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Individualized Radiotherapy Education for Patients with Stage I-III Breast Cancer

Impact of Individualized Radiotherapy Plan Review in Patients Receiving Adjuvant Radiotherapy for Breast Cancer (NCT02366806)


The standard of care for treating early-stage breast cancer is a lumpectomy followed by radiation. Prior to starting radiation, patients typically receive general information about radiation therapy and its potential side effects. An in-depth, personalized treatment education plan may be more beneficial. This study will compare the benefits of a standard radiation education plan to a personalized radiation education plan in patients with early-stage breast cancer. To be eligible, a patient must be scheduled to receive radiation therapy for early-stage breast cancer at the University of California, Davis.

Supportive Care for Patients with Metastatic Breast (and Other) Cancer

St. Judes-Stanford Comprehensive Support Initiative (NCT03154190)


To take part in this study, you must be newly diagnosed with metastatic (stage IV) breast cancer. This study is looking at whether supportive care provided by a health care coach is better than standard support for helping patients make treatment decisions that take into account their concerns about symptom management. Health care coaches are trained to talk to and educate cancer patients and their family members about care goals and shared decision making.

  • Participation TimeSession before and after oncology appointment; then weekly to monthly sessions, ongoing
  • Participating research sites
    Research sites: 1 site total

Pain Coping Program for Managing Pain After Surgery in DCIS/Stage I-III Breast Cancer

Targeted Pain Coping Skills Training (PCST) for Prevention and Treatment of Persistent Post-Mastectomy Pain (NCT02439437)


Researchers have developed a Targeted Pain Coping Skills Training program women can take part in over the phone that may help reduce pain and stress after a mastectomy. This study is comparing this new phone-based skills training program to a program that gives patients printed educational materials. To take part, you must have ductal carcinoma in situ (DCIS) or stage I-III breast cancer, had breast surgery within the last 6 weeks, and have had a pain score of 3 or more during the first month following your breast cancer surgery. To be eligible, participants must receive cancer treatment in the Duke Health System.

Counseling for Breast Cancer Patients Age 70 and Over

Pilot of a Geriatric Group Psychoeducational Intervention for Elderly Patients With Cancer (NCT00984321)


Many women seek counseling after a breast cancer diagnosis. This counseling program was developed to meet the specific needs of older cancer patients, who often find themselves facing problems related to both cancer and aging. The goal of this trial is to see whether a counseling program can help reduce depression, anxiety, and feelings of loneliness and isolation as well as improve the quality of life of older women with breast cancer. To be eligible, participants must be receiving treatment at Memorial Sloan-Kettering Cancer Center.

Educating Latinas About BRCA Mutations and Inherited Cancer Risk

Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer: Using Mental Models to Develop Culturally Targeted Media (NCT03075540)


To take part in this study, you must have a personal or family cancer history that makes your doctor think you are at high risk for having inherited a BRCA1 or BRCA2 genetic mutation. You must also identify as Latina. Mutations in the BRCA genes increase the risk of breast cancer. These mutations are inherited--they are passed down genetically through families by mothers and fathers. This study is evaluating whether a new educational video for Latinas about hereditary breast cancer, risk assessment, and genetic testing is an effective teaching tool.

Hypnosis for Reducing Pain Associated With Aromatase Inhibitors

Hypnosis to Reduce Aromatase Inhibitor (AI) Associated Musculoskeletal Pain and to Improve AI Adherence: An RCT to Explore Efficacy and Cost Effects (NCT02657993)


Aromatase inhibitors are used to treat hormone-sensitive breast cancer in postmenopausal women. Muscle pain, joint pain and decreased grip strength are some of the most common side effects of these medications. These side effects can reduce quality of life and lead women to stop taking their aromatase inhibitors. Hypnosis is a mind-body intervention that has been shown to reduce pain. In this study, researchers will evaluate the feasibility of using hypnosis to reduce aromatase inhibitor-related pain and compare the effectiveness of hypnosis to empathetic listening for pain reduction. To be eligible, a patient must be currently taking an aromatase inhibitor (anastrozole, letrozole, or exemestane; have taken an aromatase inhibitor for at least three months; have at least two years of treatment remaining; and have ongoing pain and/or stiffness in one or more joints that began or worsened after starting on an aromatase inhibitor.

