You have matched to 15 trials

Guest Profile:  No profile selected

Sort by zip code: 94108 Hide Map Icon
mail-icon

Register to sign up for Trial Alerts

Receive emails about new trials that match your profile.
1

Paclitaxel Alone or With Radium-223 Dichloride For Metastatic HER2 Negative Breast Cancer With Bone Metastases

Phase II Trial of Radium-223 Dichloride in Combination With Paclitaxel in Patients With Bone Metastatic Breast Cancer

Purpose: To study the anti-cancer activity and effects (good and bad) of giving radium-223 dichloride (a type of radiation therapy given by IV) in combination with paclitaxel (Taxol®).

Who is this for?: People with metastatic (stage IV), HER2 negative (HER2-) breast cancer that has spread to the bone and who have not received more than three lines of chemotherapy for metastatic disease. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®), by IV, weekly (3 weeks on, 1 week off), ongoing</li> <li class="seamTextUnorderedListItem">Radium 223 dichloride (Xofigo®), by IV, once a month, for 6 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Standard of care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®), by IV, weekly (3 weeks on, 1 week off), ongoing</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®) is a chemotherapy drug routinely used to treat metastatic breast cancer.</li> <li class="seamTextUnorderedListItem">Radium-223 dichloride (Xofigo®) is a radiation therapy given by IV. It works by killing cancer cells and may reduce the <span class="highlight">pain</span> caused by bone metastases. </li> <li class="seamTextUnorderedListItem">Radium-223 dichloride (Xofigo®) is approved to treat metastatic prostate cancer that has spread to the bones. Its use in breast cancer is considered experimental.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04090398' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/research-news/oral-vs-iv-paclitaxel-for-mbc' target='_blank'>Breastcancer.org: Is Oral Paclitaxel Better Than IV Paclitaxel for Metastatic Breast Cancer?</a> </li><li class='seamTextUnorderedListItem'><a href='http://chemocare.com/chemotherapy/drug-info/radium-223-dichloride.aspx' target='_blank'>Chemocare: Radium 223 Dichloride</a> </li><li class='seamTextUnorderedListItem'><a href='https://en.wikipedia.org/wiki/Radium-223' target='_blank'>Wikipedia: Radium-223</a> </li><li class='seamTextUnorderedListItem'><a href='http://mbcn.org/bone-mets/' target='_blank'>Metastatic Breast Cancer Network: Bone Mets</a> </li></ul>
1

Paclitaxel Alone or With Radium-223 Dichloride For Metastatic HER2 Negative Breast Cancer With Bone Metastases

Phase II Trial of Radium-223 Dichloride in Combination With Paclitaxel in Patients With Bone Metastatic Breast Cancer
Icon

Nearest Location:
355 miles
City of Hope Comprehensive Cancer Center
Duarte, CA

Icon

Visits:
3 visits a month, ongoing

Icon

ClinicalTrials.gov: NCT04090398

Icon

Phase II

2

Sulfasalazine to Decrease <span class="highlight">Pain</span> and Opioid Use in People with Breast Cancer

Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients

Purpose: To study if sulfasalazine, an anti-inflammatory drug, can decrease <span class="highlight">pain</span> and the use of opioid <span class="highlight">pain</span> medication.

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have experienced <span class="highlight">pain</span> for at least 1.5 months and receive opioid <span class="highlight">pain</span> medication. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Standard of Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for sulfasalazine, by mouth, daily</li> <li class="seamTextUnorderedListItem">Continue current opioid <span class="highlight">pain</span> medication</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Sulfasalazine, by mouth, daily</li> <li class="seamTextUnorderedListItem">Continue current opioid <span class="highlight">pain</span> medication</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">People with cancer-induced <span class="highlight">pain</span> are now taking increasing doses of opioids to control their <span class="highlight">pain.</li></span> <li class="seamTextUnorderedListItem">The gold standard to manage <span class="highlight">pain</span> is opioids. Opioids come with significant side effects that limit the amount of opioids that can be safely given.</li> <li class="seamTextUnorderedListItem">Sulfasalazine is an anti-inflammatory drug with an established safety profile. It has been in use for over 50 years for the treatment of inflammatory conditions such as arthritis.</li> <li class="seamTextUnorderedListItem">Sulfasalazine may also decrease the survival of cancer cells.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03847311' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a682204.html' target='_blank'>Medline Plus: Sulfasalazine</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment-side-effects/pain' target='_blank'>Breastcancer.org: Pain</a> </li></ul>
2

