You have matched to 1 trial

Guest Profile:  No profile selected

Sort by zip code: 94107 Hide Map Icon
mail-icon

Register to sign up for Trial Alerts

Receive emails about new trials that match your profile.
1

186RNL Radioactive Drug for People with Leptomeningeal Metastases

A Multicenter Phase 1 Clinical Study to Determine the Maximum Tolerated Dose/Maximum Feasible Dose, Safety,& Efficacy of Single Dose Rhenium-186 NanoLiposome (186RNL) (ReSPECT-LM) Administered Via Intraventricular Catheter for Leptomeningeal Metastases

Purpose: To study the safety, effects (good and bad), and anti-cancer activity of rhenium-186 nanoliposome (186RNL), an experimental radionuclide.

Who is this for?: People with metastatic (stage IV) breast cancer that has spread to the leptomeninges (leptomeningeal metastasis or leptomeningeal disease). View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Procedure to place Ommaya reservoir under the scalp</li> <li class="seamTextUnorderedListItem">MRI scan</li> </ul> <p class="seamTextPara"> followed up to 1 week later by: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Rhenium-186 nanoliposome (186RNL), via Ommaya reservoir, 1 time</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">Rhenium-186 nanoliposome (186RNL) is an experimental radionuclide (also called radiopharmaceutical or radioactive drug).</li> <li class="seamTextUnorderedListItem">186RNL may slow or stop cancer cells from growing.</li> <li class="seamTextUnorderedListItem">Ommaya reservoirs are very small plastic devices put under the scalp to give access to cerebrospinal fluid (CSF), the fluid or liquid surrounding your brain and spinal cord.</li> <li class="seamTextUnorderedListItem">A magnetic resonance imaging (MRI) scan produces body pictures created by using magnetic energy.</li> <li class="seamTextUnorderedListItem">In this trial, the MRI scans will study the flow of CSF in your body.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05034497' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.respect-trials.com/lm/' target='_blank'>Plus Therapeutics: Trial Information Page</a> </li><li class='seamTextUnorderedListItem'><a href='https://plustherapeutics.com/186rnl/' target='_blank'>Plus Therapeutics: 186RNL Drug Information Page</a> </li></ul>
1

186RNL Radioactive Drug for People with Leptomeningeal Metastases

A Multicenter Phase 1 Clinical Study to Determine the Maximum Tolerated Dose/Maximum Feasible Dose, Safety,& Efficacy of Single Dose Rhenium-186 NanoLiposome (186RNL) (ReSPECT-LM) Administered Via Intraventricular Catheter for Leptomeningeal Metastases
Icon

Nearest Location:
1481 miles
UT Health Science Center San Antonio / Mays Cancer Center
San Antonio, TX

Icon

Visits:
May require surgery

Icon

ClinicalTrials.gov: NCT05034497

Icon

Phase I

HELP GUIDE
HELP GUIDE