued Eating and Exercise) is a health education program that may help reduce weight gain and improve the quality of life of women undergoing chemotherapy. The goal of this study is to determine the effectiveness of the THRIVE project for preventing weight gain associated with chemotherapy treatments in women with newly diagnosed stage I-IV breast cancer who have recently started or are schedule to receive chemotherapy.

Self-Care Toolkit for Managing Side Effects After Surgery

Evaluation of a Self-Care Toolkit in Surgical Breast Cancer Patients (NCT02387320)

Summary

Side-effects associated with breast cancer surgery can include pain, anxiety, nausea, fatigue, and sleep disturbance. Researchers have developed a self-care toolkit to help women learn about mind-body skills and tools that can help them cope with these side effects. This study will compare the effectiveness of this kit to the standard of care for helping women reduce these side effects. To be eligible, a woman must be newly diagnosed with breast cancer and be receiving treatment at the San Antonio Military Medical Center Oncology Clinic.

A Program to Reduce Insomnia (Trouble Sleeping) Caused by Cancer or its Treatment

Brief Behavioral Intervention for Insomnia During Chemotherapy (NCT02165839)

Summary

Many women report that they experience insomnia--trouble sleeping--during their breast cancer treatment. A behavioral therapy program may help breast cancer patients cope with their insomnia. This study will compare a behavioral therapy program for insomnia to a healthy eating program in women being treated with chemotherapy or a biological therapy, like Herceptin, for early-stage breast cancer. To be eligible, a woman must have insomnia that began or got worse when she was diagnosed with cancer or began systemic treatment with chemotherapy or biological therapy.