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1

RE104 for People with Stage 0-IV Breast Cancer and Adjustment Disorder With <span class="highlight">Anxiety</span> and Depression

A Randomized, Double-Blind, Parallel-Group, Dose-Controlled Study Evaluating the Safety and Efficacy of RE104 for Injection in the Treatment of Adjustment Disorder in Patients With Cancer and Other Medical Illnesses

Purpose: To study the safety and effects (good and bad) of RE104 for Injection to reduce depression and/or <span class="highlight">anxiety.</span>

Who is this for?: People with stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer with adjustment disorder that includes depression and/or <span class="highlight">anxiety</span> that has lasted for at least 1 month. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: High Dose</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">High dose of RE104, by injection</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Low Dose</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Low dose of RE104, by injection</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">RE104 is a psilocybin-like compound that may help with depression.</li> <li class="seamTextUnorderedListItem">This trial is enrolling people with other types of cancer and other serious diseases.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07002034' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://reunionneuro.com/programs/#approach' target='_blank'>Reunion Neuroscience: RE104</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.rekindlestudies.com/' target='_blank'>Reunion Neuroscience: REKINDLE Study Information</a> </li></ul>
1

RE104 for People with Stage 0-IV Breast Cancer and Adjustment Disorder With <span class="highlight">Anxiety</span> and Depression

A Randomized, Double-Blind, Parallel-Group, Dose-Controlled Study Evaluating the Safety and Efficacy of RE104 for Injection in the Treatment of Adjustment Disorder in Patients With Cancer and Other Medical Illnesses
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Nearest Location from 94108:
51 miles
Providence Medical Foundation
Santa Rosa, CA

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Visits:
9 visits within 2.5 months

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ClinicalTrials.gov: NCT07002034

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Phase II

2

Guided Meditation During Radiation for People with Brain Metastases

An Interventional Trial Using Guided Meditation During Radiation Therapy for Brain Tumors (Med-RT)

Purpose: To study the ability of guided meditation to decrease <span class="highlight">anxiety.</span>

Who is this for?: People with metastatic (stage IV) breast cancer that has spread to the brain (brain metastasis) who are planning to receive radiation to the brain. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Guided meditation during radiation sessions, 2 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Usual care</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The guided meditation practice involves a series of 5 audio recordings with the following topics: body scan, mindful breathing, mindfulness of discomfort, savoring memories, and loving-kindness.</li> <li class="seamTextUnorderedListItem">Each audio recording is 5 minutes.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06165653' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://mbcbrainmets.org/' target='_blank'>MBCBrainMets.org</a> </li></ul>
2

Guided Meditation During Radiation for People with Brain Metastases

An Interventional Trial Using Guided Meditation During Radiation Therapy for Brain Tumors (Med-RT)
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Nearest Location from 94108:
602 miles
Huntsman Cancer Institute
Salt Lake City, UT

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Visits:
Coincides with radiation sessions, for 2 months

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ClinicalTrials.gov: NCT06165653

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Phase NA

3

Headband and Meditation for Improving <span class="highlight">Anxiety</span> and Insomnia for People with Stage I-IV Breast Cancer

Pilot Study of a Wearable EEG Headband as a Meditation Device for Breast Cancer Survivors

Purpose: To study the ability of the MUSE S headband and MUSE phone app to reduce <span class="highlight">anxiety</span> and insomnia.

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who were diagnosed within the last 10 years. You must be experiencing <span class="highlight">anxiety</span> and insomnia (sleep problems). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">MUSE S headband, nightly for 2 months</li> <li class="seamTextUnorderedListItem">Meditation with MUSE phone app, for at least 5 minutes daily, for 2 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Anxiety and insomnia (sleep problems) are among the most common side effects of breast cancer.</li> <li class="seamTextUnorderedListItem">Meditation is an effective tool to decrease stress and <span class="highlight">anxiety.</li></span> <li class="seamTextUnorderedListItem">The MUSE S headband sends EEG signals to your brain to improve fatigue, quality of life, and stress.</li> <li class="seamTextUnorderedListItem">You will be asked to wear the MUSE S headband to bed every night and meditate using the MUSE phone app for at least 5 minutes every day.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06274034' target='_blank'>ClinicalTrials.gov</a> </li></ul>
3

Headband and Meditation for Improving <span class="highlight">Anxiety</span> and Insomnia for People with Stage I-IV Breast Cancer

Pilot Study of a Wearable EEG Headband as a Meditation Device for Breast Cancer Survivors
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Nearest Location from 94108:
1615 miles
Mayo Clinic in Rochester
Rochester, MN

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Visits:
Number of visits unavailable, over 2 months

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ClinicalTrials.gov: NCT06274034

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Phase I

4

Registry of Mammograms to Improve Artificial Intelligence Analysis of Scans

UCF MammoChat: An AI-Driven Platform for Personalized Breast Cancer Patient Support -Image Repository

Purpose: To develop artificial intelligence (AI) models to better read diagnostic mammograms.

Who is this for?: People who have received a mammogram. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Provide consent to donate your mammogram.</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Around half of women will receive a false positive mammogram result (a report of cancer when cancer is not actually present). This creates <span class="highlight">anxiety.</li></span> <li class="seamTextUnorderedListItem">Artificial intelligence (AI) may be able to better read mammograms to reduce false positive results. AI models need to be improved for different racial groups, age ranges, ethnicities, and different types of breast cancer.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07214883' target='_blank'>ClinicalTrials.gov</a> </li></ul>
4

Registry of Mammograms to Improve Artificial Intelligence Analysis of Scans

UCF MammoChat: An AI-Driven Platform for Personalized Breast Cancer Patient Support -Image Repository
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Nearest Location from 94108:
2447 miles
University of Central Florida
Orlando, FL

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Visits:
No visits required

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ClinicalTrials.gov: NCT07214883

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Phase NA

5

Mindfulness Program to Promote Sexual Health after Breast Cancer

Virtual Mindful After Cancer Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

Purpose: To study the effects of a mindfulness-based program and how it may help improve quality of life and sexual health in women with breast cancer.

Who is this for?: Women with stage I or stage II or stage III or stage IV (metastatic) breast cancer who were diagnosed at least 6 months ago, and have at least one concern related to sexual health or body image. View full eligibility criteria

What's involved?


What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">This study is testing a virtual program called Mindful After Cancer (MAC). The program is designed to help people with breast (and gynecologic) cancer manage concerns about sexual health and body image after treatment.</li> <li class="seamTextUnorderedListItem">Researchers with test how well the program can help in areas such as: sexual well-being and satisfaction, body image, emotional health (including <span class="highlight">anxiety</span> and mood), mindfulness, self-confidence in managing health, and overall quality of life.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT07055854' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.lbbc.org/about-breast-cancer/wellness-body-image/how-breast-cancer-impacts-your-body-image' target='_blank'>Living Beyond Breast Cancer: Body Image and Breast Cancer</a> </li></ul>
5

Mindfulness Program to Promote Sexual Health after Breast Cancer

Virtual Mindful After Cancer Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors
No Travel Required
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Visits:
No visits required

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ClinicalTrials.gov: NCT07055854

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Phase I

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