Sulfasalazine to Decrease <span class="highlight">Pain</span> and Opioid Use in People with Breast Cancer

Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients
Icon

Nearest Location:
753 miles
Banner University Medical Center North Campus
Tucson, AZ

Icon

Visits:
Number of visits unavailable

Icon

ClinicalTrials.gov: NCT03847311

Icon

Phase II

3

GM1 to Reduce or Prevent Nerve <span class="highlight">Pain</span> During Chemotherapy for Metastatic Breast Cancer

An Early Phase and Phase II Clinical Trial to Evaluate Ganglioside-Monosialic Acid (GM1) for Preventing Paclitaxel-Associated Neuropathy

Purpose: To study the ability of GM1 to reduce or prevent nerve <span class="highlight">pain</span> during treatment with paclitaxel (Taxol®) chemotherapy.

Who is this for?: People with metastatic (stage IV) breast cancer who are planning to receive treatment with paclitaxel (Taxol®) chemotherapy. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">GM1, by IV, weekly for 4 months</li> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®), by IV, weekly for 4 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for GM1, by IV, weekly for 4 months</li> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®), by IV, weekly for 4 months</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Neuropathy is nerve <span class="highlight">pain</span> in your hands and feet as a side effect of cancer treatment such as chemotherapy.</li> <li class="seamTextUnorderedListItem">GM1 is a part of the body's natural system that protects nerves from damage.</li> <li class="seamTextUnorderedListItem">Chemotherapy drugs, such as paclitaxel (Taxol®), work in different ways to stop the growth of cancer cells, either by killing the cells, stopping them from dividing, or stopping them from spreading.</li> <li class="seamTextUnorderedListItem">This trial is also available in Spanish.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05751668' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/drugs/taxol' target='_blank'>Breastcancer.org: Paclitaxel (Taxol®)</a> </li></ul>
3

GM1 to Reduce or Prevent Nerve <span class="highlight">Pain</span> During Chemotherapy for Metastatic Breast Cancer

An Early Phase and Phase II Clinical Trial to Evaluate Ganglioside-Monosialic Acid (GM1) for Preventing Paclitaxel-Associated Neuropathy
Icon

Nearest Location:
1387 miles
University of Oklahoma Health Sciences Center
Oklahoma City, OK

Icon

Visits:
1 visit every week for 4 months

Icon

ClinicalTrials.gov: NCT05751668

Icon

Phase II

4

Studying Speech, Movement, and Senses During Brain Surgery for Brain Metastasis

Assessment of Reorganization and Plasticity of Eloquent Function in Patients With Brain Tumors

Purpose: To study how brain tumors affect your speech, movement, and senses and to develop new methods of diagnosing brain tumors.

Who is this for?: People with metastatic (stage IV) breast cancer that has spread to the brain (brain metastasis). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cognitive testing</li> <li class="seamTextUnorderedListItem">MRI and fMRI scans</li> <li class="seamTextUnorderedListItem">DTI tractograms</li> <li class="seamTextUnorderedListItem">MEG studies</li> </ul> <p class="seamTextPara"> followed by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Awake brain mapping and surgery to remove brain tumor</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">A craniotomy is a type of brain surgery. The surgeon will remove part of your skull (cranium) to access your brain to remove the tumors.</li> <li class="seamTextUnorderedListItem">You will be awake during the craniotomy to monitor how the surgery is affecting your speech, movement, and senses. Your scalp will be anesthetized, so you will not feel the operation or any <span class="highlight">pain.</li></span> <li class="seamTextUnorderedListItem">You will receive cognitive testing, MRI and fMRI scans, DTI tractograms, and MEG studies before and after surgery.</li> <li class="seamTextUnorderedListItem">Cognitive tests study your cognition, which is your ability to think.</li> <li class="seamTextUnorderedListItem">Magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI) scans produce brain images created by magnetic energy rather than x-ray energy.</li> <li class="seamTextUnorderedListItem">A DTI tractogram is a type of MRI scan that produces brain images created by radio waves and magnetic fields.</li> <li class="seamTextUnorderedListItem">MEG studies measure the magnetic fields produced by your brain.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT01535430' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://mbcbrainmets.org/' target='_blank'>MBCBrainMets.org</a> </li><li class='seamTextUnorderedListItem'><a href='https://braintumorcenter.ucsf.edu/treatments/surgery/awake-brain-mapping-faq' target='_blank'>UCSF Brain Tumor Center: Awake Craniotomy</a> </li></ul>
4