A Culturally Sensitive Social Support Program for Chinese-Speaking Survivors

A Culturally Sensitive Social Support Intervention (NCT02946697)


To take part in this study, you must speak Chinese (Mandarin or Cantonese) and have been treated for DCIS or stage I, II, or III breast cancer within the last 3 years. You must also live in or near Los Angeles, California. This study is looking at whether a social support program can help improve the quality of life of Chinese-speaking breast cancer survivors living in or near Los Angeles, California. The program will address topics including treatment-related side effects, symptoms of cancer recurrence, physical therapy and other complementary treatments, stress, depression and other emotional problems, communicating with family members, and body image. Each study participant will have the opportunity to establish a relationship with a peer-mentor who is also a Chinese-speaking breast cancer survivor.

Ketogenic Diet and Taxol for Metastatic Breast Cancer

Ketogenic Diet and Chemotherapy to Affect Recurrence of Breast Cancer (The KETO-CARE Study)(NCT03535701)


To take part in this study you must have metastatic (stage IV) breast cancer.

This study is investigating whether a ketogenic diet helps the chemotherapy drug paclitaxel (Taxol®) control tumor growth. A ketogenic diet is a low-carbohydrate diet. Eating fewer carbohydrates forces the body to burn stored fat. Laboratory studies suggest being on a ketogenic diet may reduce inflammation and help chemotherapy drugs control tumor growth. Taxol is a chemotherapy drug routinely used to treat breast cancer.

Computer and Internet-Based Support Program for Asian-American Breast Cancer Survivors

To Enhance Breast Cancer Survivorship of Asian Americans (NCT02803593)


To take part in this study, you must have been diagnosed with breast cancer within the past 5 years and must self-identify as Chinese, Korean, or Japanese. You must also have access to the internet through a computer or mobile device (smartphone or tablet). This study will evaluate whether an internet and computer-based information and coaching/support program designed specifically for Asian-American breast cancer survivors improves quality of life. The program is provided in English, Mandarin Chinese, Korean, and Japanese.

An Internet Program to Improve Communication Between Doctors and Cancer Patients

PatientCareAnywhere: Patient Support and Empowerment Across the Care Continuum (NCT02408406)


To take part in this study, you must be getting treated for breast cancer at City of Hope Medical Center in California. You must also have internet access at home. PatientCareAnywhere is an interactive internet (online) program that was designed to help patients communicate better with their doctors during their cancer treatment. This study will allow researchers to see if the program works better than traditional printed education materials.

Treatment Adherence for Stage I-III Breast Cancer Patients Taking an Anti-Estrogen Drug

Improving Well-Being for Breast Cancer Patients Taking Adjuvant Endocrine Therapy (NCT02707471)


To take part in this study, you must have hormone receptor-positive (ER+/PR+) stage I-III breast cancer. You must also have a treatment plan that includes an anti-estrogen drug after surgery. This study is investigating which type of phone counseling session helps breast cancer patients continue to take their anti-estrogen drugs daily. If you take part, you will receive a smart medication bottle that records the time you take your drug and sends this information to the research team.

Decision Aid for Women Age 70 and Older Diagnosed with ER+, HER2- Stage I-II Breast Cancer

A Breast Cancer Treatment Decision Aid for Women Aged 70 and Older (NCT02823262)


To take part in this study, you must be age 70 or older and have been diagnosed with ER+, HER2- breast cancer. In addition, your tumor must be stage I or stage II. This study is evaluating a breast cancer treatment Decision Aid created specifically for newly diagnosed older women. There are two phases to this study. In phase I, the researchers will collect feedback about the Decision Aid from breast cancer patients age 70 and over who were treated at least six months ago and their family members and clinicians. The researchers will use this feedback to improve the Decision Aid. In Phase II, the researchers will see if the revised Decision Aid helps women age 70 and older who have been diagnosed with ER+, HER2- stage I-II breast cancer make treatment decisions.

Mindfulness Meditation & Survivorship Education After DCIS & Stage I-III Breast Cancer

Improving Outcomes for Younger Breast Cancer Survivors: A Phase III Randomized Trial Targeting Behavioral Symptoms in Younger Breast Cancer Survivors (Pathways to Wellness) (NCT03025139)


To take part in this study, you must be have been diagnosed with DCIS or stage I, II, or III breast cancer within the last five years. Your diagnosis must have occurred when you were age 45 or younger. You must also show symptoms of depression on the study's screening questionnaire. This study is comparing the benefits of mindfulness meditation and survivorship education for reducing symptoms of depression in women who were diagnosed with DCIS or stage I, II or III breast cancer before age 45. Mindfulness meditation may help you change the way you respond to thoughts and life events. Survivorship education tailored to younger survivors may help help reduce stress and improve well-being and quality of life.

