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1

ADRX-0706 Antibody Drug Conjugate for Advanced Triple Negative Breast Cancer

A Phase 1a/b Study of ADRX-0706 in Subjects with Select Advanced Solid Tumors

Purpose: To study the safety, best dose, and effects (good and bad) of ADRX-0706, an experimental antibody drug conjugate.

Who is this for?: People with advanced (some stage III) or metastatic (stage IV) triple negative (ER-, PR-, HER2-) breast cancer who have no standard treatment options available. You must have received at least 1 line of therapy for advanced disease. View full eligibility criteria

What's involved?

<p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">ADRX-0706</li></ul>

What's being studied?

<ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">ADRX-0706 is an experimental targeted therapy called an antibody drug conjugate (ADC).</li> <li class="seamTextUnorderedListItem">An antibody drug conjugate (ADC) is a type of therapy that combines an antibody that targets cancer cells with a therapy that can kill cancer cells.</li> <li class="seamTextUnorderedListItem">Because the antibody only targets cancer cells, the ADC does not kill normal cells, making it less likely to cause side effects.</li> <li class="seamTextUnorderedListItem">ADRX-0706's antibody targets nectin-4, a protein that is expressed by some breast cancer cells, and it delivers an anti-cancer drug.</li></ul>

How can I learn more?

<ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT06036121' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://metastatictrialtalk.org/research-news/antibody-drug-conjugates' target='_blank'>Metastatic Trial Talk: Update On Antibody-Drug Conjugates (ADCs) For MBC</a> </li></ul>
1

ADRX-0706 Antibody Drug Conjugate for Advanced Triple Negative Breast Cancer

A Phase 1a/b Study of ADRX-0706 in Subjects with Select Advanced Solid Tumors
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Nearest Location:
339 miles
UCLA
Los Angeles, CA

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Visits:
Number of visits unavailable

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ClinicalTrials.gov: NCT06036121

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Phase I

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