Studying Speech, Movement, and Senses During Brain Surgery for Brain Metastasis

Assessment of Reorganization and Plasticity of Eloquent Function in Patients With Brain Tumors
Icon

Nearest Location:
1418 miles
University of Nebraska Medical Center
Omaha, NE

Icon

Visits:
May require hospitalization

Icon

ClinicalTrials.gov: NCT01535430

Icon

Phase NA

5

Studying Nerve <span class="highlight">Pain</span> from T-DM1 in People with Stage I-IV HER2 Positive Breast Cancer

A Study of the Natural History of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients

Purpose: To study how trastuzumab emtansine (T-DM1, Kadcyla®) causes nerve <span class="highlight">pain</span> in people with and without previous nerve <span class="highlight">pain.</span>

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) HER2 positive (HER2+) breast cancer who are planning to receive treatment with trastuzumab emtansine (T-DM1, Kadcyla®). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Neuropathy is nerve <span class="highlight">pain</span> in your hands and feet as a side effect of cancer treatment. Neuropathy is <span class="highlight">pain</span> from nerve damage.</li> <li class="seamTextUnorderedListItem">Trastuzumab emtansine (T-DM1, Kadcyla®) is an antibody drug conjugate (ADC).</li> <li class="seamTextUnorderedListItem">An ADC is a type of therapy that combines an antibody that targets cancer cells with a therapy that can kill cancer cells. Because the antibody only targets cancer cells, the ADC does not kill normal cells, making it less likely to cause side effects.</li> <li class="seamTextUnorderedListItem">T-DM1's antibody targets HER2, a protein that is expressed by some breast cancer cells, and it delivers an anti-cancer drug called emtansine.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05889988' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/targeted-therapy/kadcyla' target='_blank'>Breastcancer.org: Trastuzumab Emtansine (T-DM1, Kadcyla®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment-side-effects/neuropathy' target='_blank'>Breastcancer.org: Nerve Pain</a> </li></ul>
5

Studying Nerve <span class="highlight">Pain</span> from T-DM1 in People with Stage I-IV HER2 Positive Breast Cancer

A Study of the Natural History of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients
Icon

Nearest Location:
1455 miles
Sanford Health Worthington
Worthington, MN

Icon

Visits:
Number of visits unavailable

Icon

ClinicalTrials.gov: NCT05889988

Icon

Phase NA

6

Botulinum Toxin A for Nerve <span class="highlight">Pain</span> Caused by Chemotherapy in People with Breast Cancer

Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Purpose: To study the safety and ability of incobotulinumtoxinA (INA) (Xeomin®) to treat chemotherapy induced peripheral neuropathy (CIPN).

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have chemotherapy induced peripheral neuropathy (CIPN). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">IncobotulinumtoxinA (INA) (Xeomin®), by injections into hands or feet, 1 time</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Control</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Saline water, by injections into hands or feet, 1 time</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Additional Procedures</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires, 5 times within 6 months</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Chemotherapy induced peripheral neuropathy (CIPN) is nerve <span class="highlight">pain</span> in your hands and feet as a side effect of chemotherapy.</li> <li class="seamTextUnorderedListItem">Neuropathy is <span class="highlight">pain</span> from nerve damage.</li> <li class="seamTextUnorderedListItem">IncobotulinumtoxinA (INA) (Xeomin®) may help treat nerve <span class="highlight">pain</span> by inhibiting parts of the <span class="highlight">pain</span> signaling pathway.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03571334' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cancer.org/treatment/treatments-and-side-effects/physical-side-effects/peripheral-neuropathy/what-is-peripherial-neuropathy.html' target='_blank'>American Cancer Society: Chemotherapy Induced Peripheral Neuropathy (CIPN)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.webmd.com/drugs/2/drug-154593/xeomin-intramuscular/details' target='_blank'>WebMD: IncobotulinumtoxinA (INA) (Xeomin®)</a> </li></ul>
6

