International Brain Mets Trials - Currently Recruiting
Brain mets trials that are currently recruiting in the U.S. are included on Metastatic Trial Search. See below for other international brain mets trials that are currently recruiting.
Asia
A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline (NCT02504788)
Neurocognitive Impact and Dose-Effect Relationship of Hippocampal Avoidance During Whole Brain Radiotherapy Plus Simultaneous Integrated Boost - A Prospective Follow-up Study (NCT03223675)
Effects of Intraoperative GDFT on the Postoperative Brain Edema (NCT03323580)
HFSRT With Concurrent TMZ for Large BMs (NCT03778541)
Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC (NCT04147728)
Camrelizumab Combined With Local Treatment in NSCLC Patients With BM (NCT04291092)
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT (NCT04452084)
Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials (NCT04725032)
A Single Arm Study of Brain Metastasis in Patients With HER2-positive Breast Cancer (NCT04767828)
MEP and Neuromuscular Blocker (NCT04768400)
A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY) (NCT04778800)
Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases (NCT04801342)
A Neurocognitive Study in Patients With Brain Oligometastases Receiving Hypofractionated SRT (NCT04805255)
CURATE.AI COR-Tx Trial for Post Brain Radiotherapy Patients (NCT04848935)
Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors (NCT04901806)
The Application of Glucose CEST MR Imaging in Brain Tumor (NCT04945499)
Phase 1 Trial for Tumor Treating Field for Drug/Radiation Resistant Brain Metastases (NCT04967027)
Toripalimab Combined With Anlotinib and SBRT in Patients With Untreated Brain Metastases of Driven Gene-negative NSCLC (NCT05021328)
Osimertinib Combined With Bevacizumab in Patients With Brain Metastasis Epidermal Growth Factor Receptor (EGFR) Mutation Positive Metastatic Non-Small Cell Lung Cancer (NCT05104281)
Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor (NCT05141877)
Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation (NCT05146219)
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy (NCT05202899)
Brain Diseases on 7.0T Magnetic Resonance Imaging (NCT05287750)
Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis (NCT05305885)
Lazertinib in Patients With NSCLC With Asymptomatic or Mild Symptomatic Brain Metastases After Failure of EGFR TKI. (NCT05326425)
Efficacy and Safety of Furmonertinib in Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases: A Single-center, Open-label, Phase II Trial（iFORCE） (NCT05465343)
Evaluation of Clinical Decision Support System for Brain Metastasis Using Brain MR Images (NCT05573815)
Australia
Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors (NCT04901806)
HyperArc Registry Study (NCT05270707)
Europe
Analysis of CMV Infections in Patients With Brain Tumors or Brain Metastases During and After Radio(Chemo)Therapy (NCT02600065)
Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn) (NCT02824731)
Cognitive Outcome After SRS or WBRT in Patients With Multiple Brain Metastases (CAR-Study B) (NCT02953717)
Intraoperative Radiotherapy After the Resection of Brain Metastases (NCT03226483)
Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases (NCT03297788)
A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases (NCT03368625)
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer (NCT03423628)
Short Course Radiation Therapy in Palliative Treatment of Brain Metastases (NCT03525301)
Hypofractionated Brain Radiationcavity (NCT03561896)
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients (NCT03694938)
Stereotactic Radiotherapy for Cerebral Metastases With Recent Hemorrhagic Signal (NCT03696680)
Radiotherapy of Multiple Brain Metastases Using AGuIX® (NCT03818386)
Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study (NCT03951142)
Evaluation of Cabozantinib in Metastatic Renal Cell Carcinoma (mRCC) With Brain Metastases (NCT03967522)
Glucocorticoids, Immunotherapy and Radiosurgery for Brain Metastases (NCT04042220)
A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours (NCT04109131)
Brain Areas of Time-To-Contact Perception: an Awake Surgery Study (NCT04128306)
Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery) (NCT04223999)
Metabolic Characterization of Space Occupying Lesions of the Brain (NCT04233788)
HA-WBRT vs SRS in Patients With Multiple Brain Metastases (NCT04277403)
