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NEAREST SITE: 0 miles
NEXT Oncology
San Antonio, TX

VISITS: 1 visit every 3 weeks

PHASE: I-II

NCT ID: NCT05094804

OR2805 Immunotherapy for Advanced Breast Cancer

A Phase 1-2 Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With a PD-1 Inhibitor in Subjects With Advanced Malignancies (NCT05094804) Scientific Title

Purpose
To study the safety, best dose, effects (good and bad), and anti-cancer activity of OR2805, an experimental immunotherapy.
Who is this for?
People with advanced (some stage III) or metastatic (stage IV) breast cancer that has progressed on standard treatment.    Full eligibility criteria
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  • <p class="seamTextPara"> You will receive the following: </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">OR2805, by IV, every 3 weeks</li> </ul> <p class="seamTextPara"> <i class="seamTextEmphasis">Additional Procedures</i> </p> <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">May require 1 biopsy</li></ul>
  • <ul class="seamTextUnorderedList"> <li class="seamTextUnorderedListItem">OR2805 is an experimental immunotherapy that targets CD163 and activates immune cells called T cells to detect and fight cancer cells.</li> <li class="seamTextUnorderedListItem">This trial is also enrolling patients with other types of cancers.</li></ul>
  • <ul class='seamTextUnorderedList'><li class='seamTextUnorderedListItem'>View eligibility criteria and additional trial information: <a href='https://clinicaltrials.gov/ct2/show/NCT05094804' target='_blank'>ClinicalTrials.gov</a> </li><li class='seamTextUnorderedListItem'><a href='https://oncoresponse.com/pipeline/pipeline.php' target='_blank'>OncoResponse Drug Information Page: OR2805</a> </li><li class='seamTextUnorderedListItem'><a href='https://www.breastcancer.org/treatment/immunotherapy' target='_blank'>Breastcancer.org: Immunotherapy</a> </li></ul>
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