Botulinum Toxin A for Nerve <span class="highlight">Pain</span> Caused by Chemotherapy in People with Breast Cancer

Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy
Icon

Nearest Location:
1832 miles
Froedtert Hospital
Milwaukee, WI

Icon

Visits:
1 visit

Icon

ClinicalTrials.gov: NCT03571334

Icon

Phase II

7

Hypnosis for <span class="highlight">Pain</span> in Black Women With Advanced Breast Cancer: A Feasibility Study

Hypnosis for <span class="highlight">Pain</span> in Black Women With Advanced Breast Cancer: A Feasibility Study

Purpose: To study the ability of hypnosis to decrease <span class="highlight">pain</span> in Black women with metastatic breast cancer.

Who is this for?: Black women with metastatic (stage IV) breast cancer who are experiencing <span class="highlight">pain.</span> View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Hypnosis</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Listen to hypnosis audio, at home, daily for 1.5 months</li> <li class="seamTextUnorderedListItem">Hypnosis log</li> <li class="seamTextUnorderedListItem">Surveys</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: White Noise</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Listen to white noise audio, at home, daily for 1.5 months</li> <li class="seamTextUnorderedListItem">Hypnosis log</li> <li class="seamTextUnorderedListItem">Surveys</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Hypnosis is a technique that helps people become calm, relaxed, and conscious of making change.</li> <li class="seamTextUnorderedListItem">You may continue to use current <span class="highlight">pain</span> treatment during the trial.</li> <li class="seamTextUnorderedListItem">You will receive a MP3 player with the audio files. Each audio session is about 20 minutes.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06057636' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://scopeblog.stanford.edu/2023/04/14/how-hypnosis-can-alter-the-brains-perception-of-pain/' target='_blank'>Stanford Medicine: Hypnosis for Pain</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/resources-support/complementary-integrative-medicine/' target='_blank'>Metastatic Trial Talk: What is Complementary and Integrative Medicine?</a> </li></ul>
7

Hypnosis for <span class="highlight">Pain</span> in Black Women With Advanced Breast Cancer: A Feasibility Study

Hypnosis for <span class="highlight">Pain</span> in Black Women With Advanced Breast Cancer: A Feasibility Study
Icon

Nearest Location:
1838 miles
University of Tennessee Knoxville
Knoxville, TN

Icon

Visits:
No visits required

Icon

ClinicalTrials.gov: NCT06057636

Icon

Phase NA

8

Physical Therapy and Education Before Treatment for Women with Stage 0-IV Breast Cancer

A Randomized Pilot Test of the Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Functional Recovery (MOve-ABC) (B-PREPed)

Purpose: To study the ability of the Moving On After Breast Cancer (MOve-ABC) program to provide physical therapy and education before breast cancer treatment.

Who is this for?: Women with newly diagnosed stage 0 (DCIS), stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have not yet received treatment. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Moving On After Breast Cancer (MOve-ABC) Program</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education about breast cancer side effects</li> <li class="seamTextUnorderedListItem">Physical therapy evaluation</li> <li class="seamTextUnorderedListItem">Home exercise program</li> <li class="seamTextUnorderedListItem">Phone calls and text messages</li> <li class="seamTextUnorderedListItem">Additional referrals (if needed)</li> <li class="seamTextUnorderedListItem">Questionnaires</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Education on surgery recovery and <span class="highlight">pain</span> management</li> <li class="seamTextUnorderedListItem">Additional referrals (if needed)</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Physical therapy before cancer treatment aims to help with early identification and self-management of treatment side effects.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06081127' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/managing-life/exercise' target='_blank'>Breastcancer.org: Exercise and Breast Cancer</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cedars-sinai.org/health-library/diseases-and-conditions/p/physical-therapy---breast-cancer.html' target='_blank'>Cedars Sinai: Physical Therapy for Breast Cancer</a> </li></ul>
8

Physical Therapy and Education Before Treatment for Women with Stage 0-IV Breast Cancer