Confocal Laser Endomicroscopy for Brain Tumors (NCT04280952)
Evaluation of the Best Treatment in Terms of Quality of Life for Patients Having a Brain Metastasis (NCT04358666)
Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases (NCT04397978)
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!") (NCT04474678)
Preoperative Stereotactic Radiosurgery for Brain Metastases (NCT04503772)
Evaluation of Lactate in Patients Undergoing Glial and Non Glial Mass Surgery With Craniotomy (NCT04584827)
Revision of the EORTC QLQ-BN20 Questionnaire (NCT04689321)
Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases (NCT04700748)
Use of Non-invasive Optical Analysis in Neurosurgery (NCT04712214)
Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery (NCT04785521)
Stereotactic Radiotherapy in Association With Immunotherapy for the Treatment of NSCLC Brain Metastases (NCT04787185)
Intraoperative Radiotherapy in Patients With Brain Metastases (NCT04847284)
Dose-staged Gamma Knife Radiosurgery Versus Microsurgical Resection (NCT04857905)
Detection and Metabolic Characterization in DOPA PET/CT of Brain Metastases (NCT04890028)
Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models (NCT04970615)
Brain Tumor Intraoperative Ultrasound Database (NCT05062772)
IORT After Surgical Resection of Brain Metastases (NCT05084092)
Trial of Preoperative Radiosurgery Versus Postoperative Stereotactic Radiotherapy for Resectable Brain Metastases (NCT05124236)
Re-TREAT: Re-irradiation for Relapsed Brain Metastases (NCT05126875)
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies (NCT05145049)
Hypofractionated Versus Single Fraction Stereotactic Adjuvant Radiotherapy to the Resection Cavity of Brain Metastases (NCT05160818)
BRIANSTORM - Early Identification of Patients With Brain Metastases (NCT05185557)
The Cognitive-Behavioral Dysfunctions and the Potential of Neuroplasticity in Brain Tumors Patients During Radiotherapy (NCT05192447)
The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) (NCT05267158)
Vascular Signature Mapping of Brain Tumor Genotypes (NCT05274919)
Why Still in Neurosurgical Ward After Tumor Craniotomy? (NCT05288088)
Improving Therapeutic Ratio With Hypo Fractionated Stereotactic Radiotherapy for Brain Metastases (NCT05346367)
The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? (NCT05378633)
Simulation Training in Emergency Department Imaging 2 (NCT05427838)
Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations (NCT05484219)
Sonography-guided Resection of Brain Mass Lesions (NCT05484245)
OPTIMIZATION of ADVANCED MR SEQUENCES (NCT05618990)
Middle East
Potentiation of Chemotherapy in Brain Tumors by Zinc (NCT04488783)
A Study to Assess the Efficacy of Cerebellar IMRT Combined With Cerebral SRS in Patients With Brain Metastases (NCT05477316)
North America
Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy (NCT01503086)
Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (NCT02392078)
Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS) (NCT03324360)
A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases (NCT03368625)
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases (NCT03550391)
CBF and NCF Changes With Brain Radiation (NCT03606421)
Radiosurgery With or Without Whole Brain Radiation for Multiple Metastases (NCT03775330)
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease (NCT04114981)
SWOG S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer (NCT04155034)
Brain Imaging Biomarkers in Patients With Brain Metastasis (NCT04197297)
FLT-PET / MRI Brain Mets (NCT04244019)
Accelerated Checkpoint Therapy for Any Steroid Dependent Patient With Brain Metastases (NCT04461418)
Pre- Versus Post-operative SRS for Resectable Brain Metastases (NCT04474925)
18F-DOPA II - PET Imaging Optimization (NCT04706910)
A Tailored Exercise Oncology Program for Neuro-Oncology Patients (NCT04831190)
BRAINFUL (BRAIN Tumor Focused Ultrasound-enabled Liquid Biopsy) Trial (NCT04940507)
RAPid SimPLE Targeted Radiation Treatment for Brain Metastases (NCT05050929)
Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis (NCT05095766)
Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets (NCT05317858)
Dual Perfusion Imaging for Characterizing Vascular Architecture of Brain Lesions (NCT05358340)
Biofeedback for Hemianopia Vision Rehabilitation (NCT05397873)
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