Weight Loss Program to Prevent Recurrence in Women with HER2-, Stage II-III Breast Cancer

Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women With Early Breast Cancer (BWEL Study) (NCT02750826)


To take part in this study, you must have HER2-negative, early stage (stage II-III) breast cancer and be overweight or obese (BMI ≥27). It must also be 12 months or less since you were diagnosed with breast cancer. If you are overweight or obese at the time of your breast cancer diagnosis, you have a greater risk of having your cancer come back (recur) than do women who are not overweight or obese. This study is investigating whether overweight or obese women who take part in a weight loss program after being diagnosed with breast cancer are less likely to have their cancer come back than those who do not take part in the weight loss program.

This is a Phase III trial

An Exercise Study for Older African-American and White Breast Cancer Survivors

A Physical Activity Intervention to Reduce Functional Health Disparities Among Older Breast Cancer Survivors (NCT02763228)


To take part in this study, you must have been treated for stage I, II, or III breast cancer within the last 5 years. You must also identify as non-Hispanic White or African-American and be age 65 or older. This study is investigating whether older breast cancer survivors who take part in an exercise program offered in their community have improved quality of life. The researchers also want to see if there are differences in how African-American and White breast cancer survivors respond to the exercise program.

A Stress-Reduction Program for Women Getting Chemo Before Breast Cancer Surgery

An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer: A Randomized Pilot Study (NCT03429907)


To take part in this study, you must have early stage (stage I-III) breast cancer and be scheduled to have chemotherapy before surgery (neoadjuvant treatment). The AC chemotherapy--doxorubicin (Adriamycin®) plus cyclophosphamide (Cytoxan®)--must be followed by or preceded by paclitaxel (Taxol®), and given at MD Anderson Cancer Center in Texas. This study is looking at whether patients who use a mind-body stress-reduction app for two weeks before starting neoadjuvant chemotherapy have lower stress, better mood, and fewer physical symptoms during treatment than patients who do not take part int his program.

An Internet-based Support Program for Women with Metastatic Breast Cancer

Project Connect: Enhancing Connections During Metastatic Breast Cancer (PCO) (NCT02866994)


To take part in this study, you must have stage IV, metastatic breast cancer, and reside in greater Los Angeles area in California. This study is investigating whether women with metastatic breast cancer benefit psychologically or physically from creating a personal website they can use to write about their breast cancer experience and share with friends, family members and other women diagnosed with breast cancer.

Pink Warrior—Support Group Toolkit for Breast Cancer Survivors

Pink Warrior—Support Group Toolkit for Breast Cancer Survivors (NCT02750241)


To take part in this study, you must have been diagnosed with breast cancer within the last 6 months. You must also be able to go to the University of Texas Medical Branch Breast Health Clinic in Galveston. Pink Warrior is a physical activity program that was developed to help breast cancer survivors be more physically active. This study is looking at whether taking part in a weekly support group with a video game-based physical activity benefits breast cancer survivors.

Promoting Activity in Cancer Survivors

Promoting Activity in Cancer Survivors (NCT03060941)


To take part in this study, you must be a breast cancer survivor who completed treatment at least 3 months and no more than 5 years ago. You must also currently take part in less than 2.5 hours of moderate-to-vigorous physical activity a week. This study, called Promoting Activity Among Cancer Survivors (PACES), is investigating which methods are best for promoting physical activity among breast cancer survivors. The following methods are being tested in this study: print-based education materials, self-monitoring, counseling sessions, supervised exercise sessions, and access to a local exercise facility. Participants will be given a Fitbit®, a small, wearable physical activity tracker that is designed to help with exercise and weight management.

Telephone Support to Reduce Fatigue for Metastatic Breast Cancer Patients

Telephone Support for Metastatic Breast Cancer Patients (NCT03998618)


To take part in this study you must be a woman with stage IV metastatic breast cancer who is being treated at the Indiana University (IU) Simon Cancer Center, Eskenazi Health, IU Health North, IU Health Bloomington, IU Health Ball Memorial, Franciscan Health, or St. Vincent Health.

This study is evaluating whether a telephone-based psychotherapy program can reduce fatigue and improve activity level, mood, and cognition. The type of psychotherapy being studied is called Acceptance and Commitment Therapy (ACT). It teaches mindfulness exercises as well as ways to identify and engage in activities consistent with your personal values.

This is a Phase II trial