A Randomized Pilot Test of the Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Functional Recovery (MOve-ABC) (B-PREPed)
Icon

Nearest Location:
1856 miles
Northwestern University
Chicago, IL

Icon

Visits:
3 visits within 1 year

Icon

ClinicalTrials.gov: NCT06081127

Icon

Phase I

9

Apollo Wearable Device to Reduce Fatigue and <span class="highlight">Pain</span> for People with Metastatic Breast Cancer

Apollo Device for Fatigue in Metastatic Breast Cancer

Purpose: To study if the Apollo wearable device can reduce fatigue and <span class="highlight">pain.</span>

Who is this for?: Women with metastatic (stage IV) breast cancer who experience fatigue. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Apollo wearable device</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Additional Procedures</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Apollo is a wearable device, similar to a FitBit, that emits vibrations.</li> <li class="seamTextUnorderedListItem">Apollo vibrations activate touch receptors in your skin that are perceived as safety signals by your brain to decrease stress and improve recovery, focus, and energy.</li> <li class="seamTextUnorderedListItem">Apollo is about the size of an Apple watch and can be worn on your ankle, wrist, or arm with two adjustable fabric straps.</li> <li class="seamTextUnorderedListItem">Fatigue is feeling tired.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT04983342' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://apolloneuro.com/' target='_blank'>Apollo Neuroscience: Apollo Device</a> </li></ul>
9

Apollo Wearable Device to Reduce Fatigue and <span class="highlight">Pain</span> for People with Metastatic Breast Cancer

Apollo Device for Fatigue in Metastatic Breast Cancer
Icon

Nearest Location:
2264 miles
Magee Womens Hospital
Pittsburgh, PA

Icon

Visits:
Number of visits unavailable

Icon

ClinicalTrials.gov: NCT04983342

Icon

Phase NA

10

Studying the Amount of Chemotherapy in the Blood in People with Breast Cancer

Pilot Feasibility Study of Paclitaxel Therapeutic Drug Monitoring in Cancer Patients

Purpose: To study the ability of researchers to measure the amount of paclitaxel (Taxol®) in blood and study the effect of paclitaxel (Taxol®) on neuropathy.

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are planning to receive treatment with paclitaxel (Taxol®) at Wake Forest Comprehensive Cancer Center. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood draws</li> <li class="seamTextUnorderedListItem">Surveys about neuropathy</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for trial schedule</i></p>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Paclitaxel (Taxol®) is a chemotherapy drug.</li> <li class="seamTextUnorderedListItem">Neuropathy is <span class="highlight">pain</span> from nerve damage.</li> <li class="seamTextUnorderedListItem">Nerve damage is one of the most common and severe side effects of paclitaxel (Taxol®).</li> <li class="seamTextUnorderedListItem">The ability to consistently measure paclitaxel (Taxol®) in the blood may allow doctors to control the dose of paclitaxel, so that enough chemotherapy is given to kill the cancer, but the side effect of nerve damage is reduced.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03987555' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://breastcancernow.org/information-support/facing-breast-cancer/going-through-treatment-breast-cancer/chemotherapy/paclitaxel-taxol' target='_blank'>Breast Cancer Now: Paclitaxel (Taxol®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/side_effects/neuropathy' target='_blank'>Breastcancer.org: Neuropathy</a> </li></ul>
10

Studying the Amount of Chemotherapy in the Blood in People with Breast Cancer

Pilot Feasibility Study of Paclitaxel Therapeutic Drug Monitoring in Cancer Patients
Icon

Nearest Location:
2314 miles
Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, NC

Icon

Visits:
Number of visits unavailable

Icon

ClinicalTrials.gov: NCT03987555

Icon

Phase NA

11

A Blood Test to Study Bone <span class="highlight">Pain</span> Related to Breast Cancer that has Spread to the Bones (Bone Metastases)

The Role of Histamine in Breast Cancer Bone <span class="highlight">Pain</span>

Purpose: To study how certain blood markers relate to bone <span class="highlight">pain</span> in breast cancer that has spread to the bone.

Who is this for?: People with metastatic (stage IV) breast cancer that has spread to the bone (bone metastases). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Blood draw, at least one time</li> <li class="seamTextUnorderedListItem">Questionnaires </li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Please contact research site for trial schedule</i></p>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Cancer that has spread to the bone is called bone metastases. </li> <li class="seamTextUnorderedListItem">This trial is studying certain blood markers to see how they relate to bone <span class="highlight">pain.</li></span> <li class="seamTextUnorderedListItem">The markers being studied include histamines. </li> <li class="seamTextUnorderedListItem">Histamines are a biological signal that trigger your immune system.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT03529565' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/from-the-experts/diagnosing-treating-bone-metastases/' target='_blank'>Metastatic Trial Talk: Diagnosing & Treatment of Bone Metastases</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992892/#:~:text=Further%20studies%20support%20the%20role,the%20onset%20of%20malignant%20transformation.' target='_blank'>Journal Article: Histamine Receptors and Cancer</a> </li></ul>
11

A Blood Test to Study Bone <span class="highlight">Pain</span> Related to Breast Cancer that has Spread to the Bones (Bone Metastases)

The Role of Histamine in Breast Cancer Bone <span class="highlight">Pain</span>
Icon

Nearest Location:
2314 miles
Wake Forest University Health Sciences
Winston-Salem, NC

Icon

Visits:
1 visit

Icon

ClinicalTrials.gov: NCT03529565

Icon

Phase NA

12

Acupuncture for Nerve <span class="highlight">Pain</span> During Chemotherapy for People with Breast Cancer

Acupuncture for Taxane-Induced Peripheral Neuropathy Prevention (ATP): A Phase II Randomized, Placebo Controlled Trial

Purpose: To study if acupuncture can prevent nerve <span class="highlight">pain</span> from getting worse while receiving chemotherapy.

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are planning to receive treatment with paclitaxel (Taxol®) or nab-paclitaxel (Abraxane®) chemotherapy. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Acupuncture, weekly for 1-3 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Placebo for acupuncture, weekly for 1-3 months</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Some people experience a side effect while they are receiving taxane chemotherapy called taxane-induced peripheral neuropathy (TIPN).</li> <li class="seamTextUnorderedListItem">TIPN is <span class="highlight">pain</span> in the arms and legs due to nerve damage caused by cancer treatment and may interfere with quality of life.</li> <li class="seamTextUnorderedListItem">Acupuncture is a medical technique that involves insertion of very thin needles into specific areas on the body.</li> <li class="seamTextUnorderedListItem">We will compare real acupuncture (RA) to placebo (sham) acupuncture (SA). SA is done like RA, but will use different needles and target different sites or places on the body than RA.</li> <li class="seamTextUnorderedListItem">This trial is available in English or Spanish.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05458284' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/complementary-therapy/types/acupuncture' target='_blank'>Breastcancer.org: Acupuncture</a> </li></ul>
12

Acupuncture for Nerve <span class="highlight">Pain</span> During Chemotherapy for People with Breast Cancer

Acupuncture for Taxane-Induced Peripheral Neuropathy Prevention (ATP): A Phase II Randomized, Placebo Controlled Trial
Icon

Nearest Location:
2539 miles
Memorial Sloan Kettering Basking Ridge
Basking Ridge, NJ

Icon

Visits:
1 visit per week for 1-3 months

Icon

ClinicalTrials.gov: NCT05458284

Icon

Phase II

13

Studying Bone Changes in Post-Menopausal Women with Stage I-IV Breast Cancer After Treatment with Aromatase Inhibitor and Denosumab

Post-menopausal Breast Cancer Patients Treated With Aromatase Inhibitors and Denosumab: An Observational Study to Assess Rebound Bone Loss and Insufficiency Fractures After Denosumab Discontinuation

Purpose: To gather information about changes in the bones after stopping treatment with an aromatase inhibitor and denosumab (Xgeva®).

Who is this for?: Postmenopausal women with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who have completed treatment with an aromatase Inhibitor before or within 6 months of completing at least 2 doses of denosumab (Xgeva®). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Physical exam, 5 visits within 2 years</li> <li class="seamTextUnorderedListItem">DEXA scan, 2 times within 2 years</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The physical exam will include history and <span class="highlight">pain</span> assessment for development of new fractures, weight and height measurement with BMI (body mass index) calculation, and blood work.</li> <li class="seamTextUnorderedListItem">Dual-energy X-ray absorptiometry (DEXA) scans use x-ray energy to measure bone density (thickness and strength of bones).</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05590949' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.cdc.gov/nceh/radiation/dexa-scan.html#:~:text=DEXA%20(dual%20x%2Dray%20absorptiometry,the%20hip%20and%20the%20spine.' target='_blank'>CDC: DEXA Scan</a> </li><li class='seamTextUnorderedListItem'><a href='https://medlineplus.gov/druginfo/meds/a610023.html' target='_blank'>MedlinePlus: Denosumab (Xgeva®)</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/hormonal-therapy' target='_blank'>Breastcancer.org: Aromatase Inhibitors</a> </li></ul>
13

Studying Bone Changes in Post-Menopausal Women with Stage I-IV Breast Cancer After Treatment with Aromatase Inhibitor and Denosumab

Post-menopausal Breast Cancer Patients Treated With Aromatase Inhibitors and Denosumab: An Observational Study to Assess Rebound Bone Loss and Insufficiency Fractures After Denosumab Discontinuation
Icon

Nearest Location:
2539 miles
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, NJ

Icon

Visits:
5 visits

Icon

ClinicalTrials.gov: NCT05590949

Icon

Phase NA

14

Integrative Medicine at Home Program for People With Stage I-IV Breast Cancer

Integrative Medicine for Patient-reported Outcomes, Values, and Experience (IMPROVE)

Purpose: To find out whether the Integrative Medicine at Home program can help reduce symptoms and improve treatment satisfaction.

Who is this for?: People with stage I, stage II, stage III, or stage IV (metastatic) breast cancer who are currently receiving treatment. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will be randomly assigned to 1 of 2 groups: </p> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 1: Experimental</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Integrative Medicine at Home program, 3 months</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Group 2: Enhanced Usual Care</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Integrative medicine handout</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">The Integrative Medicine at Home program offers virtual (online rather than in-person) group classes focusing on mind-body practice.</li> <li class="seamTextUnorderedListItem">Mind-body practice is a health practice that combines mental focus, controlled breathing, and body movements to help relax the body and mind and reduce symptoms such as tiredness, <span class="highlight">pain,</span> or insomnia.</li> <li class="seamTextUnorderedListItem">The classes will be led by an Integrative Medicine Service (IMS) clinical therapist using Zoom video conferencing platform.</li> <li class="seamTextUnorderedListItem">If you are in Group 2, you will be given a handout to encourage you to visit Memorial Sloan Kettering's Integrative Medicine website to access pre-recorded, on-demand meditation videos and audios.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling people with other types of cancer.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05053230' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.mskcc.org/cancer-care/diagnosis-treatment/symptom-management/integrative-medicine' target='_blank'>Memorial Sloan Kettering Cancer Center: Integrative Medicine</a> </li></ul>
14

Integrative Medicine at Home Program for People With Stage I-IV Breast Cancer

Integrative Medicine for Patient-reported Outcomes, Values, and Experience (IMPROVE)
No Travel Required
Icon

Visits:
No visits required

Icon

ClinicalTrials.gov: NCT05053230

Icon

Phase NA

15

App to Improve Attention and Reduce <span class="highlight">Pain</span> for People with Stage I-IV Breast Cancer

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Purpose: To study the ability of the CT-100 app to improve attention and cognition and reduce <span class="highlight">pain.</span>

Who is this for?: People 22-65 years old with stage I, stage II, stage III, or stage IV (metastatic) breast cancer. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">CT-100 app</li> <li class="seamTextUnorderedListItem">Questionnaires</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">CT-100 is an experimental app that may improve attention and cognition (ability to think) and reduce <span class="highlight">pain.</li></span> <li class="seamTextUnorderedListItem">You will receive compensation for participating in this trial.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06136923' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.clicktherapeutics.com/products/' target='_blank'>Click Therapeutics: CT-100 App Information Page</a> </li></ul>
15

App to Improve Attention and Reduce <span class="highlight">Pain</span> for People with Stage I-IV Breast Cancer

An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer
No Travel Required
Icon

Visits:
No visits required

Icon

ClinicalTrials.gov: NCT06136923

Icon

Phase NA

HELP GUIDE
HELP GUIDE